메뉴 건너뛰기




Volumn 6, Issue 9, 2011, Pages

An updated meta-analysis of endothelial nitric oxide synthase gene: Three well-characterized polymorphisms with hypertension

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; ASIAN; CHINESE; CONTROLLED STUDY; DATA ANALYSIS SOFTWARE; ENDOTHELIAL NITRIC OXIDE SYNTHASE GENE; ETHNICITY; GENE; GENE FREQUENCY; GENE FUNCTION; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC RISK; GENETIC VARIABILITY; HIGH RISK POPULATION; HUMAN; HYPERTENSION; MAJOR CLINICAL STUDY; META ANALYSIS (TOPIC); PROMOTER REGION; PUBLICATION; RISK ASSESSMENT; EXON; FEMALE; GENETICS; INTRON; MALE; META ANALYSIS; MIDDLE AGED;

EID: 80052423663     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0024266     Document Type: Article
Times cited : (64)

References (55)
  • 1
    • 0005003318 scopus 로고
    • Are there interactions and relations between genetic and environmental factors predisposing to high blood pressure?
    • Williams RR, Hunt SC, Hasstedt SJ, Hopkins PN, Wu LL, et al. (1991) Are there interactions and relations between genetic and environmental factors predisposing to high blood pressure? Hypertension 18: I29-I37.
    • (1991) Hypertension , vol.18
    • Williams, R.R.1    Hunt, S.C.2    Hasstedt, S.J.3    Hopkins, P.N.4    Wu, L.L.5
  • 2
    • 77955851660 scopus 로고    scopus 로고
    • Validation of genetic association in apelin-AGTRL1 system with hypertension in a larger Han Chinese population
    • Niu W, Wu S, Zhang Y, Li W, Ji K, et al. (2010) Validation of genetic association in apelin-AGTRL1 system with hypertension in a larger Han Chinese population. J Hypertens 28: 1854-1861.
    • (2010) J Hypertens , vol.28 , pp. 1854-1861
    • Niu, W.1    Wu, S.2    Zhang, Y.3    Li, W.4    Ji, K.5
  • 3
    • 71549156556 scopus 로고    scopus 로고
    • Endothelium-specific overexpression of human IC53 downregulates endothelial nitric oxide synthase activity and elevates systolic blood pressure in mice
    • Zhuo ML, Huang Y, Chen JZ, Sun LH, Yang RF, et al. (2009) Endothelium-specific overexpression of human IC53 downregulates endothelial nitric oxide synthase activity and elevates systolic blood pressure in mice. Cardiovasc Res 84: 292-299.
    • (2009) Cardiovasc Res , vol.84 , pp. 292-299
    • Zhuo, M.L.1    Huang, Y.2    Chen, J.Z.3    Sun, L.H.4    Yang, R.F.5
  • 4
    • 0029021148 scopus 로고
    • Hypertension in mice lacking the gene for endothelial nitric oxide synthase
    • Huang PL, Huang Z, Mashimo H, Bloch KD, Moskowitz MA, et al. (1995) Hypertension in mice lacking the gene for endothelial nitric oxide synthase. Nature 377: 239-242.
    • (1995) Nature , vol.377 , pp. 239-242
    • Huang, P.L.1    Huang, Z.2    Mashimo, H.3    Bloch, K.D.4    Moskowitz, M.A.5
  • 5
    • 0032535435 scopus 로고    scopus 로고
    • Hypotension and reduced nitric oxide-elicited vasorelaxation in transgenic mice overexpressing endothelial nitric oxide synthase
    • Ohashi Y, Kawashima S, Hirata K, Yamashita T, Ishida T, et al. (1998) Hypotension and reduced nitric oxide-elicited vasorelaxation in transgenic mice overexpressing endothelial nitric oxide synthase. J Clin Invest 102: 2061-2071.
    • (1998) J Clin Invest , vol.102 , pp. 2061-2071
    • Ohashi, Y.1    Kawashima, S.2    Hirata, K.3    Yamashita, T.4    Ishida, T.5
  • 8
    • 0031902667 scopus 로고    scopus 로고
    • Endothelial nitric oxide synthase gene is positively associated with essential hypertension
    • Miyamoto Y, Saito Y, Kajiyama N, Yoshimura M, Shimasaki Y, et al. (1998) Endothelial nitric oxide synthase gene is positively associated with essential hypertension. Hypertension 32: 3-8.
