Cis-9,trans-11-conjugated linoleic acid promotes neuronal differentiation through regulation of Hes6 mRNA and cell cycle in cultured neural stem cells

Prostaglandins Leukotrienes and Essential Fatty Acids

Volumn 85, Issue 3-4, 2011, Pages 163-169

  Okui, Toshiyuki ^a   Hashimoto, Michio ^a   Katakura, Masanori ^a   Shido, Osamu ^a  

^a SHIMANE UNIVERSITY FACULTY OF MEDICINE   (Japan)

Author keywords

Cell cycle; Conjugated linoleic acid; Neural stem cell; Neurogenesis

Indexed keywords

BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; CONJUGATED LINOLEIC ACID; CYCLIN DEPENDENT KINASE INHIBITOR; CYCLIN DEPENDENT KINASE INHIBITOR 1; CYCLIN DEPENDENT KINASE INHIBITOR 1B; HAIRY AND ENHANCER OF SPLIT 6 PROTEIN; LINOLEIC ACID; MESSENGER RNA; MICROTUBULE ASSOCIATED PROTEIN 2; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL CYCLE REGULATION; CELL CYCLE S PHASE; CONTROLLED STUDY; DRUG STRUCTURE; FLOW CYTOMETRY; GENE EXPRESSION; IMMUNOFLUORESCENCE TEST; NERVE CELL CULTURE; NERVE CELL DIFFERENTIATION; NEURAL STEM CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RAT; REAL TIME POLYMERASE CHAIN REACTION;

ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CELL CYCLE CHECKPOINTS; CELL DIFFERENTIATION; CELL PROLIFERATION; CELLS, CULTURED; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLIN-DEPENDENT KINASE INHIBITOR P27; GENE EXPRESSION; LINOLEIC ACID; LINOLEIC ACIDS, CONJUGATED; NEURAL STEM CELLS; NEURONS; RATS; RNA, MESSENGER;

ANIMALIA;

EID: 80052262699     PISSN: 09523278     EISSN: 15322823     Source Type: Journal    
DOI: 10.1016/j.plefa.2011.06.001     Document Type: Article

References (40)

