Singlet Oxygen Luminescence Dosimetry (SOLD) for photodynamic therapy: Current status, challenges and future prospects

Photochemistry and Photobiology

Volumn 82, Issue 5, 2006, Pages 1198-1210

  Jarvi, Mark T ^a   Niedre, Mark J ^a   Patterson, Michael S ^b   Wilson, Brian C ^a  

^a UNIVERSITY OF TORONTO   (Canada)

^b MCMASTER UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

SINGLET OXYGEN;

ANIMAL; CONFERENCE PAPER; DISEASE MODEL; EXPERIMENTAL NEOPLASM; HUMAN; INSTRUMENTATION; LUMINESCENCE; METHODOLOGY; PHOTOCHEMOTHERAPY;

ANIMALS; DISEASE MODELS, ANIMAL; HUMANS; LUMINESCENCE; LUMINESCENT MEASUREMENTS; NEOPLASMS, EXPERIMENTAL; PHOTOCHEMOTHERAPY; SINGLET OXYGEN;

EID: 33750705279     PISSN: 00318655     EISSN: None     Source Type: Journal    
DOI: 10.1562/2006-05-03-IR-891     Document Type: Conference Paper

References (72)

1. Kendall, C. A. and C. A. Morton (2003) Photodynamic therapy for the treatment of skin disease. Technol. Cancer Res. Treat. 2, 283-288.
2. Brown, S. B., E. A. Brown and I. Walker (2004) The present and future role of photodynamic therapy in cancer treatment. Lancet Oncol. 5, 49,7-508.
3. Dougherty, T. J. (2002) An update on photodynamic therapy applications. J. Clin. Laser Med. Surg. 20, 3-7.
4. Demidova, T. N. and M. R. Hamblin (2004) Photodynamic therapy targeted to pathogens. Int. J. Immunopathol. Pharmacol. 17, 245-254.
5. Weersink, R. A., A. Bogaards, M. Gertner, S. R. Davidson, K. Zhang, G. Netchev, J. Trachtenberg and B. C. Wilson (2005) Techniques for delivery and monitoring of TOOKAD (WST09)-mediated photodynamic therapy of the prostate: Clinical experience and practicalities. J. Photochem. Photobiol. B 79, 211-222.
6. Thompson, M. S., A. Johansson, T. Johansson, S. Andersson-Engels, S. Svanberg, N. Bendsoe and K. Svanberg (2005) Clinical system for interstitial photodynamic therapy with combined on-line dosimetry measurements. Appl. Opt. 44, 4023-4031.
7. Zhou, X., B. W. Pogue, B. Chen, E. Demidenko, R. Joshi, J. Hoopes and T. Hasan (2006) Pretreatment photosensitizer dosimetry reduces variation in tumor response. Int. J. Radiat. Oncol. Biol. Phys. 64, 1211-1220.
8. Wilson, B. C., M. S. Patterson and L. Lilge (1997) Implicit and explicit dosimetry in photodynamic therapy: A new paradigm. Lasers Med. Sci. 12, 182-199.
9. Zhu, T. C., J. C. Finlay and S. M. Hahn (2005) Determination of the distribution of light, optical properties, drug concentration, and tissue oxygenation in-vivo in human prostate during motexafin lutetium-mediated photodynamic therapy. J. Photochem. Photobiol. B 79, 231-241.
10. Zeng, H., M. Korbelik, D. I. McLean, C. MacAulay and H. Lui (2002) Monitoring photoproduct formation and photobleaching by fluorescence spectroscopy has the potential to improve PDT dosimetry with a verteporfin-like photosensitizer. Photochem. Photobiol. 75, 398-405.
11. Georgakoudi, I., M. G. Nichols and T. H. Foster (1997) The mechanism of Photofrin photobleaching and its consequences for photodynamic dosimetry. Photochem. Photobiol. 65, 135-144.
