2-Phenylquinoline-carbohydrate hybrids: Molecular design, chemical synthesis, and evaluation of a new family of light-activatable DNA-cleaving agents

Angewandte Chemie - International Edition

Volumn 38, Issue 24, 1999, Pages 3733-3735

  Toshima, Kazunobu ^a   Takano, Ryusuke ^a   Maeda, Yutaka ^a   Suzuki, Masataka ^a   Asai, Akira ^b   Matsumura, Shuichi ^a  

^a KEIO UNIVERSITY   (Japan)

^b KYOWA HAKKO KOGYO CO LTD   (Japan)

Author keywords

Antitumor agents; Carbohydrates; Cytotoxicity; DNA cleavage

Indexed keywords

2 PHENYLQUINOLINE DERIVATIVE; AMINOPYRIDINE DERIVATIVE; AMINOSUGAR; CARBOHYDRATE DERIVATIVE; DICYCLOHEXYLCARBODIIMIDE; DNA; ETHYLENE GLYCOL; INTERCALATING AGENT; N BROMOSUCCINIMIDE;

ARTICLE; CONTROLLED STUDY; DNA CLEAVAGE; DRUG CYTOTOXICITY; DRUG DESIGN; DRUG SYNTHESIS; HELA CELL; HUMAN; HUMAN CELL; HYBRID; PHOTOACTIVATION; PHOTOCHEMISTRY; ULTRAVIOLET RADIATION;

EID: 0033576563     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1521-3773(19991216)38:24<3733::AID-ANIE3733>3.0.CO;2-W     Document Type: Article

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