-
1
-
-
38049115875
-
Apoptosis and autophagy: regulatory connections between two supposedly different processes
-
Andrew T. Apoptosis and autophagy: regulatory connections between two supposedly different processes. Apoptosis 2008, 13:1-9.
-
(2008)
Apoptosis
, vol.13
, pp. 1-9
-
-
Andrew, T.1
-
2
-
-
33845501864
-
Apoptosome: a platform for the activation of initiator caspases
-
Bao Q., Shi Y. Apoptosome: a platform for the activation of initiator caspases. Cell Death Differ. 2007, 14:56-65.
-
(2007)
Cell Death Differ.
, vol.14
, pp. 56-65
-
-
Bao, Q.1
Shi, Y.2
-
3
-
-
0033790715
-
TRAIL receptor-2 signals apoptosis through FADD and caspase-8
-
Bodmer J.L., Holler N., Reynard S., Vinciguerra P., Schneider P., Juo P., Blenis J., Tschopp J. TRAIL receptor-2 signals apoptosis through FADD and caspase-8. Nat. Cell Biol. 2000, 2:241-243.
-
(2000)
Nat. Cell Biol.
, vol.2
, pp. 241-243
-
-
Bodmer, J.L.1
Holler, N.2
Reynard, S.3
Vinciguerra, P.4
Schneider, P.5
Juo, P.6
Blenis, J.7
Tschopp, J.8
-
4
-
-
0037213368
-
The Bcl-2 protein family: sensors and checkpoints for life-or-death decisions
-
Borner C. The Bcl-2 protein family: sensors and checkpoints for life-or-death decisions. Mol. Immunol. 2003, 39:615-647.
-
(2003)
Mol. Immunol.
, vol.39
, pp. 615-647
-
-
Borner, C.1
-
5
-
-
0034068587
-
Opposite effects of antimicrotubule agents on c-myc oncogene expression depending on the cell lines used
-
Bourgarel-Rey V., El Khyari S., Rimet O., Bordas B., Guigal N., Braguer D., Seree E., Barra Y., Briand C. Opposite effects of antimicrotubule agents on c-myc oncogene expression depending on the cell lines used. Eur. J. Cancer 2000, 36:1043-1049.
-
(2000)
Eur. J. Cancer
, vol.36
, pp. 1043-1049
-
-
Bourgarel-Rey, V.1
El, K.S.2
Rimet, O.3
Bordas, B.4
Guigal, N.5
Braguer, D.6
Seree, E.7
Barra, Y.8
Briand, C.9
-
6
-
-
0035283038
-
Recruitment, activation and retention of caspases-9 and -3 by Apaf-1 apoptosome and associated XIAP complexes
-
Bratton S.B., Walker G., Srinivasula S.M., Sun X.M., Butterworth M., Alnemri E.S., Cohen G.M. Recruitment, activation and retention of caspases-9 and -3 by Apaf-1 apoptosome and associated XIAP complexes. EMBO J. 2001, 20:998-1009.
-
(2001)
EMBO J.
, vol.20
, pp. 998-1009
-
-
Bratton, S.B.1
Walker, G.2
Srinivasula, S.M.3
Sun, X.M.4
Butterworth, M.5
Alnemri, E.S.6
Cohen, G.M.7
-
8
-
-
0028979467
-
Pi 1 binding sites are negative regulators of bcl-2 expression in pre-B cells
-
Chen H.M., Boxer L.M. Pi 1 binding sites are negative regulators of bcl-2 expression in pre-B cells. Mol. Cell. Biol. 1995, 15:3840-3847.
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 3840-3847
-
-
Chen, H.M.1
Boxer, L.M.2
-
9
-
-
0034708821
-
Inhibition of caspase-3-mediated poly(ADP-ribose) polymerase (PARP) apoptotic cleavage by human PARP autoantibodies and effect on cells undergoing apoptosis
-
Decker P., Isenberg D., Muller S. Inhibition of caspase-3-mediated poly(ADP-ribose) polymerase (PARP) apoptotic cleavage by human PARP autoantibodies and effect on cells undergoing apoptosis. J. Biol. Chem. 2000, 275:9043-9046.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 9043-9046
-
-
Decker, P.1
Isenberg, D.2
Muller, S.3
-
10
-
-
0032885388
-
Mammalian caspases: structure, activation, substrates, and functions during apoptosis
-
Earnshaw W.C., Martins L.M., Kaufmann S.H. Mammalian caspases: structure, activation, substrates, and functions during apoptosis. Annu. Rev. Biochem. 1999, 68:383-424.