    • (1998) Hypertension , vol.32 , pp. 3-8
    • Miyamoto, Y.1    Saito, Y.2    Kajiyama, N.3    Yoshimura, M.4    Shimasaki, Y.5
  • 9
    • 0031916030 scopus 로고    scopus 로고
    • Nitric oxide synthase gene polymorphisms, blood pressure and aortic stiffness in normotensive and hypertensive subjects
    • Lacolley P, Gautier S, Poirier O, Pannier B, Cambien F, et al. (1998) Nitric oxide synthase gene polymorphisms, blood pressure and aortic stiffness in normotensive and hypertensive subjects. J Hypertens 16: 31-35.
    • (1998) J Hypertens , vol.16 , pp. 31-35
    • Lacolley, P.1    Gautier, S.2    Poirier, O.3    Pannier, B.4    Cambien, F.5
  • 10
    • 0032890548 scopus 로고    scopus 로고
    • Lack of evidence for association between the endothelial nitric oxide synthase gene and hypertension
    • Kato N, Sugiyama T, Morita H, Nabika T, Kurihara H, et al. (1999) Lack of evidence for association between the endothelial nitric oxide synthase gene and hypertension. Hypertension 33: 933-936.
    • (1999) Hypertension , vol.33 , pp. 933-936
    • Kato, N.1    Sugiyama, T.2    Morita, H.3    Nabika, T.4    Kurihara, H.5
  • 11
    • 0031918997 scopus 로고    scopus 로고
    • Association of a variable number of tandem repeats in the endothelial constitutive nitric oxide synthase gene with essential hypertension in Japanese
    • Uwabo J, Soma M, Nakayama T, Kanmatsuse K, (1998) Association of a variable number of tandem repeats in the endothelial constitutive nitric oxide synthase gene with essential hypertension in Japanese. Am J Hypertens 11: 125-128.
    • (1998) Am J Hypertens , vol.11 , pp. 125-128
    • Uwabo, J.1    Soma, M.2    Nakayama, T.3    Kanmatsuse, K.4
  • 12
    • 0033863842 scopus 로고    scopus 로고
    • Association analyses of endothelial nitric oxide synthase gene polymorphisms in essential hypertension
    • Benjafield AV, Morris BJ, (2000) Association analyses of endothelial nitric oxide synthase gene polymorphisms in essential hypertension. Am J Hypertens 13: 994-998.
    • (2000) Am J Hypertens , vol.13 , pp. 994-998
    • Benjafield, A.V.1    Morris, B.J.2
  • 13
    • 0012266389 scopus 로고    scopus 로고
    • Positive association of endothelial nitric oxide synthase gene polymorphism with hypertension in northern Japan
    • Shoji M, Tsutaya S, Saito R, Takamatu H, Yasujima M, (2000) Positive association of endothelial nitric oxide synthase gene polymorphism with hypertension in northern Japan. Life Sci 66: 2557-2562.
    • (2000) Life Sci , vol.66 , pp. 2557-2562
    • Shoji, M.1    Tsutaya, S.2    Saito, R.3    Takamatu, H.4    Yasujima, M.5
  • 14
    • 0034536746 scopus 로고    scopus 로고
    • Lack of association between T-786->C mutation in the 5′-flanking region of the endothelial nitric oxide synthase gene and essential hypertension
    • Kajiyama N, Saito Y, Miyamoto Y, Yoshimura M, Nakayama M, et al. (2000) Lack of association between T-786->C mutation in the 5′-flanking region of the endothelial nitric oxide synthase gene and essential hypertension. Hypertens Res 23: 561-565.
