A method for efficient calculation of diffusion and reactions of lipophilic compounds in complex cell geometry

PLoS ONE

Volumn 6, Issue 8, 2011, Pages

  Dreij, Kristian ^a   Chaudhry, Qasim Ali ^b   Jernström, Bengt ^a   Morgenstern, Ralf ^a   Hanke, Michael ^b  

^a KAROLINSKA INSTITUTE   (Sweden)

^b ROYAL INSTITUTE OF TECHNOLOGY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

CARCINOGEN; POLYCYCLIC AROMATIC HYDROCARBON; BENZO[A]PYRENE 7,8 DIHYDRODIOL 9,10 OXIDE;

ARTICLE; CELL CULTURE; CELL FUNCTION; CELL METABOLISM; CELL STRAIN V 79; CELL STRUCTURE; CHEMICAL REACTION; COMPARTMENT MODEL; COMPUTER MODEL; DIFFUSION; GEOMETRY; HYDROPHOBICITY; MATHEMATICAL ANALYSIS; MATHEMATICAL MODEL; PHYSICAL CHEMISTRY; SOLVOLYSIS; ANIMAL; BIOLOGICAL MODEL; CELL LINE; CELL MEMBRANE; CHEMICAL PHENOMENA; CHEMISTRY; DNA ADDUCT; DRUG EFFECT; HUMAN; INTRACELLULAR SPACE; METABOLISM; METHODOLOGY; TOXICITY TESTING; TRANSPORT AT THE CELLULAR LEVEL;

MAMMALIA;

7,8-DIHYDRO-7,8-DIHYDROXYBENZO(A)PYRENE 9,10-OXIDE; ANIMALS; BIOLOGICAL TRANSPORT; CARCINOGENS, ENVIRONMENTAL; CELL LINE; CELL MEMBRANE; DIFFUSION; DNA ADDUCTS; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; INTRACELLULAR SPACE; MODELS, BIOLOGICAL; TOXICITY TESTS;

EID: 80052334702     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0023128     Document Type: Article

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