Multimerization of adenovirus serotype 3 fiber knob domains is required for efficient binding of virus to desmoglein 2 and subsequent opening of epithelial junctions

Journal of Virology

Volumn 85, Issue 13, 2011, Pages 6390-6402

  Wang, Hongjie ^a,c   Li, Zong Yi ^a   Yumul, Roma ^a   Lara, Stephanie ^b   Hemminki, Akseli ^c   Fender, Pascal ^d   Lieber, André ^a,b  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

^c UNIVERSITY OF HELSINKI   (Finland)

^d EUROPEAN MOLECULAR BIOLOGY LABORATORY   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; DESMOGLEIN 2; EPIDERMAL GROWTH FACTOR RECEPTOR 2; FIBER KNOB PROTEIN; MEMBRANE PROTEIN; RECOMBINANT PROTEIN; TRASTUZUMAB; UNCLASSIFIED DRUG; VIRUS RECEPTOR; ADENOVIRUS RECEPTOR; CAPSID PROTEIN; HEXON CAPSID PROTEIN, ADENOVIRUS;

ADENOVIRUS; ADENOVIRUS 3; ARTICLE; BINDING AFFINITY; BREAST CANCER; CANCER CELL; CELL JUNCTION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; EPITHELIUM; EPITHELIUM CELL; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN POLYMERIZATION; PROTEIN PROTEIN INTERACTION; TIGHT JUNCTION; TRANSMISSION ELECTRON MICROSCOPY; VIRUS ATTACHMENT; VIRUS CELL INTERACTION; VIRUS PARTICLE; CELL LINE; CHEMISTRY; GENETIC TRANSDUCTION; GENETICS; HELA CELL; HUMAN ADENOVIRUS; METABOLISM; PATHOGENICITY; PHYSIOLOGY; PROTEIN BINDING; PROTEIN MULTIMERIZATION; PROTEIN TERTIARY STRUCTURE;

ADENOVIRIDAE;

ADENOVIRUSES, HUMAN; CAPSID PROTEINS; CELL LINE; DESMOGLEIN 2; EPITHELIAL CELLS; HELA CELLS; HUMANS; INTERCELLULAR JUNCTIONS; PROTEIN BINDING; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, VIRUS; RECOMBINANT PROTEINS; TRANSDUCTION, GENETIC;

EID: 80052051595     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.00514-11     Document Type: Article

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