-
(1999)
Annu. Rev. Biochem.
, vol.68
, pp. 383-424
-
-
Earnshaw, W.C.1
Martins, L.M.2
Kaufmann, S.H.3
-
11
-
-
0043122940
-
AKT inhibition is associated with chemosensitisation in the pancreatic cancer cell line MIA-PaCa-2
-
Fahy B.N., Schlieman M., Virudachalam S., Bold R.J. AKT inhibition is associated with chemosensitisation in the pancreatic cancer cell line MIA-PaCa-2. Br. J. Cancer 2003, 89:391-397.
-
(2003)
Br. J. Cancer
, vol.89
, pp. 391-397
-
-
Fahy, B.N.1
Schlieman, M.2
Virudachalam, S.3
Bold, R.J.4
-
12
-
-
0037198274
-
NF-kappaB activates Bcl-2 expression in t(14;18) lymphoma cells
-
Heckman C.A., Mehew J.W., Boxer L.M. NF-kappaB activates Bcl-2 expression in t(14;18) lymphoma cells. Oncogene 2002, 21:3898-3908.
-
(2002)
Oncogene
, vol.21
, pp. 3898-3908
-
-
Heckman, C.A.1
Mehew, J.W.2
Boxer, L.M.3
-
13
-
-
65649135129
-
Naphthalimides and azonafides as promising anti-cancer agents
-
Ingrassia L., Lefranc F., Kiss R., Mijatovic T. Naphthalimides and azonafides as promising anti-cancer agents. Curr. Med. Chem. 2009, 16:1192-1213.
-
(2009)
Curr. Med. Chem.
, vol.16
, pp. 1192-1213
-
-
Ingrassia, L.1
Lefranc, F.2
Kiss, R.3
Mijatovic, T.4
-
14
-
-
0040298568
-
Caspase-3 is required for DNA fragmentation and morphological changes associated with apoptosis
-
Janicke R.U., Sprengart M.L., Wati M.R., Porter A.G. Caspase-3 is required for DNA fragmentation and morphological changes associated with apoptosis. J. Biol. Chem. 1998, 273:9357-9360.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 9357-9360
-
-
Janicke, R.U.1
Sprengart, M.L.2
Wati, M.R.3
Porter, A.G.4
-
15
-
-
79959719799
-
B1, a novel naphthalimide-based DNA intercalator, induces cell cycle arrest and apoptosis in HeLa cells via p53 activation
-
Liang X., Wu A.B., Xu Y.F., Xu K., Liu J.W., Qian X.H. B1, a novel naphthalimide-based DNA intercalator, induces cell cycle arrest and apoptosis in HeLa cells via p53 activation. Invest. New Drugs 2011, 29:646-658.
-
(2011)
Invest. New Drugs
, vol.29
, pp. 646-658
-
-
Liang, X.1
Wu, A.B.2
Xu, Y.F.3
Xu, K.4
Liu, J.W.5
Qian, X.H.6
-
16
-
-
44449092734
-
UNBS5162, a novel naphthalimide that decreases CXCL chemokine expression in experimental prostate cancers
-
Mijatovic T., Mahieu T., Bruyère C., De Nève N., Dewelle J., Simon G., Dehoux M.J.M., Aar E., Haibe-Kains B., Bontempi G., Decaestecker C., Quaquebeke E.V., Darro F., Kiss R. UNBS5162, a novel naphthalimide that decreases CXCL chemokine expression in experimental prostate cancers. Neoplasia 2008, 10:573-586.
