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Volumn 192, Issue , 2011, Pages 507-514

Uncoupling protein 2 knockout exacerbates depression-like behaviors in mice via enhancing inflammatory response

Author keywords

Chronic mild stress; Nuclear factor B; Tumor necrosis factor alpha; Uncoupling protein 2

Indexed keywords

CORTICOSTERONE; MESSENGER RNA; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA; UNCOUPLING PROTEIN 2;

EID: 80052263109     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2011.05.047     Document Type: Article
Times cited : (22)

References (56)
  • 1
    • 77953439761 scopus 로고    scopus 로고
    • Alterations in monoamine levels and oxidative systems in frontal cortex, striatum, and hippocampus of the rat brain during chronic unpredictable stress
    • Ahmad A., Rasheed N., Banu N., Palit G. Alterations in monoamine levels and oxidative systems in frontal cortex, striatum, and hippocampus of the rat brain during chronic unpredictable stress. Stress 2010, 13:355-364.
    • (2010) Stress , vol.13 , pp. 355-364
    • Ahmad, A.1    Rasheed, N.2    Banu, N.3    Palit, G.4
  • 2
    • 27644448810 scopus 로고    scopus 로고
    • Mitochondrial uncoupling proteins in the CNS: in support of function and survival
    • Andrews Z.B., Diano S., Horvath T.L. Mitochondrial uncoupling proteins in the CNS: in support of function and survival. Nat Rev Neurosci 2005, 6:829-840.
    • (2005) Nat Rev Neurosci , vol.6 , pp. 829-840
    • Andrews, Z.B.1    Diano, S.2    Horvath, T.L.3
  • 6
    • 14844355112 scopus 로고    scopus 로고
    • Major depression and risk of depressive symptomatology associated with short-term and low-dose interferon-alpha treatment
    • Beratis S., Katrivanou A., Georgiou S., Monastirli A., Pasmatzi E., Gourzis P., Tsambaos D. Major depression and risk of depressive symptomatology associated with short-term and low-dose interferon-alpha treatment. J Psychosom Res 2005, 58:15-18.
    • (2005) J Psychosom Res , vol.58 , pp. 15-18
    • Beratis, S.1    Katrivanou, A.2    Georgiou, S.3    Monastirli, A.4    Pasmatzi, E.5    Gourzis, P.6    Tsambaos, D.7
  • 10
    • 33746303035 scopus 로고    scopus 로고
    • Cytokine, sickness behavior, and depression
    • Dantzer R. Cytokine, sickness behavior, and depression. Neurol Clin 2006, 24:441-460.
    • (2006) Neurol Clin , vol.24 , pp. 441-460
    • Dantzer, R.1
  • 12
    • 79851507642 scopus 로고    scopus 로고
    • Incidence of major depressive episode correlates with elevation of substate region of residence
    • Delmastro K., Hellem T., Kim N., Kondo D., Sung Y.H., Renshaw P.F. Incidence of major depressive episode correlates with elevation of substate region of residence. J Affect Disord 2011, 129:376-379.
    • (2011) J Affect Disord , vol.129 , pp. 376-379
    • Delmastro, K.1    Hellem, T.2    Kim, N.3    Kondo, D.4    Sung, Y.H.5    Renshaw, P.F.6
  • 13
    • 0033392903 scopus 로고    scopus 로고
    • Mitochondrial uncoupling: role of uncoupling protein anion carriers and relationship to thermogenesis and weight control "the benefits of losing control"
    • Diehl A.M., Hoek J.B. Mitochondrial uncoupling: role of uncoupling protein anion carriers and relationship to thermogenesis and weight control "the benefits of losing control". J Bioenerg Biomembr 1999, 31:493-506.