12. Robinson, D. J., H. S. de Bruijn, N. van der Veen, M. R. Stringer, S. B. Brown and W. M. Star (1998) Fluorescence photobleaching of ALA-induced protoporphyrin IX during photodynamic therapy of normal hairless mouse skin: The effect of light dose and irradiance and the resulting biological effect. Photochem. Photobiol. 67, 140-149.
13. Dysart, J. S., G. Singh and M. S. Patterson (2005) Calculation of singlet oxygen dose from photosensitizer fluorescence and photobleaching during mTHPC photodynamic therapy of MLL cells. Photochem. Photobiol. 81, 196-205.
14. Dysart, J. S. and M. S. Patterson (2006) Photobleaching kinetics, photoproduct formation, and dose estimation during ALA induced PpIX PDT of MLL cells under well oxygenated and hypoxic conditions. Photochem. Photobiol. Sci. 5, 73-81.
15. Molckovsky, A. and B. C. Wilson (2001) Monitoring of cell and tissue responses to photodynamic therapy by electrical impedance spectroscopy. Phys. Med. Biol. 46, 983-1002.
16. Chen, B., B. W. Pogue, I. A. Goodwin, J. A. O'Hara, C. M. Wilmot, J. E. Hutchins, P. J. Hoopes and T. Hasan (2003) Blood flow dynamics after photodynamic therapy with verteporfin in the RIF-1 tumor. Radiat. Res. 160, 452-459.
17. Yu, G., T. Durduran, C. Zhou, H. W. Wang, M. E. Putt, H. M. Saunders, C. M. Sehgal, E. Glatstein, A. G. Yodh and T. M. Busch (2005) Noninvasive monitoring of murine tumor blood flow during and after photodynamic therapy provides early assessment of therapeutic efficacy. Clin. Cancer Res. 11, 3543-3552.
18. Gordon, M., V. Yang, E. Yue, S. Lo, B. Wilson and I. Vitkin (2004) Doppler optical coherence tomography for monitoring the vascular effects of photodynamic therapy. In Proc. SPIE, 5316, 147-154. SPIE, Bellingham, WA.
19. Lapointe, D., N. Brasseur, J. Cadorette, C. La Madeleine, S. Rodrigue, J. E. van Lier and R. Lecomte (1999) High-resolution PET imaging for in vivo monitoring of tumor response after photodynamic therapy in mice. J. Nucl. Med. 40, 876-882.
20. Patterson, M. S., S. J. Madsen and B. C. Wilson (1990) Experimental tests of the feasibility of singlet oxygen luminescence monitoring in vivo during photodynamic therapy. J. Photochem. Photobiol. B 5, 69-84.
21. Chou, P. T., Y. C. Chen, C. Y. Wei and M. Z. Lee (1998) Evidence on the O-2((1)Delta(g)) dimol-sensitized luminescence in solution. J. Am. Chem. Soc 120, 4883-4884.
22. Snyder, J. W., I. Zebger, Z. Gao, L. Poulsen, P. K. Frederiksen, E. Skovsen, S. P. McIlroy, M. Klinger, L. K. Andersen and P. R. Ogilby (2004) Singlet oxygen microscope: From phase-separated polymers to single biological cells. Acc. Chem. Res. 37, 894-901.
23. Schmidt, R. and M. Bodesheim (1994) Time-resolved measurement of O2((1)sigma(G)+) in solution - phosphorescence from an upper excited-state. J. Phys. Chem. 98, 2874-2876.
24. Khan, A. U. (1980) Direct spectroscopic observation of 1.27 mu-M and 1.58 mu-M emission of singlet (1-delta-G) molecular-oxygen in chemically generated and dye-photosensitized liquid solutions at room-temperature. Chem. Phys. Lett. 72, 112-114.
25. Qin, Y., D. Xing, S. Luo, J. Zhou, X. Zhong and Q. Chen (2005) Feasibility of using fluoresceinyl Cypridina luciferin analog in a novel chemiluminescence method for real-time photodynamic therapy dosimetry. Photochem. Photobiol. 81, 1534-1538.
