Management of nonvariceal upper gastrointestinal bleeding

Journal of Postgraduate Medicine

Volumn 57, Issue 2, 2011, Pages 161-167

  Wee, E ^a  

^a KHOO TECK PUAT HOSPITAL   (Singapore)

Author keywords

Endoscopy; GI bleeding; management; proton pump inhibitor; review; upper gastrointestinal bleeding

Indexed keywords

ADRENALIN; ANTICOAGULANT AGENT; ERYTHROMYCIN; ESOMEPRAZOLE; FRESH FROZEN PLASMA; HEMOGLOBIN; HEMOSTATIC AGENT; HISTAMINE H2 RECEPTOR ANTAGONIST; METOCLOPRAMIDE; OMEPRAZOLE; OXYGEN; PANTOPRAZOLE; PLASMA SUBSTITUTE; PROKINETIC AGENT; PROTON PUMP INHIBITOR; RANITIDINE; UREA; VITAMIN K GROUP; WARFARIN;

ARGON PLASMA COAGULATION; BLOOD CLOT; BLOOD CLOTTING DISORDER; CLINICAL ASSESSMENT; COMORBIDITY; CONGESTIVE HEART FAILURE; CORONARY STENT; DIGESTIVE SYSTEM CANCER; DRUG ELUTING STENT; DRUG HYPERSENSITIVITY; ELECTROCOAGULATION; ENDOSCOPIC CLIPPING; ENDOSCOPIC THERAPY; ENDOSCOPY; EROSIVE GASTRITIS; ERYTHROCYTE CONCENTRATE; ESOPHAGITIS; GASTROINTESTINAL HEMORRHAGE; GLASGOW BLATCHFORD SCORE; HEALTH CARE COST; HEART DISEASE; HEART TAMPONADE; HEART VENTRICLE ARRHYTHMIA; HEMATEMESIS; HEMODYNAMICS; HEMOSTASIS; HOSPITALIZATION; HUMAN; HYPOTENSION; HYPOVOLEMIC SHOCK; INCIDENCE; INFUSION; INJECTION; INTERNATIONAL NORMALIZED RATIO; INTUBATION; ISCHEMIC HEART DISEASE; KIDNEY FAILURE; LASER COAGULATION; LIVER DISEASE; LIVER FAILURE; LOADING DRUG DOSE; LONG QT SYNDROME; MALLORY WEISS SYNDROME; MELENA; METASTASIS; MORTALITY; NAMED INVENTORIES, QUESTIONNAIRES AND RATING SCALES; NONVARICEAL UPPER GASTROINTESTINAL BLEEDING; OCCLUSIVE CEREBROVASCULAR DISEASE; OXYGEN MASK; OXYGEN THERAPY; PATIENT CARE; PEPTIC ULCER; PROGNOSIS; PROPHYLAXIS; RANDOMIZED CONTROLLED TRIAL (TOPIC); RESPIRATORY DISTRESS; RESUSCITATION; REVIEW; RISK ASSESSMENT; RISK BENEFIT ANALYSIS; RISK REDUCTION; SHOCK; STOMACH PH; SYNCOPE; SYSTOLIC BLOOD PRESSURE; TACHYCARDIA; THERAPY; THROMBOCYTE TRANSFUSION; TRANSFUSION; TREATMENT CONTRAINDICATION; TREATMENT FAILURE; UREA NITROGEN BLOOD LEVEL; VASOCONSTRICTION;

ESOPHAGEAL DISEASES; GASTROINTESTINAL HEMORRHAGE; HUMANS; RISK ASSESSMENT; SEVERITY OF ILLNESS INDEX; STOMACH DISEASES;

EID: 80052213126     PISSN: 00223859     EISSN: 09722823     Source Type: Journal    
DOI: 10.4103/0022-3859.81868     Document Type: Review

References (56)