    • (1999) J Bioenerg Biomembr , vol.31 , pp. 493-506
    • Diehl, A.M.1    Hoek, J.B.2
  • 15
    • 37649024444 scopus 로고    scopus 로고
    • Role of uncoupling protein UCP2 in cell-mediated immunity: how macrophage-mediated insulitis is accelerated in a model of autoimmune diabetes
    • Emre Y., Hurtaud C., Karaca M., Nubel T., Zavala F., Ricquier D. Role of uncoupling protein UCP2 in cell-mediated immunity: how macrophage-mediated insulitis is accelerated in a model of autoimmune diabetes. Proc Natl Acad Sci U S A 2007, 104:19085-19090.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 19085-19090
    • Emre, Y.1    Hurtaud, C.2    Karaca, M.3    Nubel, T.4    Zavala, F.5    Ricquier, D.6
  • 16
    • 33847698059 scopus 로고    scopus 로고
    • Mitochondria contribute to LPS-induced MAPK activation via uncoupling protein UCP2 in macrophages
    • Emre Y., Hurtaud C., Nubel T., Criscuolo F., Ricquier D., Cassard-Doulcier A.M. Mitochondria contribute to LPS-induced MAPK activation via uncoupling protein UCP2 in macrophages. Biochem J 2007, 402:271-278.
    • (2007) Biochem J , vol.402 , pp. 271-278
    • Emre, Y.1    Hurtaud, C.2    Nubel, T.3    Criscuolo, F.4    Ricquier, D.5    Cassard-Doulcier, A.M.6
  • 19
    • 56349103640 scopus 로고    scopus 로고
    • Why antidepressants are not antidepressants: STEP-BD, STAR*D, and the return of neurotic depression
    • Ghaemi S.N. Why antidepressants are not antidepressants: STEP-BD, STAR*D, and the return of neurotic depression. Bipolar Disord 2008, 10:957-968.
    • (2008) Bipolar Disord , vol.10 , pp. 957-968
    • Ghaemi, S.N.1
  • 20
    • 78650511776 scopus 로고    scopus 로고
    • Chronic mild stress damages mitochondrial ultrastructure and function in mouse brain
    • Gong Y., Chai Y., Ding J.H., Sun X.L., Hu G. Chronic mild stress damages mitochondrial ultrastructure and function in mouse brain. Neurosci Lett 2011, 488:76-80.
    • (2011) Neurosci Lett , vol.488 , pp. 76-80
    • Gong, Y.1    Chai, Y.2    Ding, J.H.3    Sun, X.L.4    Hu, G.5
  • 22
    • 34248563489 scopus 로고    scopus 로고
    • Extracellular levels of serotonin and GABA in the hippocampus after chronic mild stress in rats. A microdialysis study in an animal model of depression
    • Gronli J., Fiske E., Murison R., Bjorvatn B., Sorensen E., Ursin R., Portas C.M. Extracellular levels of serotonin and GABA in the hippocampus after chronic mild stress in rats. A microdialysis study in an animal model of depression. Behav Brain Res 2007, 181:42-51.
    • (2007) Behav Brain Res , vol.181 , pp. 42-51
    • Gronli, J.1    Fiske, E.2    Murison, R.3    Bjorvatn, B.4    Sorensen, E.5    Ursin, R.6    Portas, C.M.7
  • 23
    • 78049481928 scopus 로고    scopus 로고
    • Deletion of mitochondrial uncoupling protein-2 increases ischemic brain damage after transient focal ischemia by altering gene expression patterns and enhancing inflammatory cytokines
    • Haines B.A., Mehta S.L., Pratt S.M., Warden C.H., Li P.A. Deletion of mitochondrial uncoupling protein-2 increases ischemic brain damage after transient focal ischemia by altering gene expression patterns and enhancing inflammatory cytokines. J Cereb Blood Flow Metab 2010, 30:1825-1833.
    • (2010) J Cereb Blood Flow Metab , vol.30 , pp. 1825-1833
    • Haines, B.A.1    Mehta, S.L.2    Pratt, S.M.3    Warden, C.H.4    Li, P.A.5
  • 24
    • 0142139276 scopus 로고    scopus 로고
    • The mechanisms of immune-to-brain communication in inflammation as a drug target
    • Hosoi T., Okuma Y., Nomura Y. The mechanisms of immune-to-brain communication in inflammation as a drug target. Curr Drug Targets Inflamm Allergy 2002, 1:257-262.
