Chagasic thymic atrophy does not affect negative selection but results in the export of activated CD4+CD8+ T cells in severe forms of human disease

PLoS Neglected Tropical Diseases

Volumn 5, Issue 8, 2011, Pages

  Morrot, Alexandre ^a,b   Terra Granado, Eugênia ^b   Pérez, Ana Rosa ^c   Silva Barbosa, Suse Dayse ^b,d   Milićević, Novica M ^e   Farias de Oliveira, Désio Aurélio ^b   Berbert, Luiz Ricardo ^b   de Meis, Juliana ^b   Takiya, Christina Maeda ^a   Beloscar, Juan ^c   Wang, Xiaoping ^f   Kont, Vivian ^f   Peterson, Pärt ^f   Bottasso, Oscar ^c   Savino, Wilson ^b  

^a FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^b INSTITUTO OSWALDO CRUZ   (Brazil)

^c FACULTAD DE CIENCIAS MÉDICAS   (Argentina)

^d INSTITUTO NACIONAL DE CÂNCER   (Brazil)

^e UNIVERSITY OF BELGRADE   (Serbia)

^f UNIVERSITY OF TARTU   (Estonia)

Author keywords

[No Author keywords available]

Indexed keywords

BIM PROTEIN; OVALBUMIN; T LYMPHOCYTE RECEPTOR; CD4 ANTIGEN; CD8 ANTIGEN;

ADULT; AIRE GENE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CHAGAS DISEASE; CLINICAL ARTICLE; CONGESTIVE CARDIOMYOPATHY; CONTROLLED STUDY; DISEASE SEVERITY; GENE; GENE EXPRESSION; HUMAN; LYMPHOCYTE ACTIVATION; MACROPHAGE; MALE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; THYMOCYTE; THYMUS ATROPHY; TRA GENE; ANIMAL; ATROPHY; BAGG ALBINO MOUSE; CHEMISTRY; FEMALE; GENE EXPRESSION PROFILING; IMMUNOLOGY; MIDDLE AGED; PATHOGENICITY; PATHOLOGY; T LYMPHOCYTE SUBPOPULATION; THYMUS; TRYPANOSOMA CRUZI;

ADULT; ANIMALS; ANTIGENS, CD4; ANTIGENS, CD8; ATROPHY; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CHAGAS DISEASE; FEMALE; GENE EXPRESSION PROFILING; HUMANS; LYMPHOCYTE ACTIVATION; MALE; MICE; MICE, INBRED BALB C; MIDDLE AGED; T-LYMPHOCYTE SUBSETS; THYMUS GLAND; TRYPANOSOMA CRUZI;

EID: 80052422547     PISSN: 19352727     EISSN: 19352735     Source Type: Journal    
DOI: 10.1371/journal.pntd.0001268     Document Type: Article

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