Single cell responses to spatially controlled photosensitized production of extracellular singlet oxygen

Photochemistry and Photobiology

Volumn 87, Issue 5, 2011, Pages 1077-1091

  Pedersen, Brian W ^a   Sinks, Louise E ^b   Breitenbach, Thomas ^a   Schack, Nickolass B ^a   Vinogradov, Sergei A ^b   Ogilby, Peter R ^a  

^a AARHUS UNIVERSITY   (Denmark)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MESOPORPHYRIN; METALLOPORPHYRIN; PALLADIUM MESO TETRA(4 CARBOXYPHENYL)PORPHINE; PALLADIUM-MESO-TETRA(4-CARBOXYPHENYL)PORPHINE; PHOTOSENSITIZING AGENT; SINGLET OXYGEN;

ARTICLE; CELL DEATH; CELL MEMBRANE; DRUG EFFECT; EXTRACELLULAR SPACE; FEMALE; HELA CELL; HUMAN; INSTRUMENTATION; LASER; METABOLISM; METHODOLOGY; MICROSCOPY; PHOTOCHEMOTHERAPY; RADIATION EXPOSURE; SINGLE CELL ANALYSIS; ULTRAVIOLET RADIATION;

CELL DEATH; CELL MEMBRANE; EXTRACELLULAR SPACE; FEMALE; HELA CELLS; HUMANS; LASERS; MESOPORPHYRINS; METALLOPORPHYRINS; MICROSCOPY; PHOTOCHEMOTHERAPY; PHOTOSENSITIZING AGENTS; SINGLE-CELL ANALYSIS; SINGLET OXYGEN; ULTRAVIOLET RAYS;

EID: 80052425984     PISSN: 00318655     EISSN: 17511097     Source Type: Journal    
DOI: 10.1111/j.1751-1097.2011.00951.x     Document Type: Article

References (65)