    • (2002) Curr Drug Targets Inflamm Allergy , vol.1 , pp. 257-262
    • Hosoi, T.1    Okuma, Y.2    Nomura, Y.3
  • 25
    • 17644367102 scopus 로고    scopus 로고
    • Nelumbinis Semen reverses a decrease in hippocampal 5-HT release induced by chronic mild stress in rats
    • Kang M., Pyun K.H., Jang C.G., Kim H., Bae H., Shim I. Nelumbinis Semen reverses a decrease in hippocampal 5-HT release induced by chronic mild stress in rats. J Pharm Pharmacol 2005, 57:651-656.
    • (2005) J Pharm Pharmacol , vol.57 , pp. 651-656
    • Kang, M.1    Pyun, K.H.2    Jang, C.G.3    Kim, H.4    Bae, H.5    Shim, I.6
  • 27
    • 0035096807 scopus 로고    scopus 로고
    • Prolonged desipramine treatment increases the production of interleukin-10, an anti-inflammatory cytokine, in C57BL/6 mice subjected to the chronic mild stress model of depression
    • Kubera M., Maes M., Holan V., Basta-Kaim A., Roman A., Shani J. Prolonged desipramine treatment increases the production of interleukin-10, an anti-inflammatory cytokine, in C57BL/6 mice subjected to the chronic mild stress model of depression. J Affect Disord 2001, 63:171-178.
    • (2001) J Affect Disord , vol.63 , pp. 171-178
    • Kubera, M.1    Maes, M.2    Holan, V.3    Basta-Kaim, A.4    Roman, A.5    Shani, J.6
  • 28
    • 69949161473 scopus 로고    scopus 로고
    • Depression and antidepressants: molecular and cellular aspects
    • Lanni C., Govoni S., Lucchelli A., Boselli C. Depression and antidepressants: molecular and cellular aspects. Cell Mol Life Sci 2009, 66:2985-3008.
    • (2009) Cell Mol Life Sci , vol.66 , pp. 2985-3008
    • Lanni, C.1    Govoni, S.2    Lucchelli, A.3    Boselli, C.4
  • 29
    • 31844432926 scopus 로고    scopus 로고
    • The HPA and immune axes in stress: the involvement of the serotonergic system
    • Leonard B.E. The HPA and immune axes in stress: the involvement of the serotonergic system. Eur Psychiatry 2005, 20(Suppl 3):S302-S306.
    • (2005) Eur Psychiatry , vol.20 , Issue.SUPPL 3
    • Leonard, B.E.1
  • 30
    • 48049084135 scopus 로고    scopus 로고
    • The cytokine hypothesis of depression: inflammation, oxidative & nitrosative stress (IO&NS) and leaky gut as new targets for adjunctive treatments in depression
    • Maes M. The cytokine hypothesis of depression: inflammation, oxidative & nitrosative stress (IO&NS) and leaky gut as new targets for adjunctive treatments in depression. Neuro Endocrinol Lett 2008, 29:287-291.
    • (2008) Neuro Endocrinol Lett , vol.29 , pp. 287-291
    • Maes, M.1
  • 31
    • 33644639853 scopus 로고    scopus 로고
    • The emerging functions of UCP2 in health, disease, and therapeutics
    • Mattiasson G., Sullivan P.G. The emerging functions of UCP2 in health, disease, and therapeutics. Antioxid Redox Signal 2006, 8:1-38.
    • (2006) Antioxid Redox Signal , vol.8 , pp. 1-38
    • Mattiasson, G.1    Sullivan, P.G.2
  • 32
    • 33750633946 scopus 로고    scopus 로고
    • Effects of unpredictable chronic mild stress on anxiety and depression-like behavior in mice
    • Mineur Y.S., Belzung C., Crusio W.E. Effects of unpredictable chronic mild stress on anxiety and depression-like behavior in mice. Behav Brain Res 2006, 175:43-50.
    • (2006) Behav Brain Res , vol.175 , pp. 43-50
    • Mineur, Y.S.1    Belzung, C.2    Crusio, W.E.3
  • 33
    • 18144377756 scopus 로고    scopus 로고
    • Characterization of the differential expression of uncoupling protein 2 and ROS production in differentiated mouse macrophage-cells (Mm1) and the progenitor cells (M1)
    • Nishio K., Qiao S., Yamashita H. Characterization of the differential expression of uncoupling protein 2 and ROS production in differentiated mouse macrophage-cells (Mm1) and the progenitor cells (M1). J Mol Histol 2005, 36:35-44.