    • (2000) Hypertens Res , vol.23 , pp. 561-565
    • Kajiyama, N.1    Saito, Y.2    Miyamoto, Y.3    Yoshimura, M.4    Nakayama, M.5
  • 15
    • 0034775272 scopus 로고    scopus 로고
    • Combined effects of endothelial nitric oxide synthase gene polymorphism (G894T) and insulin resistance status on blood pressure and familial risk of hypertension in young adults: the Bogalusa Heart Study
    • Chen W, Srinivasan SR, Elkasabany A, Ellsworth DL, Boerwinkle E, Berenson GS, (2001) Combined effects of endothelial nitric oxide synthase gene polymorphism (G894T) and insulin resistance status on blood pressure and familial risk of hypertension in young adults: the Bogalusa Heart Study. Am J Hypertens 14: 1046-1052.
    • (2001) Am J Hypertens , vol.14 , pp. 1046-1052
    • Chen, W.1    Srinivasan, S.R.2    Elkasabany, A.3    Ellsworth, D.L.4    Boerwinkle, E.5    Berenson, G.S.6
  • 16
    • 0034811586 scopus 로고    scopus 로고
    • Association of the Glu298Asp polymorphism in the endothelial nitric oxide synthase gene with essential hypertension resistant to conventional therapy
    • Jáchymová M, Horký K, Bultas J, Kozich V, Jindra A, et al. (2001) Association of the Glu298Asp polymorphism in the endothelial nitric oxide synthase gene with essential hypertension resistant to conventional therapy. Biochem Biophys Res Commun 284: 426-430.
    • (2001) Biochem Biophys Res Commun , vol.284 , pp. 426-430
    • Jáchymová, M.1    Horký, K.2    Bultas, J.3    Kozich, V.4    Jindra, A.5
  • 17
    • 0034768750 scopus 로고    scopus 로고
    • Association analyses between genetic polymorphisms of endothelial nitric oxide synthase gene and hypertension in Japanese: The Suita Study
    • Tsujita Y, Baba S, Yamauchi R, Mannami T, Kinoshita M, et al. (2001) Association analyses between genetic polymorphisms of endothelial nitric oxide synthase gene and hypertension in Japanese: The Suita Study. J Hypertens 19: 1941-1948.
    • (2001) J Hypertens , vol.19 , pp. 1941-1948
    • Tsujita, Y.1    Baba, S.2    Yamauchi, R.3    Mannami, T.4    Kinoshita, M.5
  • 18
    • 0035723769 scopus 로고    scopus 로고
    • Lack of association between polymorphisms of catalase, copper-zinc superoxide dismutase (SOD), extracellular SOD and endothelial nitric oxide synthase genes and macroangiopathy in patients with type 2 diabetes mellitus
    • Ukkola O, Erkkilä PH, Savolainen MJ, Kesäniemi YA, (2001) Lack of association between polymorphisms of catalase, copper-zinc superoxide dismutase (SOD), extracellular SOD and endothelial nitric oxide synthase genes and macroangiopathy in patients with type 2 diabetes mellitus. J Intern Med 249: 451-459.
    • (2001) J Intern Med , vol.249 , pp. 451-459
    • Ukkola, O.1    Erkkilä, P.H.2    Savolainen, M.J.3    Kesäniemi, Y.A.4
  • 19
    • 0036169224 scopus 로고    scopus 로고
    • Endothelial nitric oxide synthase gene Glu298Asp polymorphism and blood pressure, left ventricular mass and carotid artery atherosclerosis in a population-based cohort
    • Karvonen J, Kauma H, Kervinen K, Rantala M, Ikäheimo M, et al. (2002) Endothelial nitric oxide synthase gene Glu298Asp polymorphism and blood pressure, left ventricular mass and carotid artery atherosclerosis in a population-based cohort. J Intern Med 251: 102-110.
    • (2002) J Intern Med , vol.251 , pp. 102-110
    • Karvonen, J.1    Kauma, H.2    Kervinen, K.3    Rantala, M.4    Ikäheimo, M.5
  • 20
    • 0036010970 scopus 로고    scopus 로고
    • The T-786->C mutation in endothelial nitric oxide synthase is associated with hypertension
    • Hyndman ME, Parsons HG, Verma S, Bridge PJ, Edworthy S, et al. (2002) The T-786->C mutation in endothelial nitric oxide synthase is associated with hypertension. Hypertension 39: 919-922.
