Manipulation of the potassium channel Kv1.1 and its effect on neuronal excitability in rat sensory neurons

Journal of Neurophysiology

Volumn 98, Issue 5, 2007, Pages 2683-2692

  Xian, Xuan Chi ^a   Nicol, G D ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CAPSAICIN; DENDROTOXIN K; POTASSIUM CHANNEL BLOCKING AGENT; POTASSIUM CHANNEL KV1.1; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ACTION POTENTIAL; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; MALE; NERVE CELL EXCITABILITY; NERVE CELL MEMBRANE STEADY POTENTIAL; NONHUMAN; POTASSIUM CURRENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; RNA INTERFERENCE; SENSORY NERVE CELL; WESTERN BLOTTING;

ANIMALS; DOSE-RESPONSE RELATIONSHIP, RADIATION; DRUG INTERACTIONS; ELECTRIC STIMULATION; GANGLIA, SPINAL; GENE EXPRESSION; KV1.1 POTASSIUM CHANNEL; MALE; MEMBRANE POTENTIALS; NEURONS, AFFERENT; PATCH-CLAMP TECHNIQUES; PEPTIDES; RATS; RATS, SPRAGUE-DAWLEY; RNA, SMALL INTERFERING;

EID: 36248948549     PISSN: 00223077     EISSN: 15221598     Source Type: Journal    
DOI: 10.1152/jn.00437.2007     Document Type: Article

References (59)