1. Bonnett, R., (2000) Chemical Aspects of Photodynamic Therapy. Gordon and Breach Science Publishers, Amsterdam.
2. Phillips, D., (2010) Light relief: Photochemistry and medicine. Photochem. Photobiol. Sci. 9, 1589-1596.
3. Ogilby, P. R., (2010) Singlet oxygen: There is indeed something new under the sun. Chem. Soc. Rev. 39, 3181-3209.
4. Foote, C. S., and, E. L. Clennan, (1995) Properties and reactions of singlet dioxygen. In Active Oxygen in Chemistry (Edited by, C. S. Foote, J. S. Valentine, A. Greenberg, and, J. F. Liebman,), pp. 105-140. Chapman and Hall, London.
5. Clennan, E. L., and, A. Pace, (2005) Advances in singlet oxygen chemistry. Tetrahedron 61, 6665-6691.
6. Davies, M. J., (2003) Singlet oxygen-mediated damage to proteins and its consequences. Biochem. Biophys. Res. Comm. 305, 761-770.
7. Cadet, J., J.-L. Ravanat, G. R. Martinez, M. H. G. Medeiros, and, P. Di Mascio, (2006) Singlet oxygen oxidation of isolated and cellular DNA: Product formation and mechanistic insights. Photochem. Photobiol. 82, 1219-1225.
8. Valenzeno, D. P., (1987) Photomodification of biological-membranes with emphasis on singlet oxygen mechanisms. Photochem. Photobiol. 46, 147-160.
9. Klotz, L.-O., (2002) Oxidant-induced signaling: Effects of peroxynitrite and singlet oxygen. Biol. Chem. 383, 443-456.
10. Klotz, L.-O., K.-D. Kröncke, and, H. Sies, (2003) Singlet oxygen-induced signaling effects in mammalian cells. Photochem. Photobiol. Sci. 2, 88-94.
11. Oleinick, N. L., R. L. Morris, and, I. Belichenko, (2002) The role of apoptosis in response to photodynamic therapy: What, where, why, and how. Photochem. Photobiol. Sci. 1, 1-21.
12. Redmond, R. W., and, I. E. Kochevar, (2006) Spatially-resolved cellular responses to singlet oxygen. Photochem. Photobiol. 82, 1178-1186.
13. Plaetzer, K., T. Kiesslich, T. Verwanger, and, B. Krammer, (2003) The modes of cell death induced by PDT: An overview. Med. Laser Appl. 18, 7-19.
14. Kessel, D., (2004) Correlation between subcellular localization and photodynamic therapy. J. Porphyrins Phthalocyanines 8, 1009-1014.
15. MacDonald, I. J., J. Morgan, D. A. Bellnier, G. M. Paszkiewicz, J. E. Whitaker, D. J. Litchfield, and, T. J. Dougherty, (1999) Subcellular localization patterns and their relationship to photodynamic activity of pyropheophorbide-a derivatives. Photochem. Photobiol. 70, 789-797.
16. Usuda, J., S.-M. Chiu, E. S. Murphy, M. Lam, A.-L. Nieminen, and, N. L. Oleinick, (2003) Domain-dependent photodamage to Bcl-2. J. Biol. Chem. 278, 2021-2029.
17. Rubio, N., S. P. Fleury, and, R. W. Redmond, (2009) Spatial and temporal dynamics of in vitro photodynamic cell killing: Extracellular hydrogen peroxide mediates neighboring cell death. Photochem. Photobiol. Sci. 8, 457-464.
18. Hatz, S., L. Poulsen, and, P. R. Ogilby, (2008) Time-resolved singlet oxygen phosphorescence measurements from photosensitized experiments in single cells: Effects of oxygen diffusion and oxygen concentration. Photochem. Photobiol. 84, 1284-1290.
19. Dahl, T. A., W. R. Midden, and, P. E. Hartman, (1987) Pure singlet oxygen cytotoxicity for bacteria. Photochem. Photobiol. 46, 345-352.
20. Dahl, T. A., W. R. Midden, and, P. E. Hartman, (1988) Pure exogenous singlet oxygen: Nonmutagenicity in bacteria. Mutat. Res. 201, 127-136.
21. Dahl, T. A., W. R. Midden, and, P. E. Hartman, (1989) Comparison of killing of gram-negative and gram-positive bacteria by pure singlet oxygen. J. Bacteriology 171, 2188-2194.
22. Klotz, L.-O., C. Pellieux, K. Briviba, C. Pierlot, J.-M. Aubry, and, H. Sies, (1999) Mitogen-activated protein kinase (p38-, JNK-, ERK-) activation pattern induced by extracellular and intracellular singlet oxygen and UVA. Eur. J. Biochem. 260, 917-922.
23. Grether-Beck, S., S. Olaizola-Horn, H. Schmitt, M. Grewe, A. Jahnke, J. P. Johnson, K. Briviba, H. Sies, and, J. Krutmann, (1996) Activation of transcription factor AP-2 mediates UVA radiation- and singlet oxygen-induced expression of the human intercellular adhesion molecule 1 gene. Proc. Natl. Acad. Sci. USA 93, 14586-14591.