1. Barkun A, Sabbah S, Enns R, Armstrong D, Gregor J, Fedorak RN, et al. The Canadian Registry on Nonvariceal Upper Gastrointestinal Bleeding and Endoscopy (RUGBE): Endoscopic hemostasis and proton pump inhibition are associated with improved outcomes in a real-life setting. Am J Gastroenterol 2004;99:1238-46. (Pubitemid 39062258)
2. Anand CS, Tandon BN, Nundy S. The causes, management and outcome of upper gastrointestinal haemorrhage in an Indian hospital. Br J Surg 1983;70:209-11. (Pubitemid 13161614)
3. Morgan AG, Clamp SE. O.M.G.E. International Upper Gastro-intestinal Bleeding Survey 1978-1982. Scand J Gastroenterol 1984;95:41-58. (Pubitemid 14117463)
4. Kumar A, Mishra SR, Sharma P, Sharma BC, Sarin SK. Clinical, laboratory, and hemodynamic parameters in portal hypertensive gastropathy: A study of 254 cirrhotics. J Clin Gastroenterol 2010;44:294-300.
5. Rana SS, Bhasin DK, Gupta R, Yadav TD, Gupta V, Singh K. Periampullary Dieulafoy's lesion: An unusual cause of gastrointestinal bleeding. JOP 2010;11:266-9.
6. Abraham P, Mukerji SS, Desai DC, Joshi AG. Dieulafoy lesion in mid-esophagus with esophageal varices. Indian J Gastroenterol 2004;23:220-1. (Pubitemid 40095969)
7. Shah AK, Banerjee D, Gambhir RP, Chaudhry R. Mallory-Weiss tear: Use of recombinant factor VIIa for exsanguinating bleed. Trop Gastroenterol 2009;30:226-7.
8. Vimalraj V, Kannan DG, Sukumar R, Rajendran S, Jeswanth S, Jyotibasu D, et al. Haemosuccus pancreaticus: Diagnostic and therapeutic challenges. HPB (Oxford) 2009;11:345-50.
9. Moses V, Keshava SN, Wann VC, Joseph P, Sitaram V. Cystic artery pseudoaneurysm after laparoscopic cholecystectomy presenting as haemobilia: A case report. Trop Gastroenterol 2008;29:107-9.
10. Ray G, Banerjee PK, Ghoshal UC, Dhar K, Pal BB, Biswas AD, et al. Etiology and management of obscure gastrointestinal bleed-an appraisal from eastern India. Indian J Gastroenterol 2001;20:90-3.
11. Thomson VS, Gopinath KG, Joseph E, Joseph G. Primary aorto-enteric fistula: A rare complication of abdominal aortic aneurysm. J Postgrad Med 2009;55:267-9.
12. Lim CH, Vani D, Shah SG, Everett SM, Rembacken BJ. The outcome of suspected upper gastrointestinal bleeding with 24-hour access to upper gastrointestinal endoscopy: A prospective cohort study. Endoscopy 2006;38:581-5. (Pubitemid 43978525)
13. Loperfido S, Baldo V, Piovesana E, Bellina L, Rossi K, Groppo M, et al. Changing trends in acute upper-GI bleeding: A population-based study. Gastrointest Endosc 2009;70:212-24.
14. Van Leerdam ME. Epidemiology of acute upper gastrointestinal bleeding. Best Pract Res Clin Gastroenterol 2008;22:209-24.
15. Singhal D, Kakodkar R, Nundy S. Management protocol for acute gastrointestinal bleeding. J Indian Med Assoc 2006;104:226-30.
16. Laine L, Peterson WL. Bleeding peptic ulcer. N Engl J Med 1994;331:717-27. (Pubitemid 24275746)
17. Somri M, Gaitini L, Yanovski B, Tome R, Resnikov I, Karsh K, et al. Flexible upper videoendoscopy through a modified endoscopy mask in infants and young children. J Pediatr Gastroenterol Nutr 2009;49:191-5.
18. Jairath V, Hearnshaw S, Brunskill SJ, Doree C, Hopewell S, Hyde C, et al. Red cell transfusion for the management of upper gastrointestinal haemorrhage. Cochrane Database Syst Rev 2010;8:006613.
19. Bonow RO, Carabello BA, Chatterjee K, de Leon AC Jr, Faxon DP, Freed MD, et al. American College of Cardiology/American Heart Association Task Force on Practice Guidelines. J Am J Coll Cardiol 2008;52:1-142.
20. Barkun AN, Bardou M, Kuipers EJ, Sung J, Hunt RH, Martel M, et al. International Consensus Upper Gastrointestinal Bleeding Conference Group. International consensus recommendations on the management of patients with nonvariceal upper gastrointestinal bleeding. Ann Intern Med 2010;152:101-13.