    • (2002) Hypertension , vol.39 , pp. 919-922
    • Hyndman, M.E.1    Parsons, H.G.2    Verma, S.3    Bridge, P.J.4    Edworthy, S.5
  • 21
    • 0348135040 scopus 로고    scopus 로고
    • Does endothelial nitric oxide synthase gene variation play a role in the occurrence of hypertension in pregnancy?
    • Grandone E, Colaizzo D, Martinelli P, Pavone G, Errico M, et al. (2003) Does endothelial nitric oxide synthase gene variation play a role in the occurrence of hypertension in pregnancy? Hypertens Pregnancy 22: 149-155.
    • (2003) Hypertens Pregnancy , vol.22 , pp. 149-155
    • Grandone, E.1    Colaizzo, D.2    Martinelli, P.3    Pavone, G.4    Errico, M.5
  • 22
    • 0042733636 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-gamma2-Pro12Ala and endothelial nitric oxide synthase-4a/bgene polymorphisms are associated with essential hypertension
    • Rodríguez-Esparragón FJ, Rodríguez-Pérez JC, Macías-Reyes A, Alamo-Santana F, (2003) Peroxisome proliferator-activated receptor-gamma2-Pro12Ala and endothelial nitric oxide synthase-4a/bgene polymorphisms are associated with essential hypertension. J Hypertens 21: 1649-1655.
    • (2003) J Hypertens , vol.21 , pp. 1649-1655
    • Rodríguez-Esparragón, F.J.1    Rodríguez-Pérez, J.C.2    Macías-Reyes, A.3    Alamo-Santana, F.4
  • 23
    • 0037454141 scopus 로고    scopus 로고
    • The T-786C and Glu298Asp polymorphisms of the endothelial nitric oxide gene affect the forearm blood flow responses of Caucasian hypertensive patients
    • Rossi GP, Taddei S, Virdis A, Cavallin M, Ghiadoni L, et al. (2003) The T-786C and Glu298Asp polymorphisms of the endothelial nitric oxide gene affect the forearm blood flow responses of Caucasian hypertensive patients. J Am Coll Cardiol 41: 938-945.
    • (2003) J Am Coll Cardiol , vol.41 , pp. 938-945
    • Rossi, G.P.1    Taddei, S.2    Virdis, A.3    Cavallin, M.4    Ghiadoni, L.5
  • 24
    • 13944281817 scopus 로고    scopus 로고
    • Nitric oxide synthase gene G298 allele. Is it a marker for microvascular angina in hypertensive patients?
    • Nagib El-Kilany GE, Nayel E, Hazzaa S, (2004) Nitric oxide synthase gene G298 allele. Is it a marker for microvascular angina in hypertensive patients? Cardiovasc Radiat Med 5: 113-118.
    • (2004) Cardiovasc Radiat Med , vol.5 , pp. 113-118
    • Nagib El-Kilany, G.E.1    Nayel, E.2    Hazzaa, S.3
  • 25
    • 4744354403 scopus 로고    scopus 로고
    • eNOS Glu298Asp polymorphism and hypertension in a cohort study in Japanese
    • Kishimoto T, Misawa Y, Kaetu A, Nagai M, Osaki Y, et al. (2004) eNOS Glu298Asp polymorphism and hypertension in a cohort study in Japanese. Prev Med 39: 927-931.
    • (2004) Prev Med , vol.39 , pp. 927-931
    • Kishimoto, T.1    Misawa, Y.2    Kaetu, A.3    Nagai, M.4    Osaki, Y.5
  • 26
    • 17144369919 scopus 로고    scopus 로고
    • Relationship of eNOS gene variants to diseases that have in common an endothelial cell dysfunction
    • Heltianu C, Costache G, Gafencu A, Diaconu M, Bodeanu M, et al. (2005) Relationship of eNOS gene variants to diseases that have in common an endothelial cell dysfunction. J Cell Mol Med 9: 135-142.
    • (2005) J Cell Mol Med , vol.9 , pp. 135-142
    • Heltianu, C.1    Costache, G.2    Gafencu, A.3    Diaconu, M.4    Bodeanu, M.5
  • 27
    • 21644445814 scopus 로고    scopus 로고
    • Endothelial nitric oxide synthase Glu298Asp gene polymorphism, blood pressure and hypertension in a general population sample
    • Wolff B, Grabe HJ, Schlüter C, Popowski K, Völzke H, et al. (2005) Endothelial nitric oxide synthase Glu298Asp gene polymorphism, blood pressure and hypertension in a general population sample. J Hypertens 23: 1361-1366.