24. Steinbeck, M. J., A. U. Khan, and, M. J. Karnovsky, (1993) Extracellular production of singlet oxygen by stimulated macrophages quantified using 9,10-diphenylanthracene and perylene in a polystyrene film. J. Biol. Chem. 268, 15649-15654.
25. Tarr, M., and, D. P. Valenzeno, (2003) Singlet oxygen: The relevance of extracellular production mechanisms to oxidative stress in vivo. Photochem. Photobiol. Sci. 2, 355-361.
26. Dahl, T. A., (1993) Direct exposure of mammalian cells to pure exogenous singlet oxygen. Photochem. Photobiol. 57, 248-254.
27. Niedre, M., M. S. Patterson, and, B. C. Wilson, (2002) Direct near-infrared luminescence detection of singlet oxygen generated by photodynamic therapy in cells in vitro and tissues in vivo. Photochem. Photobiol. 75, 382-391.
28. Skovsen, E., J. W. Snyder, J. D. C. Lambert, and, P. R. Ogilby, (2005) Lifetime and diffusion of singlet oxygen in a cell. J. Phys. Chem. B 109, 8570-8573.
29. Snyder, J. W., E. Skovsen, J. D. C. Lambert, and, P. R. Ogilby, (2005) Subcellular, time-resolved studies of singlet oxygen in single cells. J. Am. Chem. Soc. 127, 14558-14559.
30. Breitenbach, T., P. R. Ogilby, and, J. D. C. Lambert, (2010) Effect of intracellular photosensitized singlet oxygen production on the electrophysiological properties of cultured rat hippocampal neurons. Photochem. Photobiol. Sci. 9, 1621-1633.
31. Alberts, B., A. Johnson, J. Lewis, M. Raff, K. Roberts, and, P. Walter, (2002) Molecular Biology of the Cell. Garland Science, New York.
32. Jarvi, M. T., M. J. Niedre, M. S. Patterson, and, B. C. Wilson, (2006) Singlet oxygen luminescence dosimetry (sold) for photodynamic therapy: Current status, challenges and future prospects. Photochem. Photobiol. 82, 1198-1210.
33. Snyder, J. W., J. D. C. Lambert, and, P. R. Ogilby, (2006) 5,10,15,20-Tetrakis(N-Methyl-4-Pyridyl)-21H,23H-Porphine (TMPyP) as a sensitizer for singlet oxygen imaging in cells: Characterizing the irradiation-dependent behavior of TMPyP in a single cell. Photochem. Photobiol. 82, 177-184.
34. Pedersen, B. W., T. Breitenbach, R. W. Redmond, and, P. R. Ogilby, (2010) Two-photon irradiation of an intracellular singlet oxygen photosensitizer: Achieving localized subcellular excitation in spatially-resolved experiments. Free Radic. Res. 44, 1383-1397.
35. Lebedev, A. Y., A. V. Cheprakov, S. Sakadzic, D. A. Boas, D. F. Wilson, and, S. A. Vinogradov, (2009) Dendritic phosphorescent probes for oxygen imaging in biological systems. ACS Appl. Mat. Inter. 1, 1292-1304.
36. Hatz, S., J. D. C. Lambert, and, P. R. Ogilby, (2007) Measuring the lifetime of singlet oxygen in a single cell: Addressing the issue of cell viability. Photochem. Photobiol. Sci. 6, 1106-1116.
37. Skovsen, E., J. W. Snyder, and, P. R. Ogilby, (2006) Two-photon singlet oxygen microscopy: The challenges of working with single cells. Photochem. Photobiol. 82, 1187-1197.
38. Arnbjerg, J., M. Johnsen, P. K. Frederiksen, S. E. Braslavsky, and, P. R. Ogilby, (2006) Two-photon photosensitized production of singlet oxygen: Optical and optoacoustic characterization of absolute two-photon absorption cross sections for standard sensitizers in different solvents. J. Phys. Chem. A 110, 7375-7385.
39. Breitenbach, T., M. K. Kuimova, P. Gbur, S. Hatz, N. B. Schack, B. W. Pedersen, J. D. C. Lambert, L. Poulsen, and, P. R. Ogilby, (2009) Photosensitized production of singlet oxygen: Spatially-resolved optical studies in single cells. Photochem. Photobiol. Sci. 8, 442-452.
40. Rello, S., J. C. Stockert, V. Moreno, A. Gámez, M. Pacheco, A. Juarranz, M. Cańete, and, A. Villanueva, (2005) Morphological criteria to distinguish cell death induced by apoptotic and necrotic treatments. Apoptosis 10, 201-208.
41. Häcker, G., (2000) The morphology of apoptosis. Cell Tissue Res. 301, 5-17.
42. Johnson, I. D., (2006) Practical considerations in the selection and application of fluorescent probes. In Handbook of Biological Confocal Microscopy (Edited by, J. B. Pawley,), pp. 353-367. Springer, New York.
43. g). J. Phys. Chem. 99, 3521-3526.
44. Frederiksen, P. K., S. P. McIlroy, C. B. Nielsen, L. Nikolajsen, E. Skovsen, M. Jǒrgensen, K. V. Mikkelsen, and, P. R. Ogilby, (2005) Two-photon photosensitized production of singlet oxygen in water. J. Am. Chem. Soc. 127, 255-269.