21. Anderson MA, Ben-Menachem T, Gan SI, Appalaneni V, Banerjee S, Cash BD, et al. Management of antithrombotic agents for endoscopic procedures. Gastrointest Endosc 2009;70:1060-70.
22. Blatchford O, Murray WR, Blatchford M. A risk score to predict need for treatment for upper-gastrointestinal haemorrhage. Lancet 2000;356:1318-21.
23. Rockall TA, Logan RF, Devlin HB, Northfield TC. Risk assessment after acute upper gastrointestinal haemorrhage. Gut 1996;38:316-21. (Pubitemid 26074312)
24. Vreeburg EM, Terwee CB, Snel P, Rauws EA, Bartelsman JF, Meulen JH, et al. Validation of the Rockall risk scoring system in upper gastrointestinal bleeding. Gut 1999;44:331-5. (Pubitemid 29119326)
25. Kim BJ, Park MK, Kim SJ, Kim ER, Min BH, Son HJ, et al. Comparison of scoring systems for the prediction of outcomes in patients with nonvariceal upper gastrointestinal bleeding: A prospective study. Dig Dis Sci 2009;54:2523-9.
26. Soncini M, Triossi O, Leo P, Magni G, Bertelé AM, Grasso T, et al. Management of patients with nonvariceal upper gastrointestinal hemorrhage before and after the adoption of the Rockall score, in the Italian Gastroenterology Units. Eur J Gastroenterol Hepatol 2007;19:543-7. (Pubitemid 46897296)
27. Stanley AJ, Ashley D, Dalton HR, Mowat C, Gaya DR, Thompson E, et al. Outpatient management of patients with low-risk uppergastrointestinal haemorrhage: Multicentre validation and prospective evaluation. Lancet 2009;373:42-7.
28. Ghassemi KA, Kovacs TO, Jensen DM. Gastric acid inhibition in the treatment of peptic ulcer hemorrhage. Curr Gastroenterol Rep 2009;11:462-9.
29. Patchett SE, Enright H, Afdhal N, O'Connell W, O'Donoghue DP. Clotlysis by gastric juice: An in vitro study. Gut 1989;30:1704-7. (Pubitemid 20061257)
30. Geus WP. Are there indications for intravenous acid-inhibition in the prevention and treatment of upper GI bleeding? Scand J Gastroenterol suppl 2000;232:10-20. (Pubitemid 32142732)
31. Lau JY, Leung WK, Wu JC, Chan FK, Wong VW, Chiu PW, et al. Omeprazole before endoscopy in patients with gastrointestinal bleeding. N Engl J Med 2007;356:1631-40. (Pubitemid 46631672)
32. Sreedharan A, Martin J, Leontiadis GI, Dorward S, Howden CW, Forman D, et al. Proton pump inhibitor treatment initiated prior to endoscopic diagnosis in upper gastrointestinal bleeding. Cochrane Database Syst Rev 2010;7:005415.
33. Dorward S, Sreedharan A, Leontiadis GI, Howden CW, Moayyedi P, Forman D. Proton pump inhibitor treatment initiated prior to endoscopic diagnosis in upper gastrointestinal bleeding. Cochrane Database Syst Rev 2006;4:005415.
34. Forrest JA, Finlayson ND, Shearman DJ. Endoscopy in gastrointestinal bleeding. Lancet 1974;2:394-7.
35. Lau JY, Chung SC, Leung JW, Lo KK, Yung MY, Li AK. The evolution of stigmata of hemorrhage in bleeding peptic ulcers: A sequential endoscopic study. Endoscopy 1998;30:513-8. (Pubitemid 28409967)
36. Hsu PI, Lin XZ, Chan SH, Lin CY, Chang TT, Shin JS, et al. Bleeding peptic ulcer-risk factors for rebleeding and sequential changes in endoscopic findings. Gut 1994;35:746-9.
37. Lau JY, Sung JJ, Lee KK, Yung MY, Wong SK, Wu JC, et al. Effect of intravenous omeprazole on recurrent bleeding after endoscopic treatment of bleeding peptic ulcers. N Engl J Med 2000;343:310-6. (Pubitemid 30616696)
38. Huggins RM, Scates AC, Latour JK. Intravenous proton-pump inhibitors versus H2-antagonists for treatment of GI bleeding. Ann Pharmacother 2003;37:433-7. (Pubitemid 36249647)
