Effect of an acute mechanical stimulus on aortic structure in the transverse aortic constriction mouse model

Clinical and Experimental Pharmacology and Physiology

Volumn 38, Issue 9, 2011, Pages 570-576

  Chen, Jing ^a,b   Wu, Jian ^c   Li, Lei ^c   Zou, Yun Zeng ^c   Zhu, Ding Liang ^a,b,d   Gao, Ping Jin ^a,b,d  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b Chinese Academy of Sciences   (China)

^c FUDAN UNIVERSITY   (China)

^d Shanghai Institute of Hypertension   (China)

Author keywords

Adventitia; Aorta; Mechanical stimulus; Transverse aortic constriction

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; COLLAGEN; COLLAGEN TYPE 1; ELASTIN; EOSIN; HEMATOXYLIN; TRANSGELIN;

ADVENTITIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA; AORTA CONSTRICTION; ARTERY INTIMA; ARTERY MEDIA; ARTICLE; HEART CATHETER; HEMODYNAMICS; HISTOPATHOLOGY; HYPERPLASIA; IMMUNOHISTOCHEMISTRY; INFLAMMATORY INFILTRATE; MACROPHAGE; MALE; MECHANICAL STIMULATION; MOUSE; NONHUMAN; PROTEIN EXPRESSION; SHAM PROCEDURE; UPREGULATION;

ACTINS; ANIMALS; AORTA, THORACIC; AORTIC COARCTATION; BLOOD PRESSURE; COLLAGEN; FIBROBLASTS; FIBROSIS; HYPERTROPHY; MACROPHAGES; MALE; MICE; MICE, INBRED C57BL; MICROFILAMENT PROTEINS; MUSCLE PROTEINS; MUSCLE, SMOOTH, VASCULAR; STRESS, MECHANICAL; VENTRICULAR REMODELING;

EID: 80052082667     PISSN: 03051870     EISSN: 14401681     Source Type: Journal    
DOI: 10.1111/j.1440-1681.2011.05544.x     Document Type: Article

References (30)