26. Zang, L. Y., Z. Y. Zhang and H. P. Misra (1990) EPR studies of trapped singlet oxygen (1O2) generated during photoirradiation of hypocrellin A. Photochem. Photobiol. 52, 677-683.
27. Weishaupt, K. R., C. J. Gomer and T. J. Dougherty (1976) Identification of singlet oxygen as the cytotoxic agent in photoinactivation of a murine tumor. Cancer Res. 36, 2326-2329.
28. Krasnovskii, A. A. (1976) Photosensitized luminescence of singlet oxygen in solution. Biofizika 21, 748-749.
29. Khan, A. U. and M. Kasha (1979) Direct spectroscopic observation of singlet oxygen emission at 1268 nm excited by sensitizing dyes of biological interest in liquid solution. Proc. Natl. Acad. Sci. USA 76, 6047-6049.
30. Firey, P. A., T. W. Jones, G. Jori and M. A. J. Rodgers (1988) Photoexcitation of zinc phthalocyanine in mouse myeloma cells: The observation of triplet states but not of singlet oxygen. Photochem. Photobiol. 48, 357-360.
31. Truscott, T. G., A. J. McLean, A. M. Phillips and W. S. Foulds (1988) Detection of haematoporphyrin derivative and haematoporphyrin excited states in cell environments. Cancer Lett. 41, 31-35.
32. Firey, P. A. and M. A. J. Rodgers (1988) Photochemical properties of erythrocyte-ghosts containing porphyrin. Photochem. Photobiol. 47, 615-619.
33. Baker, A. and J. R. Kanofsky (1991) Direct observation of singlet oxygen phosphorescence at 1270 nm from Ll210 leukemia cells exposed to polyporphyrin and light. Arch. Biochem. Biophys. 286, 70-75.
34. Oelckers, S., T. Ziegler, I. Michler, and B. Roder (1999) Time-resolved detection of singlet oxygen luminescence in red-cell ghost suspensions: Concerning a signal component that can be attributed to 1O2 luminescence from the inside of a native membrane. J. Photochem. Photobiol. B 53, 121-127.
35. Thomas, J. P., R. D. Hall and A. W. Girotti (1987) Singlet oxygen intermediacy in the photodynamic action of membrane-bound hematoporphyrin derivative. Cancer Lett. 35, 295-302.
36. Krasnovsky, A. A., Jr. (1998) Singlet molecular oxygen in photobiochemical systems: IR phosphorescence studies. Membr. Cell Biol. 12, 665-690.
37. Parker, J. G. (1987) Optical monitoring of singlet oxygen generation during photodynamic treatment of tumors. IEEE Circuit Devices 3, 10-21.
38. Schweitzer, C. and R. Schmidt (2003) Physical mechanisms of generation and deactivation of singlet oxygen. Chem. Rev. 103, 1685-1757.
39. Niedre, M., M. S. Patterson and B. C. Wilson (2002) Direct near-infrared luminescence detection of singlet oxygen generated by photodynamic therapy in cells in vitro and tissues in vivo. Photochem. Photobiol. 75, 382-391.
40. Nonell, S. and S. E. Braslavsky (2000) Time-resolved singlet oxygen detection. Methods Enzymol. 319, 37-49.
41. Gorman, A. A. and M. A. Rodgers (1992) Current perspectives of singlet oxygen detection in biological environments. J. Photochem. Photobiol. B 14, 159-176.
42. Hirano, T., E. Kohno and M. Nishiwaki (2002) Detection of near infrared emission from singlet oxygen in PDT with an experimental tumor bearing mouse. J. Jpn. Soc. Laser Surg. Med. 22, 99-108.
43. Niedre, M. J., A. J. Secord, M. S. Patterson and B. C. Wilson (2003) In vitro tests of the validity of singlet oxygen luminescence measurements as a dose metric in photodynamic therapy. Cancer Res. 63, 7986-7994.