    • (2005) J Hypertens , vol.23 , pp. 1361-1366
    • Wolff, B.1    Grabe, H.J.2    Schlüter, C.3    Popowski, K.4    Völzke, H.5
  • 28
    • 18644367518 scopus 로고    scopus 로고
    • Ambulatory blood pressure, left ventricular mass and vascular phenotypes in relation to the endothelial nitric oxide synthase gene Glu298Asp and intron 4 polymorphisms in a population-based family study
    • Czarnecka D, Kawecka-Jaszcz K, Stolarz K, Olszanecka A, et al. (2005) Ambulatory blood pressure, left ventricular mass and vascular phenotypes in relation to the endothelial nitric oxide synthase gene Glu298Asp and intron 4 polymorphisms in a population-based family study. J Hum Hypertens 19: 413-420.
    • (2005) J Hum Hypertens , vol.19 , pp. 413-420
    • Czarnecka, D.1    Kawecka-Jaszcz, K.2    Stolarz, K.3    Olszanecka, A.4
  • 29
    • 28444460716 scopus 로고    scopus 로고
    • Endothelial NOS G894 T and MMP-3 5A/6A gene polymorphisms and hypertension in Serbian population
    • Djurić T, Zivković M, Stanković A, Mecanin S, Alavantić D, (2005) Endothelial NOS G894 T and MMP-3 5A/6A gene polymorphisms and hypertension in Serbian population. J Clin Lab Anal 19: 241-246.
    • (2005) J Clin Lab Anal , vol.19 , pp. 241-246
    • Djurić, T.1    Zivković, M.2    Stanković, A.3    Mecanin, S.4    Alavantić, D.5
  • 30
    • 14044268174 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-gamma2 Pro12Ala and endothelial nitric oxide synthase-4a/b gene polymorphisms are not associated with hypertension in diabetes mellitus type 2
    • Gouni-Berthold I, Giannakidou E, Müller-Wieland D, Faust M, Kotzka J, et al. (2005) Peroxisome proliferator-activated receptor-gamma2 Pro12Ala and endothelial nitric oxide synthase-4a/b gene polymorphisms are not associated with hypertension in diabetes mellitus type 2. J Hypertens 23: 301-308.
    • (2005) J Hypertens , vol.23 , pp. 301-308
    • Gouni-Berthold, I.1    Giannakidou, E.2    Müller-Wieland, D.3    Faust, M.4    Kotzka, J.5
  • 31
    • 17444402788 scopus 로고    scopus 로고
    • Genetic polymorphisms and endothelial dysfunction in patients with essential hypertension: a crosssectional case-control study
    • Demirel S, Akkaya V, Cine N, Oflaz H, Yekeler E, et al. (2005) Genetic polymorphisms and endothelial dysfunction in patients with essential hypertension: a crosssectional case-control study. Neth Heart J 13: 126-131.
    • (2005) Neth Heart J , vol.13 , pp. 126-131
    • Demirel, S.1    Akkaya, V.2    Cine, N.3    Oflaz, H.4    Yekeler, E.5
  • 33
    • 33746144732 scopus 로고    scopus 로고
    • Association study of the endothelial nitric oxide synthase gene polymorphisms with essential hypertension in northern Han Chinese
    • Zhao Q, Su SY, Chen SF, Li B, Gu DF, (2006) Association study of the endothelial nitric oxide synthase gene polymorphisms with essential hypertension in northern Han Chinese. Chin Med J (Engl) 119: 1065-1071.
    • (2006) Chin Med J (Engl) , vol.119 , pp. 1065-1071
    • Zhao, Q.1    Su, S.Y.2    Chen, S.F.3    Li, B.4    Gu, D.F.5
  • 34
    • 33751221022 scopus 로고    scopus 로고
    • Association analysis of endothelial nitric oxide synthase gene polymorphism with primary hypertension in a Singapore population
    • Moe KT, Lim ST, Wong P, Chua T, DeSilva DA, et al. (2006) Association analysis of endothelial nitric oxide synthase gene polymorphism with primary hypertension in a Singapore population. J Hum Hypertens 20: 956-963.
