Calcium-sensing receptors induce apoptosis during simulated ischaemia-reperfusion in Buffalo rat liver cells

Clinical and Experimental Pharmacology and Physiology

Volumn 38, Issue 9, 2011, Pages 605-612

  Xing, Wen Jing ^a   Kong, Fan Juan ^a   Li, Guang Wei ^a,d   Qiao, Kun ^e   Zhang, Wei Hua ^a   Zhang, Li ^a   Bai, Shu Zhi ^a   Xi, Yu Hui ^a   Li, Hong Xia ^a   Tian, Ye ^a   Ren, Huan ^a   Wu, Ling Yun ^a,c   Wang, Rui ^a,c   Xu, Chang Qing ^a,b  

^a HARBIN MEDICAL UNIVERSITY   (China)

^b Bio pharmaceutical Key Laboratory of Heilongjiang Province   (China)

^c LAKEHEAD UNIVERSITY   (Canada)

^d QIQIHAR MEDICAL UNIVERSITY   (China)

^e TAISHAN MEDICAL UNIVERSITY   (China)

Author keywords

BRL cell; Calcium sensing receptor; Ischemia reperfusion injury; Signal transduction pathway

Indexed keywords

CALCIUM SENSING RECEPTOR; CASPASE 3; CYTOCHROME C; GADOLINIUM CHLORIDE; HOE 33342; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN BAX; PROTEIN BCL 2; SYNAPTOPHYSIN;

ANIMAL CELL; APOPTOSIS; ARTICLE; BUFFALO RAT; CALCIUM CELL LEVEL; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; CULTURE MEDIUM; DOWN REGULATION; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; FLOW CYTOMETRY; LIVER CELL; LIVER ISCHEMIA; NONHUMAN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; REPERFUSION INJURY; UPREGULATION; WESTERN BLOTTING;

ANIMALS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CALCIUM; CASPASE 3; CELLS, CULTURED; CYTOCHROMES C; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GTP-BINDING PROTEIN ALPHA SUBUNITS, GQ-G11; HEPATOCYTES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORIC MONOESTER HYDROLASES; RATS; RATS, INBRED BUF; RECEPTORS, CALCIUM-SENSING; REPERFUSION INJURY; SIGNAL TRANSDUCTION; TYPE C PHOSPHOLIPASES;

EID: 80052094616     PISSN: 03051870     EISSN: 14401681     Source Type: Journal    
DOI: 10.1111/j.1440-1681.2011.05559.x     Document Type: Article

References (44)