44. Niedre, M. J., C. S. Yu, M. S. Patterson and B. C. Wilson (2005) Singlet oxygen luminescence as an in vivo photodynamic therapy dose metric: Validation in normal mouse skin with topical amino-levulinic acid. Br. J. Cancer 92, 298-304.
45. Coutier, S., L. N. Bezdetnaya, T. H. Foster, R. M. Parache and F. Guillemin (2002) Effect of irradiation fluence rate on the efficacy of photodynamic therapy and tumor oxygenation in meta-tetra (hydroxyphenyl) chlorin (mTHPC)-sensitized HT29 xenografts in nude mice. Radiat. Res. 158, 339-345.
46. Shonat, R. D. and A. C. Kight (2003) Oxygen tension imaging in the mouse retina. Ann. Biomed. Eng. 31, 1084-1096.
47. Poole, D. C., B. J. Behnke, P. McDonough, R. M. McAllister and D. F. Wilson (2004) Measurement of muscle microvascular oxygen pressures: Compartmentalization of phosphorescent probe. Microcirculation 11, 317-326.
48. Niedre, M. J., M. S. Patterson, A. Giles and B. C. Wilson (2005) Imaging of photodynamically generated singlet oxygen luminescence in vivo. Photochem. Photobiol. 81, 941-943.
49. Snyder, J. W., J. D. Lambert and P. R. Ogilby (2006) 5,10,15, 20-tetrakis(N-methyl-4-pyridyl)-21H,23H-porphine (TMPyP) as a sensitizer for singlet oxygen imaging in cells: Characterizing the irradiation-dependent behavior of TMPyP in a single cell. Photochem. Photobiol. 82, 177-184.
50. Skovsen, E., J. W. Snyder, J. D. C. Lambert, and P. R. Ogilby (2005) Lifetime and diffusion of singlet oxygen in a cell. J. Phys. Chem. B 109, 8570-8573.
51. Frederiksen, P. K., S. P. McIlroy, C. B. Nielsen, L. Nikolajsen, E. Skovsen, M. Jorgensen, K. V. Mikkelsen and P. R. Ogilby (2005) Two-photon photosensitized production of singlet oxygen in water. J. Am. Chem. Soc. 127, 255-269.
52. Davis, S., L. Zhu, A. Minhaj, D. Rosen, P. Keeling and T. Hasan (2003). Ultra-sensitive, diode laser based monitor for singlet oxygen. In Proc. SPIE, 4952, 140-148. SPIE, Bellingham, WA.
53. Lee, S., L. Zhu, A. Minhaj, M. Hinds, A. Ferrante, D. Vu, D. Rosen and S. Davis. Diode laser monitor for singlet molecular oxygen. In Proc. SPIE. 5689, 90-96. SPIE, Bellingham, WA.
54. Baier, A., M. Maier, R. Engl, M. Landthaler and W. Baumler (2005) Time-resolved investigations of singlet oxygen luminescence in water, in phosphatidylcholine, and in aqueous suspensions of phosphatidylcholine or HT29 cells. J. Phys. Chem. B 109, 3041-3046.
55. Butorina, D. N., A. A. Krasnovskii and A. V. Priezzhev (2003) Study of kinetic parameters of singlet molecular oxygen in aqueous porphyrin solutions. Effect of detergents and the quencher sodium azide. Biofizika 48, 201-209.
56. Cova, S., M. Ghioni, A. Lotito, I. Rech and F. Zappa (2004) Evolution and prospects for single-photon avalanche diodes and quenching circuits. J. Mod. Opt. 51, 1267-1288.
57. Korneev, A., V. Matvienko, O. Minaeva, I. Milostnaya, I. Rubtsova, G. Chulkova, K. Smirnov, V. Voronov, G. Gol'tsman, W. Slysz, A. Pearlman, A. Verevkin and R. Sobolewski (2005) Quantum efficiency and noise equivalent power of nanostructured, NbN, single-photon detectors in the wavelength range from visible to infrared. IEEE Trans. Appl. Supercond. 15, 571-574.
