Effects of hypoxia on epididymal sperm parameters and protective role of ibuprofen and melatonin

Biological Research

Volumn 44, Issue 2, 2011, Pages 161-167

  Vargas, Álvaro ^a   Bustos Obregón, Eduardo ^b   Hartley, Ricardo ^b  

^a UNIVERSIDAD SANTO TOMÁS   (Chile)

^b UNIVERSITY OF CHILE   (Chile)

Author keywords

Epididymal sperm; Ibuprofen; Melatonin; Mouse

Indexed keywords

ANTIOXIDANT; IBUPROFEN; MELATONIN; NONSTEROID ANTIINFLAMMATORY AGENT; REACTIVE OXYGEN METABOLITE;

ALTITUDE; ANIMAL; ANOXIA; ARTICLE; CYTOLOGY; DRUG EFFECT; EPIDIDYMIS; HEMATOCRIT; MALE; MOUSE; PATHOPHYSIOLOGY; PHYSIOLOGY; RETICULOCYTOSIS; SPERMATOZOON; SPERMATOZOON COUNT;

ALTITUDE; ANIMALS; ANOXIA; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ANTIOXIDANTS; EPIDIDYMIS; HEMATOCRIT; IBUPROFEN; MALE; MELATONIN; MICE; REACTIVE OXYGEN SPECIES; RETICULOCYTOSIS; SPERM COUNT; SPERMATOZOA;

ANIMALIA; MUS;

EID: 80052048218     PISSN: 07169760     EISSN: 07176287     Source Type: Journal    
DOI: 10.4067/S0716-97602011000200008     Document Type: Article

References (52)