1. Rockman HA, Ross RS, Harris AN et al. Segregation of atrial-specific and inducible expression of an atrial natriuretic factor transgene in an in vivo murine model of cardiac hypertrophy. Proc. Natl Acad. Sci. USA 1991; 88: 8277-81.
2. Beckles DL, Mascareno E, Siddiqui MA. Inhibition of Jak2 phosphorylation attenuates pressure overload cardiac hypertrophy. Vascul. Pharmacol. 2006; 45: 350-7.
3. Xia Y, Lee K, Li N et al. Characterization of the inflammatory and fibrotic response in a mouse model of cardiac pressure overload. Histochem. Cell Biol. 2009; 131: 471-81.
4. Song X, Kusakari Y, Xiao CY et al. mTOR attenuates the inflammatory response in cardiomyocytes and prevents cardiac dysfunction in pathological hypertrophy. Am. J. Physiol. Cell Physiol. 2010; 299: C1256-66.
5. Smeets PJ, Teunissen BE, Willemsen PH et al. Cardiac hypertrophy is enhanced in PPAR alpha-/- mice in response to chronic pressure overload. Cardiovasc. Res. 2008; 78: 79-89.
6. Eberth JF, Gresham VC, Reddy AK et al. Importance of pulsatility in hypertensive carotid artery growth and remodeling. J. Hypertens. 2009; 27: 2010-21.
7. Kwon JS, Lee SJ, Kim YG et al. Effect of pressure overload and its recovery on the rat carotid artery: Change of vascular reactivity and remodeling process. Heart Vessels 2006; 21: 48-55.
8. Li YH, Hsieh CY, Wang DL et al. Remodeling of carotid arteries is associated with increased expression of thrombomodulin in a mouse transverse aortic constriction model. Thromb. Haemost. 2007; 97: 658-64.
9. Li YH, Reddy AK, Ochoa LN et al. Effect of age on peripheral vascular response to transverse aortic banding in mice. J. Gerontol. A Biol. Sci. Med. Sci. 2003; 58: B895-9.
10. Langille BL. Arterial remodeling: Relation to hemodynamics. Can. J. Physiol. Pharmacol. 1996; 74: 834-41.
11. Davies PF. Flow-mediated endothelial mechanotransduction. Physiol. Rev. 1995; 75: 519-60.
12. Lemarie CA, Tharaux PL, Lehoux S. Extracellular matrix alterations in hypertensive vascular remodeling. J. Mol. Cell. Cardiol. 2010; 48: 433-9.
13. Rao RM, Yang L, Garcia-Cardena G, Luscinskas FW. Endothelial-dependent mechanisms of leukocyte recruitment to the vascular wall. Circ. Res. 2007; 101: 234-47.
14. Han WQ, Wu LY, Zhou HY et al. Changes in the composition of the thoracic aortic wall in spontaneously hypertensive rats treated with losartan or spironolactone. Clin. Exp. Pharmacol. Physiol. 2009; 36: 583-8.
15. Shi Y, O'Brien JE, Fard A et al. Adventitial myofibroblasts contribute to neointimal formation in injured porcine coronary arteries. Circulation 1996; 94: 1655-64.
16. Sartore S, Chiavegato A, Faggin E et al. Contribution of adventitial fibroblasts to neointima formation and vascular remodeling: From innocent bystander to active participant. Circ. Res. 2001; 89: 1111-21.
17. Maiellaro K, Taylor WR. The role of the adventitia in vascular inflammation. Cardiovasc. Res. 2007; 75: 640-8.
18. Nuki Y, Matsumoto MM, Tsang E et al. Roles of macrophages in flow-induced outward vascular remodeling. J. Cereb. Blood Flow Metab. 2009; 29: 495-503.
19. Mizutani K, Ikeda K, Kawai Y, Yamori Y. Biomechanical properties and chemical composition of the aorta in genetic hypertensive rats. J. Hypertens. 1999; 17: 481-7.
20. Chan V, Hoey A, Brown L. Improved cardiovascular function with aminoguanidine in DOCA-salt hypertensive rats. Br. J. Pharmacol. 2006; 148: 902-8.
21. Tang PC, Qin L, Zielonka J et al. MyD88-dependent, superoxide-initiated inflammation is necessary for flow-mediated inward remodeling of conduit arteries. J. Exp. Med. 2008; 205: 3159-71.
22. Kamiya A, Togawa T. Adaptive regulation of wall shear stress to flow change in the canine carotid artery. Am. J. Physiol. 1980; 239: H14-21.
23. Lehoux S, Tedgui A. Signal transduction of mechanical stresses in the vascular wall. Hypertension 1998; 32: 338-45.
24. Birukov KG. Cyclic stretch, reactive oxygen species, and vascular remodeling. Antioxid. Redox Signal. 2009; 11: 1651-67.
25. Li G, Chen SJ, Oparil S, Chen YF, Thompson JA. Direct in vivo evidence demonstrating neointimal migration of adventitial fibroblasts after balloon injury of rat carotid arteries. Circulation 2000; 101: 1362-5.
26. Siow RC, Mallawaarachchi CM, Weissberg PL. Migration of adventitial myofibroblasts following vascular balloon injury: Insights from in vivo gene transfer to rat carotid arteries. Cardiovasc. Res. 2003; 59: 212-21.
27. Laurent S, Boutouyrie P, Lacolley P. Structural and genetic bases of arterial stiffness. Hypertension 2005; 45: 1050-5.
28. Carnell PH, Vito RP, Taylor WR. Characterizing intramural stress and inflammation in hypertensive arterial bifurcations. Biomech. Model. Mechanobiol. 2007; 6: 409-21.
29. Capers Q, Alexander RW, Lou P et al. Monocyte chemoattractant protein-1 expression in aortic tissues of hypertensive rats. Hypertension 1997; 30: 1397-402.
30. Austyn JM, Gordon S. F4/80, a monoclonal antibody directed specifically against the mouse macrophage. Eur. J. Immunol. 1981; 11: 805-15.