1. Brown EM, MacLeod RJ. Extracellular calcium sensing and extracellular calcium signaling. Physiol. Rev. 2001; 81: 239-97.
2. 2+)-sensing receptor from bovine parathyroid. Nature 1993; 366: 575-80.
3. Smajilovic S, Tfelt-Hansen J. Calcium acts as a first messenger through the calcium-sensing receptor in the cardiovascular system. Cardiovasc. Res. 2007; 75: 457-67.
4. Fellner SK, Parker L. Ionic strength and the polyvalent cation receptor of shark rectal gland and artery. J. Exp. Zool. 2004; 301: 235-9.
5. Tfelt-Hansen J, MacLeod RJ, Chattopadhyay N et al. Calcium-sensing receptor stimulates PTHrP release by pathways dependent on PKC, p38 MAPK, JNK, and ERK1/2 in H-500 cells. Am.J.Physiol. 2003; 285: E329-37.
6. Xing W, Li G, Xi Y et al. The functional expression of calcium-sensing receptors in BRL cells and related signal transduction pathway responsible for intracellular calcium elevation. Mol.Cell. Biochem. 2010; 343: 13-9.
7. Cutrn JC, Perrelli MG, Cavalieri B et al. Microvascular dysfunction induced by reperfusion injury and protective effect of ischemic preconditioning. Free Radic. Biol. Med. 2002; 33: 1200-8.
8. Que X, Debonera F, Xie J et al. Pattern of ischemia reperfusion injury in a mouse orthotopic liver transplant model. J. Surg. Res. 2004; 116: 262-8.
9. Katsuramaki T, Isobe M, Kimura H et al. Different changes of endothelin-1 after reperfusion in a warm ischemia/reperfusion and transplantation model in pig liver. Transplant. Proc. 2000; 32: 2276-8.
10. Peralta C, Serafin A, Fernandez-Zabalegui L et al. Liver ischemic preconditioning: a new strategy for the prevention of ischemia-reperfusion injury. Transplant. Proc. 2003; 35: 1800-2.
11. Romanque UP, Uribe MM, Videla LA. Molecular mechanisms in liver ischemic-reperfusion injury and ischemic preconditioning. Rev. Med. Chil 2005; 133: 469-76.
12. Nauta RJ, Tsimoyiannis E, Uribe M et al. The role of calcium ions and calcium channel entry blockers in experimental ischemia-reperfusion-induced liver injury. Ann. Surg. 1991; 213: 137-42.
13. Lu P, Liu F, Wang CY et al. Gender differences in hepatic ischemic reperfusion injury in rats are associated with endothelial cell nitric oxide synthase-derived nitric oxide. World J. Gastroenterol. 2005; 11: 3441-5.
14. Chun K, Zhang J, Biewer J et al. Microcirculatory failure determines lethal hepatocyte injury in ischemic/reperfused rat livers. Shock 1994; 1: 3-9.
15. Kim YH, Lee SM. Role of Kupffer cells in the vasoregulatory gene expression during hepatic ischemia/reperfusion. Arch. Pharm. Res. 2004; 27: 111-7.
16. Kupiec-Weglinski JW, Busuttil RW. Ischemia and reperfusion injury in liver transplantation. Transplant. Proc. 2005; 37: 1653-6.
17. Yamada K, Miwa T, Liu J et al. Critical protection from renal ischemia reperfusion injury by CD55 and CD59. J. Immunol. 2004; 172: 3869-75.
18. de Vries B, Walter SJ, Peutz-Kootstra CJ et al. The mannose-binding lectin-pathway is involved in complement activation in the course of renal ischemia-reperfusion injury. Am. J. Pathol. 2004; 165: 1677-88.
19. Guo J, Li HZ, Zhang WH et al. Increased expression of calcium-sensing receptors induced by ox-LDL amplifies apoptosis of cardiomyocytes during simulated ischaemia-reperfusion. Clin. Exp. Pharmacol. Physiol. 2010; 37: e128-35.
20. Sun J, Murphy E. Calcium-sensing receptor: a sensor and mediator of ischemic preconditioning in the heart. Am. J. Physiol. Heart Circ. Physiol. 2010; 299: H1309-17.
21. Yan L, Zhu TB, Wang LS et al. Inhibitory effect of hepatocyte growth factor on cardiomyocytes apoptosis is partly related to reduced calcium sensing receptor expression during a model of simulated ischemia/reperfusion. Mol. Biol. Rep. 2010; 38: 2695-701.
22. Jiang CM, Han LP, Li HZ et al. Calcium-sensing receptors induce apoptosis in cultured neonatal rat ventricular cardiomyocytes during simulated ischemia/reperfusion. Cell Biol. Int. 2008; 32: 792-800.