-
(2008)
Neoplasia
, vol.10
, pp. 573-586
-
-
Mijatovic, T.1
Mahieu, T.2
Bruyère, C.3
De Nève, N.4
Dewelle, J.5
Simon, G.6
Dehoux, M.J.M.7
Aar, E.8
Haibe-Kains, B.9
Bontempi, G.10
Decaestecker, C.11
Quaquebeke, E.V.12
Darro, F.13
Kiss, R.14
-
17
-
-
0028292480
-
Identification of a p53-dependent negative response element in the bcl-2 gene
-
Miyashita T., Harigai M., Hanada M., Reed J.C. Identification of a p53-dependent negative response element in the bcl-2 gene. Cancer Res. 1994, 54:3131-3135.
-
(1994)
Cancer Res.
, vol.54
, pp. 3131-3135
-
-
Miyashita, T.1
Harigai, M.2
Hanada, M.3
Reed, J.C.4
-
18
-
-
0028335717
-
Tumor suppressor p53 is a regulator of bcl-2 and bax gene expression in vitro and in vivo
-
Miyashita T., Krajewski S., Krajewska M., Wang H.G., Lin H.K., Liebermann D.A., Hoffman B., Reed J.C. Tumor suppressor p53 is a regulator of bcl-2 and bax gene expression in vitro and in vivo. Oncogene 1994, 9:1799-1805.
-
(1994)
Oncogene
, vol.9
, pp. 1799-1805
-
-
Miyashita, T.1
Krajewski, S.2
Krajewska, M.3
Wang, H.G.4
Lin, H.K.5
Liebermann, D.A.6
Hoffman, B.7
Reed, J.C.8
-
19
-
-
0028883179
-
Tumor suppressor p53 is a direct transcriptional activator of the human bax gene
-
Miyashita T., Reed J.C. Tumor suppressor p53 is a direct transcriptional activator of the human bax gene. Cell 1995, 80:293-299.
-
(1995)
Cell
, vol.80
, pp. 293-299
-
-
Miyashita, T.1
Reed, J.C.2
-
20
-
-
34548540642
-
Highly efficient antitumor agents of heterocycles containing sulfur atom: linear and angular thiazonaphthalimides against human lung cancer cell in vitro
-
Qian X.H., Li Z.G., Yang Q. Highly efficient antitumor agents of heterocycles containing sulfur atom: linear and angular thiazonaphthalimides against human lung cancer cell in vitro. Bioorgan. Med. Chem. 2007, 15:6846-6851.
-
(2007)
Bioorgan. Med. Chem.
, vol.15
, pp. 6846-6851
-
-
Qian, X.H.1
Li, Z.G.2
Yang, Q.3
-
21
-
-
0023779204
-
Alternative promoters and exons, somatic mutation and deregulation of the Bcl-2-Ig fusion gene in lymphoma
-
Seto M., Jaeger U., Hockett R.D., Graninger W., Bennett S., Goldman P. Alternative promoters and exons, somatic mutation and deregulation of the Bcl-2-Ig fusion gene in lymphoma. EMBO J. 1988, 7:123-131.
-
(1988)
EMBO J.
, vol.7
, pp. 123-131
-
-
Seto, M.1
Jaeger, U.2
Hockett, R.D.3
Graninger, W.4
Bennett, S.5
Goldman, P.6
-
22
-
-
2142700030
-
Carboplatin induces apoptotic cell death through downregulation of constitutively active nuclear factor-kappaB in human HPV-18 E6-positive HEp-2 cells
-
Singh S., Bhat M.K. Carboplatin induces apoptotic cell death through downregulation of constitutively active nuclear factor-kappaB in human HPV-18 E6-positive HEp-2 cells. Biochem. Biophys. Res. Commun. 2004, 318:346-353.
-
(2004)
Biochem. Biophys. Res. Commun.
, vol.318
, pp. 346-353
-
-
Singh, S.1
Bhat, M.K.2
-
23
-
-
34548138904
-
2,2,2-Trichloro-N-({2-[2-(dimethylamino)ethyl]-1,3-dioxo-2,3-dihydro-1H-benzo[de]isoquinolin-5-yl}carbamoyl)acetamide (UNBS3157), a novel nonhematotoxic naphthalimide derivative with potent antitumor activity
-
Van Q.E., Mahieu T., Dumont P., Dewelle J., Ribaucour F., Simon G., Sauvage S., Gaussin J.F., Tuti J., El Yazidi M., Van Vynckt F., Mijatovic T., Lefranc F., Darro F., Kiss R. 2,2,2-Trichloro-N-({2-[2-(dimethylamino)ethyl]-1,3-dioxo-2,3-dihydro-1H-benzo[de]isoquinolin-5-yl}carbamoyl)acetamide (UNBS3157), a novel nonhematotoxic naphthalimide derivative with potent antitumor activity. J. Med. Chem. 2007, 50:4122-4134.
