Up-regulation of cyclin D1 by JNK1/c-Jun is involved in tumorigenesis of human embryo lung fibroblast cells induced by a low concentration of arsenite

Toxicology Letters

Volumn 206, Issue 2, 2011, Pages 113-120

  Li, Yuan ^a,b   Shen, Lu ^a,b   Xu, Hui ^a,b   Pang, Ying ^a,b   Xu, Yuan ^a,b   Ling, Min ^a,b   Zhou, Jianwei ^b   Wang, Xinru ^b   Liu, Qizhan ^a,b  

^a NANJING MEDICAL UNIVERSITY   (China)

^b Nanjing Medical University   (China)

Author keywords

Arsenite; C Jun; Cell cycle; Cyclin D1; Jun N terminal kinase 1; Neoplastic transformation

Indexed keywords

ARSENIC TRIOXIDE; CYCLIN D1; MITOGEN ACTIVATED PROTEIN KINASE P38; RETINOBLASTOMA PROTEIN; STRESS ACTIVATED PROTEIN KINASE 1;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CANCER SIZE; CARCINOGENESIS; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CELL PROLIFERATION; CELL TRANSFORMATION; CONTROLLED STUDY; EMBRYO; GENE EXPRESSION REGULATION; GENE REPRESSION; HUMAN; HUMAN CELL; LUNG CANCER; LUNG FIBROBLAST; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; UPREGULATION;

ANIMALS; ANTICARCINOGENIC AGENTS; ARSENITES; CARCINOGENS, ENVIRONMENTAL; CELL LINE; CELL PROLIFERATION; CELL TRANSFORMATION, NEOPLASTIC; CYCLIN D1; FIBROBLASTS; G1 PHASE; HUMANS; LUNG; LUNG NEOPLASMS; MICE; MICE, NUDE; MITOGEN-ACTIVATED PROTEIN KINASE 8; PROTEIN KINASE INHIBITORS; PROTO-ONCOGENE PROTEINS C-JUN; RNA INTERFERENCE; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; SODIUM COMPOUNDS; UP-REGULATION;

EID: 80052086584     PISSN: 03784274     EISSN: 18793169     Source Type: Journal    
DOI: 10.1016/j.toxlet.2011.06.024     Document Type: Article

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