Differences in the heritability of growth and growth velocity during infancy and associations with fto variants

Obesity

Volumn 19, Issue 9, 2011, Pages 1847-1854

  Choh, Audrey C ^a   Curran, Joanne E ^b   Odegaard, Andrew O ^c   Nahhas, Ramzi W ^a   Czerwinski, Stefan A ^a   Blangero, John ^b   Towne, Bradford ^a   Demerath, Ellen W ^c  

^a WRIGHT STATE UNIVERSITY   (United States)

^b SOUTHWEST FOUNDATION FOR BIOMEDICAL RESEARCH   (United States)

^c UNIVERSITY OF MINNESOTA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AGE DISTRIBUTION; ARTICLE; BODY HEIGHT; BODY MASS; BODY WEIGHT; CHILD; CHILD GROWTH; CONTROLLED STUDY; DEVELOPMENTAL GENE; DEVELOPMENTAL STAGE; FAMILY STUDY; FEMALE; FTO GENE; GENE FUNCTION; GENETIC ASSOCIATION; GENETIC TRAIT; GENETIC VARIABILITY; GROWTH RATE; HERITABILITY; HUMAN; INFANT; LONGITUDINAL STUDY; MALE;

BODY HEIGHT; BODY MASS INDEX; BODY WEIGHT; CHILD DEVELOPMENT; FEMALE; GENETIC ASSOCIATION STUDIES; HUMANS; INFANT, NEWBORN; LONGITUDINAL STUDIES; MALE; MODELS, GENETIC; OHIO; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTEINS; QUANTITATIVE TRAIT, HERITABLE;

EID: 80052152240     PISSN: 19307381     EISSN: 1930739X     Source Type: Journal    
DOI: 10.1038/oby.2011.175     Document Type: Article

References (40)

