Protection by pyruvate against glutamate neurotoxicity is mediated by astrocytes through a glutathione-dependent mechanism

Molecular Biology Reports

Volumn 38, Issue 5, 2011, Pages 3235-3242

  Miao, Yifeng ^a,b   Qiu, Yongming ^b   Lin, Yuchang ^a   Miao, Zengli ^a   Zhang, Jing ^a   Lu, Xiaojie ^a  

^a NANJING MEDICAL UNIVERSITY   (China)

^b SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Astrocytes; Glutamate toxicity; Glutathione; Neuroprotection; Pyruvate

Indexed keywords

GLUTAMIC ACID; GLUTATHIONE; PYRUVIC ACID;

ANIMAL CELL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; ASTROCYTE; BRAIN CORTEX; CELL POPULATION; COCULTURE; CONTROLLED STUDY; EMBRYO; EXCITOTOXICITY; FEMALE; MACROGLIA; NERVE CELL CULTURE; NEUROPROTECTION; NONHUMAN; PROTEIN FUNCTION; PROTEIN SYNTHESIS REGULATION; RAT; UPREGULATION;

ANIMALS; ASTROCYTES; CELLS, CULTURED; COCULTURE TECHNIQUES; GLUTAMIC ACID; GLUTATHIONE; NEURONS; NEUROPROTECTIVE AGENTS; PYRUVIC ACID; RATS; RATS, LONG-EVANS;

RATTUS;

EID: 80052381531     PISSN: 03014851     EISSN: 15734978     Source Type: Journal    
DOI: 10.1007/s11033-010-9998-0     Document Type: Article

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