Chemo-enzymatic synthesis of ester-linked docetaxel-monosaccharide conjugates as water-soluble prodrugs

Molecules

Volumn 16, Issue 8, 2011, Pages 6769-6777

  Shimoda, Kei ^a   Kubota, Naoji ^a  

^a OITA UNIVERSITY   (Japan)

Author keywords

Chemo enzymatic synthesis; Cytotoxicity; Docetaxel; Ester linker; Glycoside; Prodrug

Indexed keywords

ANTINEOPLASTIC AGENT; BETA GALACTOSIDASE; DOCETAXEL; ESTER; EXO 1,4 BETA D XYLOSIDASE; EXO-1,4-BETA-D-XYLOSIDASE; FUNGAL PROTEIN; GLYCOCONJUGATE; LACTASE; MONOSACCHARIDE; PRODRUG; TAXOID; WATER; XYLAN 1,4 BETA XYLOSIDASE;

ARTICLE; BREAST TUMOR; CELL SURVIVAL; CHEMISTRY; DRUG EFFECT; FEMALE; GLYCOSYLATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HYDROLYSIS; METABOLISM; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PATHOLOGY; SOLUBILITY; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; BETA-GALACTOSIDASE; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL SURVIVAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; ESTERS; FEMALE; FUNGAL PROTEINS; GLYCOCONJUGATES; GLYCOSYLATION; HUMANS; HYDROLYSIS; LACTASE; MAGNETIC RESONANCE SPECTROSCOPY; MONOSACCHARIDES; PRODRUGS; SOLUBILITY; TAXOIDS; WATER; XYLOSIDASES;

EID: 80052258497     PISSN: None     EISSN: 14203049     Source Type: Journal    
DOI: 10.3390/molecules16086769     Document Type: Article

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