-
(2007)
J. Med. Chem.
, vol.50
, pp. 4122-4134
-
-
Van, Q.E.1
Mahieu, T.2
Dumont, P.3
Dewelle, J.4
Ribaucour, F.5
Simon, G.6
Sauvage, S.7
Gaussin, J.F.8
Tuti, J.9
El, Y.M.10
Van Vynckt, F.11
Mijatovic, T.12
Lefranc, F.13
Darro, F.14
Kiss, R.15
-
24
-
-
36549053494
-
In vitro cytotoxic potential of Polyalthia longifolia on human cancer cell lines and induction of apoptosis through mitochondrial-dependent pathway in HL-60 cells
-
Verma M., Singh S.K., Bhushan S., Sharma V.K., Datt P., Kapahi B.K., Saxena A.K. In vitro cytotoxic potential of Polyalthia longifolia on human cancer cell lines and induction of apoptosis through mitochondrial-dependent pathway in HL-60 cells. Chem. Biol. Interact. 2008, 171:45-56.
-
(2008)
Chem. Biol. Interact.
, vol.171
, pp. 45-56
-
-
Verma, M.1
Singh, S.K.2
Bhushan, S.3
Sharma, V.K.4
Datt, P.5
Kapahi, B.K.6
Saxena, A.K.7
-
25
-
-
69849107875
-
M2-A induces apoptosis and G2-M arrest via inhibiting PI3 K/Akt pathway in HL60 cells
-
Wang J., Wu A.B., Xu Y.F., Liu J.W., Qian X.H. M2-A induces apoptosis and G2-M arrest via inhibiting PI3 K/Akt pathway in HL60 cells. Cancer Lett. 2009, 283:193-202.
-
(2009)
Cancer Lett.
, vol.283
, pp. 193-202
-
-
Wang, J.1
Wu, A.B.2
Xu, Y.F.3
Liu, J.W.4
Qian, X.H.5
-
26
-
-
0029810469
-
Induction of bcl-2 expression by phosphorylated CREB proteins during B-cell activation and rescue from apoptosis
-
Wilson B.E., Mochon E., Boxer L.M. Induction of bcl-2 expression by phosphorylated CREB proteins during B-cell activation and rescue from apoptosis. Mol. Cell. Biol. 1996, 16:5546-5556.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 5546-5556
-
-
Wilson, B.E.1
Mochon, E.2
Boxer, L.M.3
-
27
-
-
0035843156
-
Negative regulation of bcl-2 expression by p53 in hematopoietic cells
-
Wu Y., Mehew J.W., Heckman C.A., Arcinas M., Boxer L.M. Negative regulation of bcl-2 expression by p53 in hematopoietic cells. Oncogene 2001, 20:240-251.
-
(2001)
Oncogene
, vol.20
, pp. 240-251
-
-
Wu, Y.1
Mehew, J.W.2
Heckman, C.A.3
Arcinas, M.4
Boxer, L.M.5
-
28
-
-
33847400139
-
R16, a novel amonafide analogue, induces apoptosis and G2-M arrest via poisoning topoisomerase II
-
Zhu H., Huang M., Yang F., Chen Y., Miao Z.H., Qian X.H., Xu Y.F., Qin Y.X., Luo H.B., Shen X., Geng M.Y., Cai Y.J., Ding J. R16, a novel amonafide analogue, induces apoptosis and G2-M arrest via poisoning topoisomerase II. Mol. Cancer Ther. 2007, 6:484-495.
-
(2007)
Mol. Cancer Ther.
, vol.6
, pp. 484-495
-
-
Zhu, H.1
Huang, M.2
Yang, F.3
Chen, Y.4
Miao, Z.H.5
Qian, X.H.6
Xu, Y.F.7
Qin, Y.X.8
Luo, H.B.9
Shen, X.10
Geng, M.Y.11
Cai, Y.J.12
Ding, J.13
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