    • (2006) J Hum Hypertens , vol.20 , pp. 956-963
    • Moe, K.T.1    Lim, S.T.2    Wong, P.3    Chua, T.4    DeSilva, D.A.5
  • 35
    • 33748465709 scopus 로고    scopus 로고
    • Negative association of endothelial nitric oxide gene polymorphism with hypertension in Turkish patients: effect of ecNOS polymorphism on left ventricular hypertrophy
    • Olcay A, Ekmekci CG, Ozbek U, Sezer M, Barcin C, et al. (2006) Negative association of endothelial nitric oxide gene polymorphism with hypertension in Turkish patients: effect of ecNOS polymorphism on left ventricular hypertrophy. Cardiovasc Ultrasound 4: 33.
    • (2006) Cardiovasc Ultrasound , vol.4 , pp. 33
    • Olcay, A.1    Ekmekci, C.G.2    Ozbek, U.3    Sezer, M.4    Barcin, C.5
  • 36
    • 34249067387 scopus 로고    scopus 로고
    • Endothelial nitric oxide synthase gene intron 4, 27 bp repeat polymorphism and essential hypertension in the Kazakh Chinese population
    • Deng F, Hu Q, Tang B, He F, Guo S, et al. (2007) Endothelial nitric oxide synthase gene intron 4, 27 bp repeat polymorphism and essential hypertension in the Kazakh Chinese population. Acta Biochim Biophys Sin (Shanghai) 39: 311-316.
    • (2007) Acta Biochim Biophys Sin (Shanghai) , vol.39 , pp. 311-316
    • Deng, F.1    Hu, Q.2    Tang, B.3    He, F.4    Guo, S.5
  • 37
    • 37449017565 scopus 로고    scopus 로고
    • Association between a G894T polymorphism of eNOS gene and essential hypertension in Hani and Yi minority groups of China
    • Tang W, Yang Y, Wang B, Xiao C, (2008) Association between a G894T polymorphism of eNOS gene and essential hypertension in Hani and Yi minority groups of China. Arch Med Res 39: 222-225.
    • (2008) Arch Med Res , vol.39 , pp. 222-225
    • Tang, W.1    Yang, Y.2    Wang, B.3    Xiao, C.4
  • 38
    • 47649113638 scopus 로고    scopus 로고
    • Gender specific association of endothelial nitric oxide synthase gene (Glu298Asp) polymorphism with essential hypertension in a south Indian population
    • Periaswamy R, Gurusamy U, Shewade DG, Cherian A, Swaminathan RP, et al. (2008) Gender specific association of endothelial nitric oxide synthase gene (Glu298Asp) polymorphism with essential hypertension in a south Indian population. Clin Chim Acta 395: 134-136.
    • (2008) Clin Chim Acta , vol.395 , pp. 134-136
    • Periaswamy, R.1    Gurusamy, U.2    Shewade, D.G.3    Cherian, A.4    Swaminathan, R.P.5
  • 39
    • 37249012924 scopus 로고    scopus 로고
    • Candidate gene polymorphisms and their association with hypertension in Malays
    • Ghazali DM, Rehman A, Rahman AR, (2008) Candidate gene polymorphisms and their association with hypertension in Malays. Clin Chim Acta 388: 46-50.
    • (2008) Clin Chim Acta , vol.388 , pp. 46-50
    • Ghazali, D.M.1    Rehman, A.2    Rahman, A.R.3
  • 40
    • 35748964459 scopus 로고    scopus 로고
    • Association of eNOS Glu298Asp gene polymorphism with essential hypertension in Asian Indians
    • Srivastava K, Narang R, Sreenivas V, Das S, Das N, (2008) Association of eNOS Glu298Asp gene polymorphism with essential hypertension in Asian Indians. Clin Chim Acta 387: 80-83.
