Direct effects of HIV-1 tat on excitability and survival of primary dorsal root ganglion neurons: Possible contribution to HIV-1-associated pain

PLoS ONE

Volumn 6, Issue 9, 2011, Pages

  Chi, Xianxun ^a   Amet, Tohti ^a   Byrd, Daniel ^a   Chang, Kuei Hua ^b   Shah, Kavita ^b   Hu, Ningjie ^a   Grantham, Ayslinn ^a   Hu, Sishun ^a   Duan, Jianhong ^a   Tao, Feng ^c   Nicol, Grant ^a   Yu, Qigui ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b PURDUE UNIVERSITY   (United States)

^c JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CAPSAICIN; CYCLIN DEPENDENT KINASE 5; GAG PROTEIN; MESSENGER RNA; ROSCOVITINE; TRANSACTIVATOR PROTEIN; PROTEIN KINASE INHIBITOR;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL SURVIVAL; CONTROLLED STUDY; DISEASE ASSOCIATION; DOWN REGULATION; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; MALE; MEMBRANE STEADY POTENTIAL; NERVE CELL EXCITABILITY; NERVE POTENTIAL; NEUROPATHIC PAIN; NONHUMAN; PROTEIN FUNCTION; RAT; SENSORY NERVE CELL; SIGNAL TRANSDUCTION; SPINAL GANGLION; ACTION POTENTIAL; ANIMAL; BIOSYNTHESIS; CELL SIZE; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; GENETICS; HUMAN IMMUNODEFICIENCY VIRUS 1; METABOLISM; NERVE CELL; PAIN; PATHOLOGY; SPRAGUE DAWLEY RAT; TIME; VIROLOGY;

HUMAN IMMUNODEFICIENCY VIRUS 1; RATTUS;

ACTION POTENTIALS; ANIMALS; APOPTOSIS; CAPSAICIN; CELL SIZE; CELL SURVIVAL; CYCLIN-DEPENDENT KINASE 5; GANGLIA, SPINAL; HIV-1; MALE; NEURONS; PAIN; PROTEIN KINASE INHIBITORS; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; TAT GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS; TIME FACTORS;

EID: 80052420493     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0024412     Document Type: Article

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