Characterization of a PLP-overexpressing transgenic rat, a model for the connatal form of Pelizaeus-Merzbacher disease

Neurobiology of Disease

Volumn 44, Issue 2, 2011, Pages 231-238

  Mayer, Joshua A ^a   Larsen, Eric C ^a   Kondo, Yoichi ^a   Duncan, Ian D ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

Apoptosis; Connatal PMD; Gene duplication; Myelination; Pelizaeus Merzbacher disease; Plp1; Proteolipid protein

Indexed keywords

MYELIN PROTEIN; PROTEOLIPID PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL DEATH; CONTROLLED STUDY; DISEASE CLASSIFICATION; DISEASE SEVERITY; GENE DOSAGE; GENE DUPLICATION; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; MOLECULAR BIOLOGY; NICK END LABELING; NONHUMAN; OLIGODENDROGLIA; PELIZAEUS MERZBACHER DISEASE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSGENIC RAT; WESTERN BLOTTING; WILD TYPE;

ANIMALS; ANIMALS, NEWBORN; BIOLOGICAL MARKERS; DISEASE MODELS, ANIMAL; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MYELIN PROTEOLIPID PROTEIN; MYELIN SHEATH; PELIZAEUS-MERZBACHER DISEASE; RATS; RATS, INBRED LEW; RATS, TRANSGENIC; RATS, WISTAR;

EID: 80052293124     PISSN: 09699961     EISSN: 1095953X     Source Type: Journal    
DOI: 10.1016/j.nbd.2011.07.007     Document Type: Article

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