45. Dunphy, I., S. A. Vinogradov, and, D. F. Wilson, (2002) Oxyphor R2 and G2: Phosphors for measuring oxygen by oxygen-dependent quenching of phosphorescence. Anal. Biochem. 310, 191-198.
46. Rietveld, I. B., E. Kim, and, S. A. Vinogradov, (2003) Dendrimers with tetrabenzoporphyrin cores: Near infrared phosphors for in vivo oxygen imaging. Tetrahedron 59, 3821-3831.
47. Vinogradov, S. A., L.-W. Lo, and, D. F. Wilson, (1999) Dendritic polyglutamic porphyrins: Probing porphyrin protection by oxygen-dependent quenching of phosphorescence. Chem. Eur. J. 5, 1338-1347.
48. Vinogradov, S. A., and, D. F. Wilson, (2000) Electrostatic core shielding in dendritic polyglutamic porphyrins. Chem. Eur. J. 6, 2456-2461.
49. Vanderkooi, J. M., G. Maniara, T. J. Green, and, D. F. Wilson, (1987) An optical method for measurement of dioxygen concentration based upon quenching of phosphorescence. J. Biol. Chem. 262, 5476-5482.
50. Spiller, D. G., C. D. Wood, D. A. Rand, and, M. R. H. White, (2010) Measurement of single-cell dynamics. Nature 465, 736-745.
51. Rozhkov, V., D. Wilson, and, S. Vinogradov, (2002) Phosphorescent Pd porphyrin dendrimers: Tuning core accessibility by varying the hydrophobicity of the dendritic matrix. Macromolecules 35, 1991-1993.
52. Finikova, O. S., A. Y. Lebedev, A. Aprelev, T. Troxler, F. Gao, C. Garnacho, S. Muro, R. M. Hochstrasser, and, S. A. Vinogradov, (2008) Oxygen microscopy by two-photon-excited phosphorescence. Chemphyschem 9, 1673-1679.
53. Hess, S. T., and, W. W. Webb, (2002) Focal volume optics and experimental artifacts in confocal fluorescence correlation spectroscopy. Biophys. J. 83, 2300-2317.
54. Backman, V., V. Gopal, M. Kalashnikov, K. Badizadegan, R. Gurjar, A. Wax, I. Georgakoudi, M. Mueller, C. W. Boone, R. R. Dasari, and, M. S. Feld, (2001) Measuring cellular structure at submicrometer scale with light scattering spectroscopy. IEEE J. Sel. Top. Quantum Electron. 7, 887-893.
55. Sims, C. E., G. D. Meredith, T. B. Krasieva, M. W. Berns, B. J. Tromberg, and, N. L. Allbritton, (1998) Laser micropipet combination for single-cell analysis. Anal. Chem. 70, 4570-4577.
56. Soughayer, J. S., T. Krasieva, S. C. Jacobson, J. M. Ramsey, B. J. Tromberg, and, N. L. Allbritton, (2000) Characetrization of cellular optoporation with distance. Anal. Chem. 72, 1342-1347.
57. Schneckenburger, H., A. Hendinger, R. Sailer, W. S. L. Strauss, and, M. Schmitt, (2002) Laser-assisted optoporation of single cells. J. Biomed. Optics 7, 410-416.
58. Wilkinson, F., W. P. Helman, and, A. B. Ross, (1995) Rate constants for the decay and reactions of the lowest electronically excited singlet state of molecular oxygen in solution. An expanded and revised compilation. J. Phys. Chem. Ref. Data 24, 663-1021.
59. Kuimova, M. K., G. Yahioglu, and, P. R. Ogilby, (2009) Singlet oxygen in a cell: Spatially dependent lifetimes and quenching rate constants. J. Am. Chem. Soc. 131, 332-340.
60. Halliwell, B., and, J. M. C. Gutteridge, (1999) Free Radicals in Biology and Medicine. Oxford University Press, Oxford.
61. O'Donnell-Tormey, J., C. F. Nathan, K. Lanks, C. J. DeBoer, and, J. de la Harpe, (1987) Secretion of pyruvate: An antioxidant defense of mammalian cells. J. Exp. Med. 165, 500-514.
62. Franco, R., M. I. Panaylotidis, and, J. A. Cidlowski, (2007) Glutathione depletion is necessary for apoptosis in lymphoid cells independent of reactive oxygen species formation. J. Biol. Chem. 282, 30452-30465.
63. Schweitzer, C., and, R. Schmidt, (2003) Physical mechanisms of generation and deactivation of singlet oxygen. Chem. Rev. 103, 1685-1757.
64. Ogilby, P. R., and, C. S. Foote, (1983) The effect of solvent, solvent isotopic substitution, and temperature on the lifetime of singlet molecular oxygen. J. Am. Chem. Soc. 105, 3423-3430.
65. Egorov, S. Y., V. F. Kamalov, N. I. Koroteev, A. A. Krasnovsky, B. N. Toleutaev, and, S. V. Zinukov, (1989) Rise and decay kinetics of photosensitized singlet oxygen luminescence in water. Measurements with nanosecond time-correlated single photon counting technique. Chem. Phys. Lett. 163, 421-424.