1. Bateson P, Barker D, Clutton-Brock T et al. Developmental plasticity and human health. Nature 2004;430:419-421. (Pubitemid 38987896)
2. Bouchard C. Childhood obesity: are genetic differences involved? Am J Clin Nutr 2009;89:1494S-1501S.
3. Frayling TM, Timpson NJ, Weedon MN et al. A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity. Science 2007;316:889-894. (Pubitemid 46764279)
4. Freathy RM, Mook-Kanamori DO, Sovio U et al.; Genetic Investigation of ANthropometric Traits (GIANT) Consortium; Meta-Analyses of Glucose and Insulin-related traits Consortium; Wellcome Trust Case Control Consortium; Early Growth Genetics (EGG) Consortium. Variants in ADCY5 and near CCNL1 are associated with fetal growth and birth weight. Nat Genet 2010;42:430-435.
5. Monteiro PO, Victora CG. Rapid growth in infancy and childhood and obesity in later life-a systematic review. Obes Rev 2005;6:143-154. (Pubitemid 40604423)
6. Demerath EW, Choh AC, Czerwinski SA et al. Genetic and environmental influences on infant weight and weight change: the Fels Longitudinal Study. Am J Hum Biol 2007;19:692-702. (Pubitemid 47455653)
7. Towne B, Guo S, Roche AF, Siervogel RM. Genetic analysis of patterns of growth in infant recumbent length. Hum Biol 1993;65:977-989.
8. Cai G, Cole SA, Haack K, Butte NF, Comuzzie AG. Bivariate linkage confirms genetic contribution to fetal origins of childhood growth and cardiovascular disease risk in Hispanic children. Hum Genet 2007;121:737-744. (Pubitemid 46916973)
9. Lunde A, Melve KK, Gjessing HK, Skjaerven R, Irgens LM. Genetic and environmental influences on birth weight, birth length, head circumference, and gestational age by use of population-based parent-offspring data. Am J Epidemiol 2007;165:734-741. (Pubitemid 46434610)
10. Guo SS, Chumlea WC, Roche AF, Siervogel RM. Age-and maturity-related changes in body composition during adolescence into adulthood: the Fels Longitudinal Study. Int J Obes Relat Metab Disord 1997;21:1167-1175. (Pubitemid 27511492)
11. Scuteri A, Sanna S, Chen WM et al. Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits. PLoS Genet 2007;3:e115.
12. Dina C, Meyre D, Gallina S et al. Variation in FTO contributes to childhood obesity and severe adult obesity. Nat Genet 2007;39:724-726. (Pubitemid 46848595)
13. López-Bermejo A, Petry CJ, Díaz M et al. The association between the FTO gene and fat mass in humans develops by the postnatal age of two weeks. J Clin Endocrinol Metab 2008;93:1501-1505. (Pubitemid 351519755)
14. Gemma C, Sookoian S, Alvariñas J et al. Maternal pregestational BMI is associated with methylation of the PPARGC1A promoter in newborns. Obesity (Silver Spring) 2009;17:1032-1039.
15. Loos RJ, Lindgren CM, Li S et al.; Prostate, Lung, Colorectal, and Ovarian (PLCO) Cancer Screening Trial; KORA; Nurses' Health Study; Diabetes Genetics Initiative; SardiNIA Study; Wellcome Trust Case Control Consortium; FUSION. Common variants near MC4R are associated with fat mass, weight and risk of obesity. Nat Genet 2008;40:768-775. (Pubitemid 351748863)
16. Zhao J, Bradfield JP, Li M et al. The role of obesity-associated loci identified in genome-wide association studies in the determination of pediatric BMI. Obesity (Silver Spring) 2009;17:2254-2257.
17. Hardy R, Wills AK, Wong A et al. Life course variations in the associations between FTO and MC4R gene variants and body size. Hum Mol Genet 2010;19:545-552.
18. Roche AF. Growth, Maturation, and Body Composition: the Fels Longitudinal Study, 1929-1991. Cambridge University Press: Cambridge; New York, NY, 1992, pp xiii, 282.
19. Little RJA, Rubin DB. Statistical Analysis with Missing Data. John Wiley and Sons: Hoboken, 2002.
20. van Dommelen P, de Gunst MC, van der Vaart AW, Boomsma DI. Genetic study of the height and weight process during infancy. Twin Res 2004;7:607-616. (Pubitemid 39643563)
21. Almasy L, Blangero J. Multipoint quantitative-trait linkage analysis in general pedigrees. Am J Hum Genet 1998;62:1198-1211. (Pubitemid 28199022)
22. Towne B, Siervogel RM, Blangero J. Effects of genotype-by-sex interaction on quantitative trait linkage analysis. Genet Epidemiol 1997;14:1053-1058. (Pubitemid 28027532)
23. Boerwinkle E, Chakraborty R, Sing CF. The use of measured genotype information in the analysis of quantitative phenotypes in man. I. Models and analytical methods. Ann Hum Genet 1986;50:181-194. (Pubitemid 16116788)
24. Abecasis GR, Cookson WO, Cardon LR. Pedigree tests of transmission disequilibrium. Eur J Hum Genet 2000;8:545-551. (Pubitemid 30447129)
25. Trasande L, Cronk C, Durkin M et al. Environment and obesity in the National Children's Study. Environ Health Perspect 2009;117:159-166.
26. Morley R. Can we generalise from findings in twins? Paediatr Perinat Epidemiol 2005;19 Suppl 1:54-59. (Pubitemid 40260783)
27. Wardle J, Carnell S, Haworth CM, Plomin R. Evidence for a strong genetic influence on childhood adiposity despite the force of the obesogenic environment. Am J Clin Nutr 2008;87:398-404. (Pubitemid 351226077)
28. Demerath EW, Li J, Sun SS et al. Fifty-year trends in serial body mass index during adolescence in girls: the Fels Longitudinal Study. Am J Clin Nutr 2004;80:441-446. (Pubitemid 41080020)
29. Beardsall K, Ong KK, Murphy N et al. Heritability of childhood weight gain from birth and risk markers for adult metabolic disease in prepubertal twins. J Clin Endocrinol Metab 2009;94:3708-3713.
30. Silventoinen K, Pietiläinen KH, Tynelius P et al. Genetic and environmental factors in relative weight from birth to age 18: the Swedish young male twins study. Int J Obes (Lond) 2007;31:615-621. (Pubitemid 46482361)
31. Waddington CH. Canalization of development and genetic assimilation of acquired characters. Nature 1959;183:1654-1655.
32. Opitz JM, Mendez HM, Hall JG. Growth analysis in clinical genetics. Prog Clin Biol Res 1985;200:33-63.
33. Stettler N, Stallings VA, Troxel AB et al. Weight gain in the first week of life and overweight in adulthood: a cohort study of European American subjects fed infant formula. Circulation 2005;111:1897-1903. (Pubitemid 40570209)
34. Singhal A, Fewtrell M, Cole TJ, Lucas A. Low nutrient intake and early growth for later insulin resistance in adolescents born preterm. Lancet 2003;361:1089-1097. (Pubitemid 36369562)
35. Fredriksson R, Hägglund M, Olszewski PK et al. The obesity gene, FTO, is of ancient origin, up-regulated during food deprivation and expressed in neurons of feeding-related nuclei of the brain. Endocrinology 2008;149:2062-2071. (Pubitemid 351574484)
36. Fischer J, Koch L, Emmerling C et al. Inactivation of the Fto gene protects from obesity. Nature 2009;458:894-898.
37. Wardle J, Carnell S, Haworth CM et al. Obesity associated genetic variation in FTO is associated with diminished satiety. J Clin Endocrinol Metab 2008;93:3640-3643.
38. Haworth CM, Carnell S, Meaburn EL et al. Increasing heritability of BMI and stronger associations with the FTO gene over childhood. Obesity (Silver Spring) 2008;16:2663-2668.
39. Sébert SP, Hyatt MA, Chan LL et al. Influence of prenatal nutrition and obesity on tissue specific fat mass and obesity-associated (FTO) gene expression. Reproduction 2010;139:265-274.
40. Regnault N, Botton J, Forhan A et al. Determinants of early ponderal and statural growth in full-term infants in the EDEN mother-child cohort study. Am J Clin Nutr 2010;92:594-602.