    • (2008) Clin Chim Acta , vol.387 , pp. 80-83
    • Srivastava, K.1    Narang, R.2    Sreenivas, V.3    Das, S.4    Das, N.5
  • 41
    • 74249115384 scopus 로고    scopus 로고
    • 4G/5G variant of plasminogen activator inhibitor-1 gene and severe pregnancy-induced hypertension: subgroup analyses of variants of angiotensinogen and endothelial nitric oxide synthase
    • Kobashi G, Ohta K, Yamada H, Hata A, Minakami H, et al. (2009) 4G/5G variant of plasminogen activator inhibitor-1 gene and severe pregnancy-induced hypertension: subgroup analyses of variants of angiotensinogen and endothelial nitric oxide synthase. J Epidemiol 19: 275-280.
    • (2009) J Epidemiol , vol.19 , pp. 275-280
    • Kobashi, G.1    Ohta, K.2    Yamada, H.3    Hata, A.4    Minakami, H.5
  • 42
    • 58549089281 scopus 로고    scopus 로고
    • Endothelial nitric oxide synthase genetic variation and essential hypertension risk in Han Chinese: the Fangshan study
    • Niu WQ, Qi Y, Zhang LT, Qi YX, Wang B, et al. (2009) Endothelial nitric oxide synthase genetic variation and essential hypertension risk in Han Chinese: the Fangshan study. J Hum Hypertens 23: 136-139.
    • (2009) J Hum Hypertens , vol.23 , pp. 136-139
    • Niu, W.Q.1    Qi, Y.2    Zhang, L.T.3    Qi, Y.X.4    Wang, B.5
  • 43
    • 67349139914 scopus 로고    scopus 로고
    • Association of a 27-bp repeat polymorphism in intron 4 of endothelial constitutive nitric oxide synthase gene with hypertension in a Tunisian population
    • Jemaa R, Ben Ali S, Kallel A, Feki M, Elasmi M, et al. (2009) Association of a 27-bp repeat polymorphism in intron 4 of endothelial constitutive nitric oxide synthase gene with hypertension in a Tunisian population. Clin Biochem 42: 852-856.
    • (2009) Clin Biochem , vol.42 , pp. 852-856
    • Jemaa, R.1    Ben Ali, S.2    Kallel, A.3    Feki, M.4    Elasmi, M.5
  • 44
    • 70249125473 scopus 로고    scopus 로고
    • High risk of essential hypertension in males with intron 4 VNTR polymorphism of eNOS gene
    • Patkar S, Charita BH, Ramesh C, Padma T, (2009) High risk of essential hypertension in males with intron 4 VNTR polymorphism of eNOS gene. Indian J Hum Genet 15: 49-53.
    • (2009) Indian J Hum Genet , vol.15 , pp. 49-53
    • Patkar, S.1    Charita, B.H.2    Ramesh, C.3    Padma, T.4
  • 45
    • 77951234165 scopus 로고    scopus 로고
    • Endothelial nitric oxide synthase haplotypes associated with hypertension do not predispose to cardiac hypertrophy
    • Vasconcellos V, Lacchini R, Jacob-Ferreira AL, Sales ML, Ferreira-Sae MC, et al. (2010) Endothelial nitric oxide synthase haplotypes associated with hypertension do not predispose to cardiac hypertrophy. DNA Cell Biol 29: 171-176.
    • (2010) DNA Cell Biol , vol.29 , pp. 171-176
    • Vasconcellos, V.1    Lacchini, R.2    Jacob-Ferreira, A.L.3    Sales, M.L.4    Ferreira-Sae, M.C.5
  • 46
    • 76349118976 scopus 로고    scopus 로고
    • Association of NOS3 Glu298Asp SNP with hypertension and possible effect modification of dietary fat intake in the ARIC study
    • Kingah PL, Luu HN, Volcik KA, Morrison AC, Nettleton JA, Boerwinkle E, (2010) Association of NOS3 Glu298Asp SNP with hypertension and possible effect modification of dietary fat intake in the ARIC study. Hypertens Res 33: 165-169.
    • (2010) Hypertens Res , vol.33 , pp. 165-169
    • Kingah, P.L.1    Luu, H.N.2    Volcik, K.A.3    Morrison, A.C.4    Nettleton, J.A.5    Boerwinkle, E.6
  • 47
    • 79957516138 scopus 로고    scopus 로고
    • An NOS3 Haplotype is Protective against Hypertension in a Caucasian Population
    • Kitsios GD, Zintzaras E, (2010) An NOS3 Haplotype is Protective against Hypertension in a Caucasian Population. Int J Hypertens 2010: 865031.
