Top-down quantitative proteomics identified phosphorylation of cardiac troponin i as a candidate biomarker for chronic heart failure

Journal of Proteome Research

Volumn 10, Issue 9, 2011, Pages 4054-4065

  Zhang, Jiang ^a,d,e   Guy, Moltu J ^a   Norman, Holly S ^b   Chen, Yi Chen ^a   Xu, Qingge ^a,b   Dong, Xintong ^a   Guner, Huseyin ^a   Wang, Sijian ^b   Kohmoto, Takushi ^b   Young, Ken H ^c,f   Moss, Richard L ^a,b   Ge, Ying ^a,b  

^a Human Proteomics Program   (United States)

^b Department of Physiology ^*  (United States)

^c Laboratory Medicine   (United States)

^d UNIVERSITY OF WISCONSIN MADISON   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f UNIVERSITY OF TEXAS   (United States)

Author keywords

cardiac troponin I; heart failure; phosphorylation; post translational modification; quantitative proteomics; top down mass spectrometry

Indexed keywords

BIOLOGICAL MARKER; TROPONIN I;

ARTICLE; DEPHOSPHORYLATION; DISEASE COURSE; HEART FAILURE; HEART FUNCTION; HEART HYPERTROPHY; HUMAN; HUMAN CELL; HUMAN TISSUE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; PROTEOMICS;

AMINO ACID SEQUENCE; BIOLOGICAL MARKERS; CHRONIC DISEASE; HEART FAILURE; HUMANS; LINEAR MODELS; MASS SPECTROMETRY; MOLECULAR SEQUENCE DATA; MYOCARDIUM; PHENOTYPE; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEOMICS; TROPONIN I;

EID: 80052438941     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/pr200258m     Document Type: Article

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