    • (2005) J Mol Histol , vol.36 , pp. 35-44
    • Nishio, K.1    Qiao, S.2    Yamashita, H.3
  • 34
    • 0030922017 scopus 로고    scopus 로고
    • Pituitary-adrenal cortical axis measures as predictors of sustained remission in major depression
    • O'Toole S.M., Sekula L.K., Rubin R.T. Pituitary-adrenal cortical axis measures as predictors of sustained remission in major depression. Biol Psychiatry 1997, 42:85-89.
    • (1997) Biol Psychiatry , vol.42 , pp. 85-89
    • O'Toole, S.M.1    Sekula, L.K.2    Rubin, R.T.3
  • 35
    • 70449376943 scopus 로고    scopus 로고
    • Cytokines and glucocorticoid receptor signaling. Relevance to major depression
    • Pace T.W., Miller A.H. Cytokines and glucocorticoid receptor signaling. Relevance to major depression. Ann N Y Acad Sci 2009, 1179:86-105.
    • (2009) Ann N Y Acad Sci , vol.1179 , pp. 86-105
    • Pace, T.W.1    Miller, A.H.2
  • 36
    • 33749072534 scopus 로고    scopus 로고
    • Increased stress-induced inflammatory responses in male patients with major depression and increased early life stress
    • Pace T.W., Mletzko T.C., Alagbe O., Musselman D.L., Nemeroff C.B., Miller A.H., Heim C.M. Increased stress-induced inflammatory responses in male patients with major depression and increased early life stress. Am J Psychiatry 2006, 163:1630-1633.
    • (2006) Am J Psychiatry , vol.163 , pp. 1630-1633
    • Pace, T.W.1    Mletzko, T.C.2    Alagbe, O.3    Musselman, D.L.4    Nemeroff, C.B.5    Miller, A.H.6    Heim, C.M.7
  • 37
    • 33751013017 scopus 로고    scopus 로고
    • Forced swimming test increases superoxide anion positive cells and angiotensin II positive cells in the cerebrum and cerebellum of the rat
    • Pedreanez A., Arcaya J.L., Carrizo E., Mosquera J. Forced swimming test increases superoxide anion positive cells and angiotensin II positive cells in the cerebrum and cerebellum of the rat. Brain Res Bull 2006, 71:18-22.
    • (2006) Brain Res Bull , vol.71 , pp. 18-22
    • Pedreanez, A.1    Arcaya, J.L.2    Carrizo, E.3    Mosquera, J.4
  • 38
    • 60649099360 scopus 로고    scopus 로고
    • Depression and pain: prevalence and clinical implication
    • Pelissolo A. Depression and pain: prevalence and clinical implication. Presse Med 2009, 38:385-391.
    • (2009) Presse Med , vol.38 , pp. 385-391
    • Pelissolo, A.1
  • 39
    • 14644393659 scopus 로고    scopus 로고
    • Neuropsychiatric adverse effects of interferon-alpha: recognition and management
    • Raison C.L., Demetrashvili M., Capuron L., Miller A.H. Neuropsychiatric adverse effects of interferon-alpha: recognition and management. CNS Drugs 2005, 19:105-123.
    • (2005) CNS Drugs , vol.19 , pp. 105-123
    • Raison, C.L.1    Demetrashvili, M.2    Capuron, L.3    Miller, A.H.4
  • 42
    • 0032787663 scopus 로고    scopus 로고
    • Hypothalamo-pituitary-adrenal cortical responses to low-dose physostigmine and arginine vasopressin administration: sex differences between major depressives and matched control subjects
    • Rubin R.T., O'Toole S.M., Rhodes M.E., Sekula L.K., Czambel R.K. Hypothalamo-pituitary-adrenal cortical responses to low-dose physostigmine and arginine vasopressin administration: sex differences between major depressives and matched control subjects. Psychiatry Res 1999, 89:1-20.
