The high mannose-type glycan binding lectin actinohivin: Dimerization greatly improves anti-HIV activity

Journal of Antibiotics

Volumn 64, Issue 8, 2011, Pages 551-557

  Takahashi, Atsushi ^a   Inokoshi, Junji ^b   Hachiya, Atsuko ^c   Oka, Shinichi ^c   Omura, Satoshi ^b   Tanaka, Haruo ^a,d  

^a IWAKI MEISEI UNIVERSITY   (Japan)

^b KITASATO UNIVERSITY   (Japan)

^c NATIONAL CENTER FOR GLOBAL HEALTH AND MEDICINE   (Japan)

^d KIIM Pharmceutical Laboratories Inc   (Japan)

Author keywords

actinohivin; anti HIV; dimer; high mannose type glycan; mannose binding lectin

Indexed keywords

ACTINOHIVIN; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; DIMER; MANNOSE BINDING LECTIN; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; DIMERIZATION; DRUG ACTIVITY; ESCHERICHIA COLI; EXPRESSION VECTOR; HUMAN IMMUNODEFICIENCY VIRUS 1; MUTATIONAL ANALYSIS; NONHUMAN; PRIORITY JOURNAL;

AMINO ACID SEQUENCE; BACTERIAL PROTEINS; ESCHERICHIA COLI; GIANT CELLS; HELA CELLS; HIV ENVELOPE PROTEIN GP120; HIV FUSION INHIBITORS; HIV-1; HUMANS; LECTINS; MANNOSE; MICROBIAL SENSITIVITY TESTS; MOLECULAR SEQUENCE DATA; POLYSACCHARIDES; PROTEIN BINDING; PROTEIN MULTIMERIZATION; RECOMBINANT FUSION PROTEINS;

ESCHERICHIA COLI; HUMAN IMMUNODEFICIENCY VIRUS 1; TOBACCO ETCH VIRUS;

EID: 80052211556     PISSN: 00218820     EISSN: 18811469     Source Type: Journal    
DOI: 10.1038/ja.2011.51     Document Type: Article

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