1. Baumann A, Grupe A, Ackermann A, Pongs O. Structure of the voltage-dependent potassium channel is highly conserved from Drosophila to vertebrate central nervous systems. EMBO J 7: 2457-2463, 1988.
2. Beekwilder JP, O'Leary ME, van den Broek LP, van Kempen GT, Ypey DL, van den Berg RJ. Kv1.1 channels of dorsal root ganglion neurons are inhibited by n-butyl-p-aminobenzoate, a promising anesthetic for the treatment of chronic pain. J Pharmacol Exp Ther 304: 531-538, 2003.
3. Bosma MM, Allen ML, Martin TM, Tempel BL. PKA-dependent regulation of mKv1.1, a mouse Shaker-like potassium channel gene, when stably expressed in CHO cells. J Neurosci 13: 5242-5250, 1993.
4. + conductances with complementary functions in postsynaptic integration at a central auditory synapse. J Neurosci 15: 8011-8022, 1995.
5. Brew HM, Hallows JL, Tempel BL. Hyperexcitability and reduced low threshold potassium currents in auditory neurons of mice lacking the channel subunit Kv1.1. J Physiol 548: 1-20, 2003.
6. Chandry KG, Gutman GA. Voltage-gated potassium channel genes. In: Handbook of Receptors and Channels, edited by North RA. Boca Raton, FL: CRC Press, 1995, p. 1-17.
7. Christie MJ, North RA, Osborne PB, Douglass J, Adelman JP. Heteropolymeric potassium channels expressed in Xenopus oocytes from cloned subunits. Neuron 4: 405-411, 1990.
8. + channels. Ann NY Acad Sci 868: 233-285, 1999.
9. Cotella D, Jost N, Darna M, Radicke S, Ravens U, Wettwer E. Silencing the cardiac potassium channel Kv4.3 by RNA interference in a CHO expression system. Biochem Biophys Res Commun 330: 555-560, 2005.
10. Dodson PD, Barker MC, Forsythe ID. Two heteromeric Kv1 potassium channels differentially regulate action potential firing. J Neurosci 22: 6953-6961, 2002.
11. Glazebrook PA, Ramirez AN, Schild JH, Shieh CC, Doan T, Wible BA, Kunze DL. Potassium channels Kv1.1, Kv1.2 and Kv1.6 influence excitability of rat visceral sensory neurons. J Physiol 541: 467-482, 2002.
12. Gonczi M, Szentandrassy N, Johnson IT, Heagerty AM, Weston AH. Investigation of the role of TASK-2 channels in rat pulmonary arteries; pharmacological and functional studies following RNA interference procedures. Br J Pharmacol 147: 496-505, 2006.
13. + channels, types Kv1.1, 1.2, 1.3, 1.5, and 3.1, stably expressed in mammalian cell lines. Mol Pharmacol 45: 1227-1234, 1994.
14. Grupe A, Schroter KH, Ruppersberg JP, Stocker M, Drewes T, Beckh S, Pongs O. Cloning and expression of a human voltage-gated potassium channel. A novel member of the RCK potassium channel family. EMBO J 9: 1749-1756, 1990.
15. + currents in rat primary sensory neurones. Mol Pain 2: 12-24, 2006.
16. Gurney AM, Hunter E. The use of small interfering RNA to elucidate the activity and function of ion channel genes in an intact tissue. J Pharmacol Toxicol Methods 51: 253-262, 2005.
17. Gutman GA, Chandy KG, Adelman JP, Aiyar J, Bayliss DA, Clapham DE, Covarriubias M, Desir GV, Furuichi K, Ganetzky B, Garcia ML, Grissmer S, Jan LY, Karschin A, Kim D, Kuperschmidt S, Kurachi Y, Lazdunski M, Lesage F, Lester HA, McKinnon D, Nichols CG, O'Kelly I, Robbins J, Robertson GA, Rudy B, Sanguinetti M, Seino S, Stuehmer W, Tamkun MM, Vandenberg CA, Wei A, Wulff H, Wymore RS. International Union of Pharmacology. XLI. Compendium of voltage-gated ion channels: potassium channels. Pharmacol Rev 55: 583-586, 2003.
18. Gutman GA, Chandy KG, Grissmer S, Lazdunski M, McKinnon D, Pardo LA, Robertson GA, Rudy B, Sanguinetti MC, Stuhmer W, Wang X. International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels. Pharmacol Rev 57: 473-508, 2005.
19. Hamill OP, Marty A, Neher E, Sakmann B, Sigworth FJ. Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches. Pfluegers Arch 391: 85-100, 1981.
20. Harper AA, Lawson SN. Conduction velocity is related to morphological cell type in rat dorsal root ganglion neurones. J Physiol 359: 31-46, 1985.
21. Harvey AL, Karlsson E. Dendrotoxin from the venom of the green mamba, Dendroaspis angusticeps. A neurotoxin that enhances acetylcholine release at neuromuscular junction. Naunyn Schmiedebergs Arch Pharmacol 312: 1-6, 1980.
22. Holzer P. Capsaicin: cellular targets, mechanisms of action, and selectivity for thin sensory neurons. Pharmacol Rev 43: 143-201, 1991.
23. Hopkins WF. Toxin and subunit specificity of blocking affinity of three peptide toxins for heteromultimeric, voltage-gated potassium channels expressed in Xenopus oocytes. J Pharmacol Exp Ther 285: 1051-1060, 1998.
24. Isacoff EY, Jan YN, Jan LY. Evidence for the formation of heteromultimeric potassium channels in Xenopus oocytes. Nature 345: 530-534, 1990.
25. Ishikawa K, Tanaka M, Black JA, Waxman SG. Changes in expression of voltage-gated potassium channels in dorsal root ganglion neurons following axotomy. Muscle Nerve 22: 502-507, 1999.
26. Kim DS, Choi JO, Rim HD, Cho HJ. Downregulation of voltage-gated potassium channel alpha gene expression in dorsal root ganglia following chronic constriction injury of the rat sciatic nerve. Brain Res Mol Brain Res 105: 146-152, 2002.
27. Koerber HR, Druzinsky RE, Mendell LM. Properties of somata of spinal dorsal root ganglion cells differ according to peripheral receptor innervated. J Neurophysiol 60: 1584-1596, 1988.