    • (1999) Psychiatry Res , vol.89 , pp. 1-20
    • Rubin, R.T.1    O'Toole, S.M.2    Rhodes, M.E.3    Sekula, L.K.4    Czambel, R.K.5
  • 45
    • 59849096319 scopus 로고    scopus 로고
    • Chronic mild stress (CMS) in mice: of anhedonia, "anomalous anxiolysis" and activity
    • Schweizer M.C., Henniger M.S., Sillaber I. Chronic mild stress (CMS) in mice: of anhedonia, "anomalous anxiolysis" and activity. PLoS One 2009, 4:e4326.
    • (2009) PLoS One , vol.4
    • Schweizer, M.C.1    Henniger, M.S.2    Sillaber, I.3
  • 46
    • 60249092083 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor: the neurotrophin hypothesis of psychopathology
    • Stein D.J., Daniels W.M., Savitz J., Harvey B.H. Brain-derived neurotrophic factor: the neurotrophin hypothesis of psychopathology. CNS Spectr 2008, 13:945-949.
    • (2008) CNS Spectr , vol.13 , pp. 945-949
    • Stein, D.J.1    Daniels, W.M.2    Savitz, J.3    Harvey, B.H.4
  • 47
    • 34249897537 scopus 로고    scopus 로고
    • Risk factors for vascular dementia in elderly psychiatric outpatients with preserved cognitive functions
    • Stella F., Banzato C.E., Gasparetto Se E.V., Scudeler J.L., Pacheco J.L., Kajita R.T. Risk factors for vascular dementia in elderly psychiatric outpatients with preserved cognitive functions. J Neurol Sci 2007, 257:247-249.
    • (2007) J Neurol Sci , vol.257 , pp. 247-249
    • Stella, F.1    Banzato, C.E.2    Gasparetto Se, E.V.3    Scudeler, J.L.4    Pacheco, J.L.5    Kajita, R.T.6
  • 48
    • 48049094446 scopus 로고    scopus 로고
    • Drug-dependent requirement of hippocampal neurogenesis in a model of depression and of antidepressant reversal
    • Surget A., Saxe M., Leman S., Ibarguen-Vargas Y., Chalon S., Griebel G., Hen R., Belzung C. Drug-dependent requirement of hippocampal neurogenesis in a model of depression and of antidepressant reversal. Biol Psychiatry 2008, 64:293-301.
    • (2008) Biol Psychiatry , vol.64 , pp. 293-301
    • Surget, A.1    Saxe, M.2    Leman, S.3    Ibarguen-Vargas, Y.4    Chalon, S.5    Griebel, G.6    Hen, R.7    Belzung, C.8
  • 51
    • 67650713695 scopus 로고    scopus 로고
    • Evaluating atypical antipsychotics in the treatment of refractory depression
    • Thase M.E. Evaluating atypical antipsychotics in the treatment of refractory depression. J Clin Psychiatry 2009, 70:e14.
    • (2009) J Clin Psychiatry , vol.70
    • Thase, M.E.1
  • 52
    • 40449103537 scopus 로고    scopus 로고
    • Studies of UCP2 transgenic and knockout mice reveal that liver UCP2 is not essential for the antiobesity effects of fish oil
    • Tsuboyama-Kasaoka N., Sano K., Shozawa C., Osaka T., Ezaki O. Studies of UCP2 transgenic and knockout mice reveal that liver UCP2 is not essential for the antiobesity effects of fish oil. Am J Physiol Endocrinol Metab 2008, 294:E600-E606.
    • (2008) Am J Physiol Endocrinol Metab , vol.294
    • Tsuboyama-Kasaoka, N.1    Sano, K.2    Shozawa, C.3    Osaka, T.4    Ezaki, O.5
  • 54
    • 33646508138 scopus 로고    scopus 로고
    • Uncoupling protein 2 has protective function during experimental autoimmune encephalomyelitis
    • Vogler S., Pahnke J., Rousset S., Ricquier D., Moch H., Miroux B., Ibrahim S.M. Uncoupling protein 2 has protective function during experimental autoimmune encephalomyelitis. Am J Pathol 2006, 168:1570-1575.
    • (2006) Am J Pathol , vol.168 , pp. 1570-1575
    • Vogler, S.1    Pahnke, J.2    Rousset, S.3    Ricquier, D.4    Moch, H.5    Miroux, B.6    Ibrahim, S.M.7


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