23. Borzecka H, Bojarska-Junak A, Sikora P et al. Apoptosis of peripheral blood lymphocytes T in nephrotic children. Ann. Univ. Mariae Curie Sklodowska Med. 2004; 59: 253-6.
24. Naqvi S, Samim M, Abdin M et al. Concentration-dependent toxicity of iron oxide nanoparticles mediated by increased oxidative stress. Int J Nanomedicine. 2010; 5: 983-9.
25. 2+ evoked by 15-HETE in pulmonary arterial myocytes. Eur. J. Pharmacol. 2008; 601: 16-22.
26. Mebratu Y, Tesfaigzi Y. How ERK1/2 activation controls cell proliferation and cell death: is subcellular localization the answer? Cell cycle 2009; 8: 1168-75.
27. Kohli V, Selzner M, Madden JF et al. Endothelial cell and hepatocyte deaths occur by apoptosis after ischemia-reperfusion injury in the rat liver. Transplantation 1999; 67: 1099-105.
28. Kon K, Ikejima K, Okumura K et al. Role of apoptosis in acetaminophen hepatotoxicity. J. Gastroenterol. Hepatol. 2007; 22 (Suppl. 1): S49-52.
29. Ji C. Dissection of endoplasmic reticulum stress signaling in alcoholic and non-alcoholic liver injury. J. Gastroenterol. Hepatol. 2008; 23 (Suppl. 1): S16-24.
30. Uchiyama T, Otani H, Okada T et al. Nitric oxide induces caspase-dependent apoptosis and necrosis in neonatal rat cardiomyocytes. J. Mol. Cell. Cardiol. 2002; 34: 1049-61.
31. Bagchi D, Wetscher GJ, Bagchi M et al. Interrelationship between cellular calcium homeostasis and free radical generation in myocardial reperfusion injury. Chem-biol Interact 1997; 104: 65-85.
32. Kim R, Emi M, Tanabe K. Role of mitochondria as the gardens of cell death. Cancer Chemother. Pharmacol. 2006; 57: 545-53.
33. Lemasters JJ, Qian T, He L et al. Role of mitochondrial inner membrane permeabilization in necrotic cell death, apoptosis, and autophagy. Antioxid. Redox Signal. 2002; 4: 769-81.
34. Tsujimoto Y, Croce CM. Analysis of the structure, transcripts, and protein products of bcl-2, the gene involved in human follicular lymphoma. Proc. Natl. Acad. Sci. USA 1986; 83(14): 5214-8.
35. Chen Z, Chua CC, Ho YS et al. Overexpression of Bcl-2 attenuates apoptosis and protects against myocardial I/R injury in transgenic mice. Am J Physiol Heart Circ Physiol 2001; 280: H2313-20.
36. Zhao ZQ, Vinten-Johansen J. Myocardial apoptosis and ischemic preconditioning. Cardiovasc. Res. 2002; 55: 438-55.
37. Hattori R, Hernandez TE, Zhu L et al. An essential role of the antioxidant gene Bcl-2 in myocardial adaptation to ischemia: an insight with antisense Bcl-2 therapy. Antioxid. Redox Signal. 2001; 3: 403-13.
38. Kifor O, MacLeod RJ, Diaz R et al. Regulation of MAP kinase by calcium-sensing receptor in bovine parathyroid and CaR-transfected HEK293 cells. Am. J. Physiol. Renal Physiol. 2001; 280: F291-302.
39. Deng X, Ruvolo P, Carr B et al. Survival function of ERK1/2 as IL-3-activated, staurosporine-resistant Bcl2 kinases. Proc. Natl. Acad. Sci. USA. 2000; 97: 1578-83.
40. Liu YQ, Mu ZQ, You S et al. Fas/FasL signaling allows extracelluar-signal regulated kinase to regulate cytochrome c release in oridonin-induced apoptotic U937 cells. Biol. Pharm. Bull. 2006; 29: 1873-9.
41. Lewis JS, Vijayanathan V, Thomas TJ et al. Activation of cyclin D1 by estradiol and spermine in MCF-7 breast cancer cells: a mechanism involving the p38 MAP kinase and phosphorylation of ATF-2. Oncol. Res. 2005; 15: 113-28.
42. Marderosian M, Sharma A, Funk AP et al. Tristetraprolin regulates cyclin D1 and c-Myc mRNA stability in response to rapamycin in an Akt-dependent manner via p38 MAPK signaling. Oncogene 2006; 25: 6277-90.
43. Shi Y, Sharma A, Wu H et al. Cyclin D1 and c-myc internal ribosome entry site (IRES)-dependent translation is regulated by AKT activity and enhanced by rapamycin through a p38 MAPK- and ERK-dependent pathway. J. Biol. Chem. 2005; 280: 10964-73.
44. Ghatan S, Larner S, Kinoshita Y et al. p38 MAP kinase mediates bax translocation in nitric oxide-induced apoptosis in neurons J. Cell Biol. 2000; 150: 335-47.