28. Lindsay RM. Nerve growth factors (NGF, BDNF) enhance axonal regeneration but are not required for survival of adult sensory neurons. J Neurosci 8: 2394-2405, 1988.
29. Lopantsev V, Tempel BL, Schwartzkroin PA. Hyperexcitability of CA3 pyramidal cells in mice lacking the potassium channel subunit Kv1.1. Epilepsia 44: 1506-1512, 2003.
30. Manganas LN, Trimmer JS. Subunit composition determines Kv1 potassium channel surface expression. J Biol Chem 275: 29685-29693, 2000.
31. + channel, mKv1.1 (MK-1), when stably expressed in Chinese hamster ovary cells. Br J Pharmacol 120: 1029-1034, 1997.
32. Penner R, Petersen M, Pierau FK, Dreyer F. Dendrotoxin: a selective blocker of a non-inactivating potassium current in guinea-pig dorsal root ganglion neurones. Pfluegers Arch 407: 365-369, 1986.
33. Petruska JC, Napaporn J, Johnson RD, Gu JG, Cooper BY. Subclassified acutely dissociated cells of rat DRG: histochemistry and patterns of capsaicin-, proton-, and ATP-activated currents. J Neurophysiol 84: 2365-2379, 2000.
34. Pongs O. Molecular biology of voltage-dependent potassium channels. Physiol Rev 72: S69-S88, 1992.
35. Rasband MN, Park EW, Vanderah TW, Lai J, Porreca F, Trimmer JS. Distinct potassium channels on pain-sensing neurons. Proc Natl Acad Sci USA 98: 13373-13378, 2001.
36. Rho JM, Szot P, Tempel BL, Schwartzkroin PA. Developmental seizure susceptibility of Kv1.1 potassium channel knockout mice. Dev Neurosci 21: 320-327, 1999.
37. Ritter AM, Mendell LM. Somal membrane properties of physiologically identified sensory neurons in the rat: effects of nerve growth factor. J Neurophysiol 68: 2033-2041, 1992.
38. Robertson B, Owen DG. Pharmacology of a cloned potassium channel from mouse brain (MK-1) expressed in CHO cells: effects of blockers and an "inactivation peptide." Br J Pharmacol 109: 725-735, 1993.
39. Robertson B, Owen D, Stow J, Butler C, Newland C. Novel effects of dendrotoxin homologues on subtypes of mammalian Kv1 potassium channels expressed in Xenopus oocytes. FEBS Lett 383: 26-30, 1996.
40. Ruppersberg JP, Schroter KH, Sakmann B, Stocker M, Sewing S, Pongs O. Heteromultimeric channels formed by rat brain potassium-channel proteins. Nature 345: 535-537, 1990.
41. Schwarz TL, Tempel BL, Papazian DM, Jan YN, Jan LY. Multiple potassium-channel components are produced by alternative splicing at the Shaker locus in Drosophila. Nature 331: 137-142, 1988.
42. + channels in bovine brain. Biochemistry 33: 1617-1623, 1994.
43. + channel Kv1 subtypes in synaptic membranes from bovine brain. Biochemistry 36: 8195-8201, 1997.
44. Smart SL, Lopantsev V, Zhang CL, Robbins CA, Wang H, Chiu SY, Schwartzkroin PA, Messing A, Tempel BL. Deletion of the K(V)1.1 potassium channel causes epilepsy in mice. Neuron 20: 809-819, 1998.
45. Song WJ, Tkatch T, Baranauskas G, Ichinohe N, Kitai ST, Surmeier DJ. Somatodendritic depolarization-activated potassium currents in rat neostriatal cholinergic interneurons are predominantly of the A type and attributable to coexpression of Kv4.2 and Kv4.1 subunits. J Neurosci 18: 3124-3137, 1998.
46. + channels in dorsal root ganglion cells. Neurosci Lett 93: 49-55, 1988.
47. Stansfeld CE, Marsh SJ, Halliwell JV, Brown DA. 4-Aminopyridine and dendrotoxin induce repetitive firing in rat visceral sensory neurones by blocking a slowly inactivating outward current. Neurosci Lett 64: 299-304, 1986.
48. Stansfeld CE, Marsh SJ, Parcej DN, Dolly JO, Brown DA. Mast cell degranulating peptide and dendrotoxin selectively inhibit a fast-activating potassium current and bind to common neuronal proteins. Neuroscience 23: 893-902, 1987.
49. Stuhmer W, Stocker M, Sakmann B, Seeburg P, Baumann A, Grupe A, Pongs O. Potassium channels expressed from rat brain cDNA have delayed rectifier properties. FEBS Lett 242: 199-206, 1988.
50. Tempel BL, Jan YN, Jan LY. Cloning of a probable potassium channel gene from mouse brain. Nature 332: 837-839, 1988.
51. Tempel BL, Papazian DM, Schwarz TL, Jan YN, Jan LY. Sequence of a probable potassium channel component encoded at Shaker locus of Drosophila. Science 237: 770-775, 1987.
52. Vasko MR, Guo C, Kelley MR. The multifunctional DNA repair/redox enzyme Ape1/Ref-1 promotes survival of neurons after oxidative stress. DNA Repair (Amst) 4: 367-379, 2005.
53. + channel subtypes fractionated from rat brain using dendrotoxins. Eur J Biochem 263: 230-237, 1999.
54. + channels in terminal and juxtaparanodal regions of neurons. Nature 365: 75-79, 1993.
55. Wang H, Kunkel DD, Schwartzkroin PA, Tempel BL. Localization of Kv1.1 and Kv1.2, two K channel proteins, to synaptic terminals, somata, and dendrites in the mouse brain. J Neurosci 14: 4588-4599, 1994.
56. Yang EK, Takimoto K, Hayashi Y, de Groat WC, Yoshimura N. Altered expression of potassium channel subunit mRNA and alpha-dendrotoxin sensitivity of potassium currents in rat dorsal root ganglion neurons after axotomy. Neuroscience 123: 867-874, 2004.
57. + currents and action potentials in tetrodotoxin-resistant adult rat trigeminal ganglion neurons. J Pharmacol Exp Ther 314: 437-445, 2005.
58. + current in rat sensory neurons. J Physiol 544: 385-402, 2002.
59. Zhang YH, Vasko MR, Nicol GD. Intracellular sphingosine 1-phosphate mediates the increased excitability produced by nerve growth factor in rat sensory neurons. J Physiol 575: 101-113, 2006.