1. AGARWAL A, SALEH RA, BEDAIWY MA. (2003) Role of reactive oxygen species in the pathophysiology of human reproduction. Fertil Steril. 79; 829-43.
2. AHOTUPA M, HUHTANIEMI I. (1992) Impaired detoxification of reactive oxygen and consequent oxidative stress in experimentally cryptorchid rat testis. Biol Reprod. 46;1114-1118.
3. AITKEN RJ, CLARKSON JS AND FISHEL C. (1989) Generation of reactive oxygen species, lipid peroxidauon and human sperm function Biol Reprod. 41;183-197.
4. BEALL CM. (2000) Tibetan and andean contrast in adaptation to highaltitude hypoxia. Adv Exp Med Biol. 475;63-74.
5. BERGER AM, HOBBS BB. (2006) Impact of shift work on the health and safety of nurses and patients. Clin J Oncol Nurs.10;465-71.
6. BHARDWAJ A, VERMA A, MAJUMDAR S, KHANDUJA L.(2000) Status of vitamin E and reduced glutathione in semen of oligozoospermic and azoospermic patients. Asian Journal Andrology. 2;225-228.
7. BISANTI L, OLSEN J, BASSO O, THONNEAU P, KARMAUS W. (1996) Shift work and sub fecundity: A European multicenter study. European Study Group Infertility and sub fecundity. J Occup Environ Med. 38;352-8.
8. BUSTOS-OBREGÓN E, CELIS R. (1982) Efecto de la hipoxia en la reproducción de mamíferos. Función testicular postexposición en cámara hipobárica. En el Hombre y los Ecosistemas de Montaña (MAB- 6), Montevideo: Ed. UNESCO-ROSTLAC. pp. 37-64.
9. BUSTOS-OBREGÓN E, ESVEILE C, CONTRERAS J, MAURER I, SARABIA L. (2006) Effects of chronic simulated hypobaric hypoxia on mouse spermatogenesis. Int. J. Morphol. 24;481-488
10. CHECK DB, GRAYSTONE JE, ROWE RD. (1969) Hipoxia and malnutrition in newborn rats: effects on RNA, DNA and protein in tissues. Am. J. Physiol. 217;642.
11. CIKUTOVIC M, FUENTES N, BUSTOS-OBREGÓN E. (2009) Effect of intermittent hypoxia on the reproduction of rats exposed to high altitude in the chilean altiplano. High Alt.Med.Biol.10;357-363.
12. CLERMONT Y. (1972) Kinetics of spermatogenesis in mammals: seminiferous epithelium cycle and spermatogonial renewal. Physiol Rev January.52;198-236.
13. COSTA G. (1996) The impact of shift and night work on health. Appl Ergon. 27;9-16.
14. CROGNIER E, VILLENA M, VARGAS E. (2002) Reproduction in high altitude Aymara: Physiological stress and fertility planning. J Biosoc Sci. 34;463-73.
15. DANG SN, YAN H, ZENG LX. (2006) Epidemiological features of spontaneous abortion among reproductive Tibetan woman living at high altitudes areas. Zhonghua Liu Xing Bing Xue Za Zhi. 27;212-6.
16. DONAYRE J. (1966) Population growth and fertility at high altitude. In life at high altitude, scientific publication No 140. Washington DC. Panamerican health organization. 74. In: Heat D, Williams DR. High altitude Medicine and Pathology, 1995. Oxford University Press Ed.
17. EL-MISSIRY M. (2000) Prophylactic effect of melatonin on lead-induced inhibition of heme biosynthesis and deterioration of antioxidants systems in male rats. J. Biochem. Mol. Tox. 14;57-62.
18. EL-SOKKARY GH, KAMEL ES, REITER RJ. (2003) Prophylactic effect of melatonin in reducing lead-induced neurotoxicity in the rat. Cellular and Molecular Biology Letters. 8; 461-470.
19. ERCAL N, TREERATPHAN P, HAMMOND TC, MATTHEWS RH, GRANNEMANN NH, SPITZ DR. (1996) In vivo indices of oxidative stress in lead-exposed c57bl/6 mice are reduced by treatment with meso-2,3-dimercaptosuccinic acid or N-acetylcysteine. Free Radicals Biology and Medicine. 21;157 -161.
20. FARÍAS JG, BUSTOS-OBREGÓN E, REYES JG. (2005) Increase in testicular temperature and vascularization induced by hypobaric hypoxia in rats. J. Androl. 26; 693-7.
21. FORNÉS M, BUSTOS-OBREGÓN E. (1994) Study of nuclear decondensation of the rat spermatozoa by reducing epididymal transit. Andrologia. 26;87-92.
22. FOUILLOT JO, BARRAULT D (1982). Fisiopatología y Altitud. Rev. Tribuna Médica LII 8); 9-17.
23. FRASER LR, QUINN PJ. (1981). A glycolytic product is obligatory for initiation of the sperm acrosome reaction and whiplash motility required for fertilization in the mouse. J Reprod Fertil. 61;25-35
24. GARRIDO N, MOSAEGUER M, SIMON C, PELLICER A. Y REMOHI J. (2004) Pro-oxidative and anti-oxidative imbalance in human semen and its relation with male fertility. Asian Journal Andrology. 6; 59 -65.
25. GASCO M, RUBIO J, CHUNG A, VILLEGAS L, GONZALES GF (2003). Effect of high altitude exposure on spermatogenesis and epididymal sperm count in male rats. Andrologia. 35;368-374
