Ca2+-induced delayed afterdepolarizations are triggered by dyadic subspace Ca2+ affirming that increasing SERCA reduces aftercontractions

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 301, Issue 3, 2011, Pages

  Fink, Martin ^a   Noble, Penelope J ^a   Noble, Denis ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Mathematical model; Ryanodine receptor; Sarco(endo)plasmic reticulum 2+ ATPase; Sarcoplasmic reticulum

Indexed keywords

CALCIUM; RYANODINE RECEPTOR; SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE; SODIUM CALCIUM EXCHANGE PROTEIN;

ANIMAL CELL; ARTICLE; CALCIUM INDUCED DELAYED AFTERDEPOLARIZATION; CALCIUM SIGNALING; CALCIUM TRANSPORT; CELL LEVEL; CYTOSOL; ENDOPLASMIC RETICULUM; HEART DEPOLARIZATION; HEART FAILURE; HEART MUSCLE CONTRACTILITY; HUMAN; HUMAN CELL; MATHEMATICAL MODEL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SARCOPLASMIC RETICULUM; ACTION POTENTIAL; ANIMAL; BIOLOGICAL MODEL; COMPUTER SIMULATION; DIFFUSION; ENZYMOLOGY; EXCITATION CONTRACTION COUPLING; HEART CONTRACTION; HEART MUSCLE; KINETICS; METABOLISM; OSCILLOMETRY; PATHOPHYSIOLOGY;

ACTION POTENTIALS; ANIMALS; CALCIUM; COMPUTER SIMULATION; DIFFUSION; EXCITATION CONTRACTION COUPLING; HEART FAILURE; HUMANS; KINETICS; MODELS, CARDIOVASCULAR; MYOCARDIAL CONTRACTION; MYOCARDIUM; OSCILLOMETRY; RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL; SARCOPLASMIC RETICULUM; SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES; SODIUM-CALCIUM EXCHANGER;

EID: 80052324838     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.01055.2010     Document Type: Article

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