39. Hsu PI, Lo GH, Lo CC, Lin CK, Chan HH, Wu CJ, et al. Intravenous pantoprazole versus ranitidine for prevention of rebleeding after endoscopic hemostasis of bleeding peptic ulcers. World J Gastroenterol 2004;10:3666-9.
40. Van Rensburg C, Barkun AN, Racz I, Fedorak R, Bornman PC, Beglinger C, et al. Clinical trail: Intravenous pantoprazole vs. ranitidine for the prevention of peptic ulcer rebleeding: A multicentre, multinational, randomized trial. Aliment Pharmacol Ther 2009;29:497-507.
41. Alan N. Barkun, Marc Bardou, Ian M. Gralnek. Erythromycin and other prokinetics in acute upper gastrointestinal bleeding? A meta-analysis. Gastroenterology 2009;136;A-636.
42. Spiegel BM, Vakil NB, Ofman JJ. Endoscopy for acute nonvariceal upper gastrointestinal tract hemorrhage: Is sooner better? A systematic review. Arch Intern Med 2001;161:1393-404. (Pubitemid 32681159)
43. Sung JJ, Chan FK, Lau JY, Yung MY, Leung WK, Wu JC, et al. The effect of endoscopic therapy in patients receiving omeprazole for bleeding ulcers with nonbleeding visible vessels or adherent clots: A randomized comparison. Ann Intern Med 2003;139:237-43.
44. Jensen DM, Kovacs TO, Jutabha R, Machicado GA, Gralnek IM, Savides TJ, et al. Randomized trial of medical or endoscopic therapy to prevent recurrent ulcer hemorrhage in patients with adherent clots. Gastroenterology 2002;123:407-13. (Pubitemid 34827184)
45. Laine L, McQuaid KR. Endoscopic therapy for bleeding ulcers: An evidence-based approach based on meta-analyses of randomized controlled trials. Clin Gastroenterol Hepatol 2009;7:33-47.
46. Vergara M, Calvet X, Gisbert JP. Epinephrine injection versus epinephrine injection and a second endoscopic method in high risk bleeding ulcers. Cochrane Database Syst Rev 2007;2:005584.
47. Farin G, Grund KE. Technology of argon plasma coagulation with particular regard to endoscopic applications. Endosc Surg Allied Technol 1994;2:71-7.
48. Malick KJ. Clinical applications of argon plasma coagulation in endoscopy. Gastroenterol Nurs 2006;29:386-91.
49. Johanns W, Luis W, Janssen J, Kahl S, Greiner L. Argon plasma coagulation (APC) in gastroenterology: Experimental and clinical experiences. Eur J Gastroenterol Hepatol 1997;9:581-7. (Pubitemid 27267689)
50. Petersen BT, Hussain N, Marine JE, Trohman RG, Carpenter S, Chuttani R, et al. Endoscopy in patients with implanted electronic devices. Gastrointest Endosc 2007;65:561-8. (Pubitemid 46442830)
51. Sung JJ, Tsoi KK, Lai LH, Wu JC, Lau JY. Endoscopic clipping versus injection and thermo-coagulation in the treatment of non-variceal upper gastrointestinal bleeding: A meta-analysis. Gut 2007;56:1364-73.
52. Imhof M, Ohmann C, Röher HD, Glutig H; DUESUC study group. Endoscopic versus operative treatment in high-risk ulcer bleeding patients- results of a randomised study. Langenbecks Arch Surg 2003;387:327-36. (Pubitemid 36187842)
53. Lau JY, Sung JJ, Lam YH, Chan AC, Ng EK, Lee DW, et al. Endoscopic retreatment compared with surgery in patients with recurrent bleeding after initial endoscopic control of bleeding ulcers. N Engl J Med 1999;340:751-6. (Pubitemid 29114293)
54. Sam K. Kim, Vinay Duddalwar. Failed endoscopic therapy and the interventional radiologist: Non-variceal upper gastrointestinal bleeding. Tech Gastrointest Endosc 2005;7:148-155.
55. Ljungdahl M, Eriksson LG, Nyman R, Gustavsson S. Arterial embolisation in management of massive bleeding from gastric and duodenal ulcers. Eur J Surg 2002;168:384-90. (Pubitemid 35347014)
56. Poultsides GA, Kim CJ, Orlando R 3rd, Peros G, Hallisey MJ, Vignati PV. Angiographic embolization for gastroduodenal hemorrhage: Safety, efficacy, and predictors of outcome. Arch Surg 2008; 143:457-61. (Pubitemid 351717437)