    • (2010) Int J Hypertens , vol.2010 , pp. 865031
    • Kitsios, G.D.1    Zintzaras, E.2
  • 48
    • 77953609429 scopus 로고    scopus 로고
    • Lack of association between endothelial nitric oxide synthase gene G894T polymorphism hypertension in the Tunisian population
    • Sediri Y, Kallel A, Ayadi I, Feki M, Elasmi M, et al. (2010) Lack of association between endothelial nitric oxide synthase gene G894T polymorphism hypertension in the Tunisian population. Prev Med 51: 88-89.
    • (2010) Prev Med , vol.51 , pp. 88-89
    • Sediri, Y.1    Kallel, A.2    Ayadi, I.3    Feki, M.4    Elasmi, M.5
  • 49
    • 33750586809 scopus 로고    scopus 로고
    • Endothelial NO synthase gene polymorphisms and hypertension: a meta-analysis
    • Zintzaras E, Kitsios G, Stefanidis I, (2006) Endothelial NO synthase gene polymorphisms and hypertension: a meta-analysis. Hypertension 48: 700-710.
    • (2006) Hypertension , vol.48 , pp. 700-710
    • Zintzaras, E.1    Kitsios, G.2    Stefanidis, I.3
  • 50
    • 34548385729 scopus 로고    scopus 로고
    • Three endothelial nitric oxide (NOS3) gene polymorphisms in hypertensive and normotensive individuals: meta-analysis of 53 studies reveals evidence of publication bias
    • Pereira TV, Rudnicki M, Cheung BM, Baum L, Yamada Y, et al. (2007) Three endothelial nitric oxide (NOS3) gene polymorphisms in hypertensive and normotensive individuals: meta-analysis of 53 studies reveals evidence of publication bias. J Hypertens 25: 1763-1774.
    • (2007) J Hypertens , vol.25 , pp. 1763-1774
    • Pereira, T.V.1    Rudnicki, M.2    Cheung, B.M.3    Baum, L.4    Yamada, Y.5
  • 51
    • 67649780090 scopus 로고    scopus 로고
    • Haplotype-based association of the renin-angiotensin-aldosterone system genes polymorphisms with essential hypertension among Han Chinese: the Fangshan study
    • Niu W, Qi Y, Hou S, Zhai X, Zhou W, Qiu C, (2009) Haplotype-based association of the renin-angiotensin-aldosterone system genes polymorphisms with essential hypertension among Han Chinese: the Fangshan study. J Hypertens 27: 1384-1391.
    • (2009) J Hypertens , vol.27 , pp. 1384-1391
    • Niu, W.1    Qi, Y.2    Hou, S.3    Zhai, X.4    Zhou, W.5    Qiu, C.6
  • 53
    • 0031459896 scopus 로고    scopus 로고
    • Genetic contribution of the endothelial constitutive nitric oxide synthase gene to plasma nitric oxide levels
    • Wang XL, Mahaney MC, Sim AS, Wang J, Wang J, et al. (1997) Genetic contribution of the endothelial constitutive nitric oxide synthase gene to plasma nitric oxide levels. Arterioscler Thromb Vasc Biol 17: 3147-3153.
    • (1997) Arterioscler Thromb Vasc Biol , vol.17 , pp. 3147-3153
    • Wang, X.L.1    Mahaney, M.C.2    Sim, A.S.3    Wang, J.4    Wang, J.5
  • 54
    • 4143145303 scopus 로고    scopus 로고
    • Meta-analysis of genetic association studies
    • Munafò MR, Flint J, (2004) Meta-analysis of genetic association studies. Trends Genet 20: 439-444.
    • (2004) Trends Genet , vol.20 , pp. 439-444
    • Munafò, M.R.1    Flint, J.2
  • 55
    • 77957680429 scopus 로고    scopus 로고
    • Methods in epidemiology: observational study designs
    • DiPietro NA, (2010) Methods in epidemiology: observational study designs. Pharmacotherapy 30: 973-984.
    • (2010) Pharmacotherapy , vol.30 , pp. 973-984
    • DiPietro, N.A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.