58. Konig, K., H. Schneckenburger, A. Ruck and R. Steiner (1993) In vivo photoproduct formation during PDT with ALA-induced endogenous porphyrins. J. Photochem. Photobiol. B 18, 287-290.
59. Kress, M., T. Meier, R. Steiner, F. Dolp, R. Erdmann, U. Ortmann and A. Ruck (2003) Time-resolved microspectrofluorometry and fluorescence lifetime imaging of photosensitizers using picosecond pulsed diode lasers in laser scanning microscopes. J. Biomed. Opt. 8, 26-32.
60. Foster, T. H., B. D. Pearson, S. Mitra and C. E. Bigelow (2005) Fluorescence anisotropy imaging reveals localization of mesotetrahydroxyphenyl chlorin in the nuclear envelope. Photochem. Photobiol. 81, 1544-1547.
61. Martinez, L. A., C. G. Martinez, B. B. Klopotek, J. Lang, A. Neuner, A. M. Braun and E. Oliveros (2000) Nonradiative and radiative deactivation of singlet molecular oxygen (O-2(a(1)Delta(g))) in micellar media and microemulsions. J. Photochem. Photobiol. B 58, 94-107.
62. Snyder, J. W., E. Skovsen, J. D. Lambert and P. R. Ogilby (2005) Subcellular, time-resolved studies of singlet oxygen in single cells. J. Am. Chem. Soc. 127, 14558-14559.
63. Sterenborg, H., J. W. de Wolf, M. Koning, B. Kruijt, A. van den Heuvel and D. J. Robinson (2004) Phosphorescence-fluorescence ratio imaging for monitoring the oxygen status during photodynamic therapy. Opt. Express 12, 1873-1878.
64. Gibson, A. P., J. C. Hebden and S. R. Arridge (2005) Recent advances in diffuse optical imaging. Phys. Med. Biol. 50, R1-43.
65. Henderson, B. W., S. M. Waldow, T. S. Mang, W. R. Potter, P. B. Malone and T. J. Dougherty (1985) Tumor destruction and kinetics of tumor cell death in two experimental mouse tumors following photodynamic therapy. Cancer Res. 45, 572-576.
66. Karotki, A., M. Khurana, J. R. Lepock and B. C. Wilson (2006) Simultaneous two-photon excitation of photofrin in relation to photodynamic therapy. Photochem. Photobiol. 82, 443-452.
67. Samkoe, K. S. and D. T. Cramb (2003) Application of an ex ovo chicken chorioallantoic membrane model for two-photon excitation photodynamic therapy of age-related macular degeneration. J. Biomed. Opt. 8, 410-417.
68. Spangler, C., J. Starkey, A. Rebane, F. Meng, A. Gong and M. Drobizhev. Synthesis, characterization, and preclinical studies of two-photon-activated targeted PDT therapeutic triads. In Proc. SPIE, 6139, 219-228. SPIE, Bellingham, WA.
69. Paul, A., A. Molich, S. Oelckers, M. Seifert and B. Roder (2002) Alkyl-substituted magnesium phthalocyanine: Phototoxicity after excitation of higher electronic states in cells in vitro. J. Porphyrins Phthalocyanines 6, 340-346.
70. Smith, G., W. G. McGimpsey, M. C. Lynch, I. E. Kochevar and R. W. Redmond (1994) An efficient oxygen independent two-photon photosensitization mechanism. Photochem. Photobiol. 59, 135-139.
71. Chen, J., K. Stefflova, M. J. Niedre, B. C. Wilson, B. Chance, J. D. Glickson and G. Zheng (2004) Protease-triggered photosensitizing beacon based on singlet oxygen quenching and activation. J. Am. Chem. Soc. 126, 11450-11451.
72. Clo, E., J. W. Snyder, N. V. Voigt, P. R. Ogilby and K. V. Gothelf (2006) DNA-programmed control of photosensitized singlet oxygen production. J. Am. Chem. Soc. 128, 4200-4201.