26. GONZALES GF, RODRÍGUEZ L, VALERA J, SANDOVAL E, GARCÍAHJARLES M. (1990). Prevention of high altitude-induced testicular disturbances by previous treatment with cyproheptadine in male rats. Arch Androl. 24;201-5.
27. GOLDEN AL, MOLINE JM, BAR-CHAMA N. (1999) Male reproduction and environmental and occupational exposures: a review of epidemiologic methods. Revista de Salud pública de México. 41;93-105.
28. HARMA M. (2006) Works hours in relation to work stress, recovery and health. Scand J Work Environ Health.32;502-14.
29. HENDIN BN, KOLETTIS PN, SHARMA RK, THOMAS AJ, AGARWAL A. (1999) Varicocele is associated with elevated spermatozoal reactive oxygen species production and diminished seminal plasma antioxidant capacity. J Urol.161;1831-1834.
30. HIRO-AKI Y, HAI-WANG T. (1996) Antagonistic effect of melatonin against cyanide-induced seizures and acute lethality in mice. Toxicology Letters. 87;19-24.
31. KIM JH, HAN S. (1969) Studies of hipoxia. V effects of anoxia on developing conective tisúes cells in rats. Anat. Rec. 165; 531.
32. KOGI K. (1996) Improving shift worker's health and tolerance to shift work: recent advances. Appl Ergon. 27;5-8.
33. KOKSAL IT, USTA M, ORHAN I, ABBASOGLU S, KADIOGLU A. (2003) Potential role of reactive oxygen species on testicular pathology associated with infertility. Asian Journal Andrology. 5;95-99.
34. LENA P, SUBRAMANIAN P. (2003) Evaluation of the antiperoxidative effects of melatonin in ammonium acetate-treated wistar rats. Polish Journal of Pharmacology. 55; 1031-1036.
35. LODISH H, BERK A, MATSUDAIRA P, KAISER C, KRIEGER M, SCOTT M, ZIPURSKY S, DARNEL L. (2005) In: Molecular biology of the cell. 5th Edition. Chapter 15: Respuestas de las células frente a infl uencias ambientales. 619-620.
36. MARTI H, KATSCHINSKI DM, WAGNER KF, SCHÄFFER L, STIER B. (2002) Isoform-Specific expression of Hypoxia-Inducible Factor-1 during the late stages of mouse spermiogenesis. Mol Endocrinol. 16;234-43.
37. MISRO MM, CHAKI SP, GAUTAM DK. (2005) Germ cell death and their removal during initial stages of testicular ischemia and cryptorchidism:a comparative analysis. Indian J Exp Biol.43;1080-1087.
38. MONK TH, FOLKARD S, WEDDERBURN A. (1996) Maintaining safety and high performance on shift work. Appl Ergon. 27;17-23.
39. MOORE LG, ARMAZA F, VILLENA M, VARGAS E. (2000) Comparative aspect of high-altitude adaptation in human populations. Adv Exp Med Biol. 475;45-62.
40. MOORE LG. (2003) Fetal growth restriction and maternal oxygen transport during high altitude pregnancy. High Alt Med Biol. 4;141-56.
41. MOUSTAFA MH, SHARMA RK, THORNTON J, MASCHA E, ABDELHAFEZ MA, THOMAS AJ. (2004) Relationship between ROS production, apoptosis and DNA denaturation in spermatozoa from patients examined for infertility. Hum Reprod. 19;129-38.
42. MURAD F. (2006) Nitric oxide and cyclic GMP in cell signaling and drug development. N Engl J Med. 355;2003-11
43. NIERMEYER S. (1999) The pregnant altitude visitor. Adv Exp Med Biol. 474;65-77.
44. NURMINEN T. (1998) Shift work and reproductive health. Scand J Work Environ Health. 24;28-34.
45. OKUMURA A, FUSE H, KAWAUCHI Y, MIZUNO I, AKASHI T. (2003) Changes in male reproductive function after high altitude mountaineering. High Alt Med Biol. 4; 349-53.
46. PANDE M, FLORA SJS. (2002) Lead induced oxidative damage and its response to combined administration of -lipoic acid and succimers in rats. Toxicology 177;187-196.
47. PELTOLA V, HUHTANIEMI I, AHOTUPA M. (1995) Abdominal position of the rat testis is associated with high level of lipid peroxidation. Biol Reprod. 53;1146-1150
48. SANJEEWANI T, PHILIP J, COLEMAN N. (2003) Ibuprofen-mediated reduction of Hypoxia-inducible factors HIF-1 and HIF-2 in Prostate Cancer Cells. Clinical Cancer Research. 9;3150-3157.
49. SANTORO G, ROMEO C. (2001) Normal and varicocele testis in adolescents. Asian J Androl. 3;259-262.
50. SCOTT AJ. (2000) Shift work and health. Prim Care. 27;1057-79.
51. SHEN HM, CHIA SE, ONG CN. (1999) Evaluation of oxidative DNA damage in human sperm and its association with male infertility. J Androl. 20;718-23.
52. SHEVANTAEVA ON, KOSYUGA YI. (2006) Effect of acute hypobaric hypoxia on spermatogenesis and lactate concentration in testicular tissue of male albino rats. Bull Exp Biol Med.141;20-2.