Nuclear Factor-κB (NF-κB) mediates a protective response in cancer cells treated with inhibitors of fatty acid synthase

Journal of Biological Chemistry

Volumn 286, Issue 36, 2011, Pages 31457-31465

  Lemmon, Colleen R M ^a,b   Woo, Ju Hyung ^a   Tully, Ellen ^a   Wilsbach, Kathleen ^a   Gabrielson, Edward ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b GLAXOSMITHKLINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTIVE RESPONSE; BORTEZOMIB; CANCER CELLS; CELL KILLING; CELLULAR STRESS; FATTY ACID BIOSYNTHESIS; FATTY ACID SYNTHASE; IMMUNOFLUORESCENCE MICROSCOPY; ISOFORMS; LUNG CANCER CELLS; METABOLIC STRESS; NEOPLASTIC CELLS; NUCLEAR FACTORS; PHARMACOLOGICAL INHIBITORS; PROTEIN KINASE C;

ACTIVATION ANALYSIS; BIOCHEMISTRY; BIOELECTRIC POTENTIALS; DISEASES; ENZYME INHIBITION; FATTY ACIDS; METABOLISM; PHOSPHORYLATION;

CELLS;

2 [1 (3 AMIDINOTHIOPROPYL) 1H INDOL 3 YL] 3 (1 METHYL 1H INDOL 3 YL)MALEIMIDE; BORTEZOMIB; C 93; CYCLOOXYGENASE 2; FATTY ACID SYNTHASE; FATTY ACID SYNTHASE INHIBITOR; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; INTERLEUKIN 8; LUCIFERASE; PROTEIN KINASE C ALPHA; PROTEIN KINASE C BETA; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR RELA; UNCLASSIFIED DRUG; ENZYME INHIBITOR; PROTECTIVE AGENT; PROTEIN KINASE C;

ARTICLE; CANCER CELL; CELL KILLING; CELL NUCLEUS; CELL PROTECTION; CELL STRESS; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; FATTY ACID SYNTHESIS; GENE EXPRESSION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; LUNG CANCER; METABOLIC STRESS; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; DRUG ANTAGONISM; LUNG TUMOR; METABOLISM; NEOPLASM; PATHOLOGY; PHOSPHORYLATION; PHYSIOLOGY; TUMOR CELL LINE;

CELL LINE, TUMOR; ENZYME INHIBITORS; FATTY ACID SYNTHETASE COMPLEX; HUMANS; LUNG NEOPLASMS; NEOPLASMS; NF-KAPPA B; PHOSPHORYLATION; PROTECTIVE AGENTS; PROTEIN KINASE C;

EID: 80052394827     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.274308     Document Type: Article

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