1. Yu L. Free radical scavenging properties of conjugated linoleic acids. J. Agric. Food Chem. 2001, 49:3452-3456.
2. Kepler C.R., Hirons K.P., McNeill J.J., Tove S.B. Intermediates and products of the biohydrogenation of linoleic acid by Butyrinvibrio fibrisolvens. J. Biol. Chem. 1966, 241:1350-1354.
3. Griinari J.M., Corl B.A., Lacy S.H., Chouinard P.Y., Nurmela K.V., Bauman D.E. Conjugated linoleic acid is synthesized endogenously in lactating dairy cows by Delta(9)-desaturase. J. Nutr. 2000, 130:2285-2291.
4. Bhattacharya A., Banu J., Rahman M., Causey J., Fernandes G. Biological effects of conjugated linoleic acids in health and disease. J. Nutr. Biochem. 2006, 17:789-810.
5. Sikorski A.M., Hebert N., Swain R.A. Conjugated linoleic acid (CLA) inhibits new vessel growth in the mammalian brain. Brain Res. 2008, 1213:35-40.
6. Fa M., Diana A., Carta G., et al. Incorporation and metabolism of c9,t11 and t10,c12 conjugated linoleic acid (CLA) isomers in rat brain. Biochim. Biophys. Acta 1736, 2005:61-66.
7. Alasnier C., Berdeaux O., Chardigny J.M., Sebedio J.L. Fatty acid composition and conjugated linoleic acid content of different tissues in rats fed individual conjugated linoleic acid isomers given as triacylglycerols small star, filled. J. Nutr. Biochem. 2002, 13:337-345.
8. Hashimoto M., Tanabe Y., Fujii Y., Kikuta T., Shibata H., Shido O. Chronic administration of docosahexaenoic acid ameliorates the impairment of spatial cognition learning ability in amyloid Β-infused rats. J. Nutr. 2005, 135:549-555.
9. Kawakita E., Hashimoto M., Shido O. Docosahexaenoic acid promotes neurogenesis in vitro and in vivo. Neuroscience 2006, 139:991-997.
10. Hashimoto M., Hossain S., Tanabe Y., et al. The protective effect of dietary eicosapentaenoic acid against impairment of spatial cognition learning ability in rats infused with amyloid Β (1-40). J. Nutr. Biochem. 2009, 20:965-973.
11. Adibhatla R.M., Hatcher J.F. Altered lipid metabolism in brain injury and disorders. Subcell. Biochem. 2008, 49:241-268.
12. Maekawa M., Takashima N., Matsumata M., et al. Arachidonic acid drives postnatal neurogenesis and elicits a beneficial effect on prepulse inhibition, a biological trait of psychiatric illnesses. PLoS One 2009, 4:e5085.
13. Temple S. The development of neural stem cells. Nature 2001, 414:112-117.
14. Reh T.A. Neural stem cells: form and function. Nat. Neurosci. 2002, 5:392-394.
15. Song H.J., Stevens C.F., Gage F.H. Neural stem cells from adult hippocampus develop essential properties of functional CNS neurons. Nat. Neurosci. 2002, 5:438-445.
16. Qian X., Shen Q., Goderie S.K., et al. Timing of CNS cell generation: a programmed sequence of neuron and glial cell production from isolated murine cortical stem cells. Neuron 2000, 28:69-80.
17. Kageyama R., Ohtsuka T., Hatakeyama J., Ohsawa R. Roles of bHLH genes in neural stem cell differentiation. Exp. Cell Res. 2005, 306:343-348.
18. Lee J.E. Basic helix-loop-helix genes in neural development. Curr. Opin. Neurobiol. 1997, 7:13-20.
19. Kageyama R., Ohtsuka T., Tomita K. The bHLH gene Hes1 regulates differentiation of multiple cell types. Mol. Cells 2000, 10:1-7.
20. Yoshikawa K. Cell cycle regulators in neural stem cells and postmitotic neurons. Neurosci. Res. 2000, 37:1-14.
21. Kim H.J., Hida H., Jung C.G., Miura Y., Nishino H. Treatment with deferoxamine increases neurons from neural stem/progenitor cells. Brain Res. 2006, 1092:1-15.
22. Cunningham J.J., Roussel M.F. Cyclin-dependent kinase inhibitors in the development of the central nervous system. Cell Growth Differ. 2001, 12:387-396.
23. Sherr C.J., Roberts J.M. CDK inhibitors: positive and negative regulators of G1-phase progression. Genes Dev. 1999, 13:1501-1512.
24. Reynolds B.A., Weiss S. Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system. Science 1992, 255:1707-1710.
25. Katakura M., Hashimoto M., Shahdat H.M., et al. Docosahexaenoic acid promotes neuronal differentiation by regulating basic helix-loop-helix transcription factors and cell cycle in neural stem cells. Neuroscience 2009, 160:651-660.
26. Kageyama R., Ishibashi M., Takebayashi K., Tomita K. bHLH transcription factors and mammalian neuronal differentiation. Int. J. Biochem. Cell Biol. 1997, 29:1389-1399.
27. Chae J.H., Stein G.H., Lee J.E. NeuroD: the predicted and the surprising. Mol. Cells 2004, 18:271-288.
28. Ohtsuka T., Sakamoto M., Guillemot F., Kageyama R. Roles of the basic helix-loop-helix genes Hes1 and Hes5 in expansion of neural stem cells of the developing brain. J. Biol. Chem. 2001, 276:30467-30474.
29. Ishibashi M., Moriyoshi K., Sasai Y., Shiota K., Nakanishi S., Kageyama R. Persistent expression of helix-loop-helix factor HES-1 prevents mammalian neural differentiation in the central nervous system. Embo. J. 1994, 13:1799-1805.
30. Sasai Y., Kageyama R., Tagawa Y., Shigemoto R., Nakanishi S. Two mammalian helix-loop-helix factors structurally related to Drosophila hairy and enhancer of split. Genes Dev. 1992, 6:2620-2634.
31. Chen H., Thiagalingam A., Chopra H., et al. Conservation of the Drosophila lateral inhibition pathway in human lung cancer: a hairy-related protein (HES-1) directly represses achaete-scute homolog-1 expression. Proc. Natl. Acad. Sci. USA 1997, 94:5355-5360.
32. Gratton M.O., Torban E., Jasmin S.B., Theriault F.M., German M.S., Stifani S. Hes6 promotes cortical neurogenesis and inhibits Hes1 transcription repression activity by multiple mechanisms. Mol. Cell Biol. 2003, 23:6922-6935.
33. Eun B., Lee Y., Hong S., et al. Hes6 controls cell proliferation via interaction with cAMP-response element-binding protein-binding protein in the promyelocytic leukemia nuclear body. J. Biol. Chem. 2008, 283:5939-5949.
34. Galderisi U., Jori F.P., Giordano A. Cell cycle regulation and neural differentiation. Oncogene 2003, 22:5208-5219.
35. Kemp M.Q., Jeffy B.D., Romagnolo D.F. Conjugated linoleic acid inhibits cell proliferation through a p53-dependent mechanism: effects on the expression of G1-restriction points in breast and colon cancer cells. J. Nutr. 2003, 133:3670-3677.
36. Speidel D. Transcription-independent p53 apoptosis: an alternative route to death. Trends Cell Biol. 2010, 20:14-24.
37. Gamoh S., Hashimoto M., Sugioka K., et al. Chronic administration of docosahexaenoic acid improves reference memory-related learning ability in young rats. Neuroscience 1999, 93:237-241.
38. Gamoh S., Hashimoto M., Hossain S., Masumura S. Chronic administration of docosahexaenoic acid improves the performance of radial arm maze task in aged rats. Clin. Exp. Pharmacol. Physiol. 2001, 28:266-270.
39. Hashimoto M., Hossain S., Shimada T., et al. Docosahexaenoic acid provides protection from impairment of learning ability in Alzheimer's disease model rats. J. Neurochem. 2002, 81:1084-1091.
40. Bae S., Bessho Y., Hojo M., Kageyama R. The bHLH gene Hes6, an inhibitor of Hes1, promotes neuronal differentiation. Development 2000, 127:2933-2943.