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Volumn 50, Issue 37, 2011, Pages 8584-8587

A combination of in vivo selection and cell sorting for the identification of enantioselective biocatalysts

Author keywords

biocatalysis; directed evolution; enantioselectivity; flow cytometry; in vivo selection

Indexed keywords

BIOCATALYSIS; CELL SORTING; DIRECTED EVOLUTION; ENANTIOSELECTIVE; HIGH-THROUGHPUT; IN VIVO SELECTION; IN-LINE; IN-VIVO; MUTANT LIBRARIES;

EID: 80052487039     PISSN: 14337851     EISSN: 15213773     Source Type: Journal    
DOI: 10.1002/anie.201102360     Document Type: Article
Times cited : (40)

References (38)
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    • 2,3-Dibromopropanol turned out to be the best compound after extensive investigation of various halo alcohols (data not shown) with respect to criteria, such as high toxicity of the halo alcohol vs. low toxicity of its ester on growth of E. coli, stability, and solubility in an aqueous system
    • 2,3-Dibromopropanol turned out to be the best compound after extensive investigation of various halo alcohols (data not shown) with respect to criteria, such as high toxicity of the halo alcohol vs. low toxicity of its ester on growth of E. coli, stability, and solubility in an aqueous system.
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    • true valuesand because with substrates 1 and 2 we selected substrates structurally close to the ethyl ester 3, but significantly different from the pNP esters confirming the "you get what you screen for" rule
    • true values (, L. E. Janes, R. J. Kazlauskas, J. Org. Chem. 1997, 62, 4560-4561) and because with substrates 1 and 2 we selected substrates structurally close to the ethyl ester 3, but significantly different from the pNP esters confirming the "you get what you screen for" rule.
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    • Janes, L.E.1    Kazlauskas, R.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.