Cyclin D1 is frequently overexpressed in microsatellite unstable colorectal cancer, independent of CpG island methylator phenotype

Histopathology

Volumn 53, Issue 5, 2008, Pages 588-598

  Nosho, K ^a   Kawasaki, T ^a   Chan, A T ^b,c   Ohnishi, M ^a   Suemoto, Y ^a   Kirkner, G J ^b   Fuchs, C S ^a,b   Ogino, S ^a,b,d  

^a HARVARD MEDICAL SCHOOL   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

^d HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

CCND1; CDKN1A; CIMP; Colon cancer; CpG island methylator phenotype; Cyclin; DNA methylation; Microsatellite instability; p21

Indexed keywords

CYCLIN D1; DNA;

ARTICLE; COLORECTAL CANCER; CONTROLLED STUDY; CPG ISLAND; DNA METHYLATION; GENE MUTATION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; PHENOTYPE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION;

AGED; COLORECTAL NEOPLASMS; CPG ISLANDS; CYCLIN D1; CYCLIN-DEPENDENT KINASE INHIBITOR P21; DNA METHYLATION; FEMALE; HUMANS; MALE; MICROSATELLITE INSTABILITY; MIDDLE AGED; MUTATION; PHENOTYPE; PROTO-ONCOGENE PROTEINS B-RAF; TISSUE ARRAY ANALYSIS;

EID: 54949096581     PISSN: 03090167     EISSN: 13652559     Source Type: Journal    
DOI: 10.1111/j.1365-2559.2008.03161.x     Document Type: Article

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