Molecular design, chemical synthesis, and biological evaluation of agents that selectively photo-degrade the transcription factor estrogen receptor-α

Organic and Biomolecular Chemistry

Volumn 9, Issue 18, 2011, Pages 6357-6366

  Tsumura, Kana ^a   Suzuki, Akane ^a   Tsuzuki, Takeo ^a   Tanimoto, Shuho ^a   Kaneko, Hajime ^a   Matsumura, Shuichi ^a   Imoto, Masaya ^a   Umezawa, Kazuo ^a   Takahashi, Daisuke ^a   Toshima, Kazunobu ^a  

^a KEIO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTAGONIST EFFECTS; BIOLOGICAL EVALUATION; CHEMICAL SYNTHESIS; ESTROGEN RECEPTOR; GLASS VESSEL; HIGH AFFINITY; INHIBITED GROWTH; LONG WAVELENGTH; MCF-7 BREAST CANCER CELLS; MCF-7 CELLS; MOLECULAR DESIGN; NEUTRAL CONDITIONS; PHOTO-IRRADIATION;

BIOSYNTHESIS; DEGRADATION; GROWTH KINETICS; TRANSCRIPTION; TRANSCRIPTION FACTORS;

IRRADIATION;

2 PHENYLQUINOLINE; 2-PHENYLQUINOLINE; 4-HYDROXYTAMOXIFEN; AFIMOXIFENE; ANTINEOPLASTIC AGENT; DRUG DERIVATIVE; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; QUINOLINE DERIVATIVE; TAMOXIFEN;

ARTICLE; BREAST TUMOR; CELL PROLIFERATION; CHEMISTRY; DRUG ANTAGONISM; DRUG EFFECT; DRUG POTENTIATION; FEMALE; HUMAN; METABOLISM; PHOTOLYSIS; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL PROLIFERATION; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; FEMALE; HUMANS; PHOTOLYSIS; QUINOLINES; TAMOXIFEN;

EID: 80052220136     PISSN: 14770520     EISSN: None     Source Type: Journal    
DOI: 10.1039/c1ob05629h     Document Type: Article

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