Numerical simulation of micro-particle deposition in a realistic human upper respiratory tract model during transient breathing cycle

Particuology

Volumn 9, Issue 4, 2011, Pages 424-431

  Huang, Jianhua ^a   Zhang, Lianzhong ^b,c  

^a Jiangsu Xuzhou Construction Machinery Research Institute   (China)

^b NANKAI UNIVERSITY   (China)

^c Chinese Academy of Sciences   (China)

Author keywords

Airflow pattern; Human upper respiratory tract; Micro particle deposition; Transient breathing cycle

Indexed keywords

AIRFLOW PATTERNS; BREATHING CYCLE; DEPOSITION FRACTIONS; DEPOSITION PATTERNS; EXPERIMENTAL DATA; HOT SPOT; INSPIRATORY FLOW; MASS DISTRIBUTION; MICRO-PARTICLE DEPOSITION; MOUTH CAVITY; OROPHARYNX; PARTICLE DEPOSITIONS; PARTICLE DIAMETERS; THEORETICAL MODELS; TRANSIENT AIRFLOW; TURBULENCE INTENSITY; UPPER RESPIRATORY TRACT;

COMPUTER SIMULATION; FLOW RATE; SECONDARY FLOW;

DEPOSITION;

EID: 80052037754     PISSN: 16742001     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.partic.2011.02.004     Document Type: Article

References (23)

1. I. Balashazy, W. Hofmann, and T.B. Martonen Inertial impaction and gravitational deposition of aerosols in curved tube and airway bifurcations Aerosol Science and Technology 13 1990 308 321 (Pubitemid 20312881)
2. F.S. Cai, and C.P. Yu Inertial and interceptional deposition of spherical particles and fibers in a bifurcating airway Journal of Aerosol Science 19 1988 679 688
3. T.L. Chan, and M. Lippmann Experimental measurements and empirical modeling of the regional deposition of inhaled particles in humans American Industrial Hygiene Association Journal 41 1980 399 409 (Pubitemid 10121154)
4. Y.S. Cheng, Y. Zhou, and B.T. Chen Particle deposition in a cast of human oral airways Aerosol Science and Technology 31 1999 286 300 (Pubitemid 32001437)
5. L.T. Choi, J.Y. Tu, H.F. Li, and F. Thien Flow and particle deposition patterns in a realistic human double bifurcation airway model Inhalation Toxicology 19 2007 117 131 (Pubitemid 46005621)
6. R. Clift, J.R. Grace, and M.E. Weber Bubbles, drops and particles 1978 Academic Press New York
7. A.F. Heenan, E. Matida, A. Pollard, and W.H. Finlay Experimental measurements and computational modeling of the flow field in an idealized human oropharynx Experiments in Fluids 35 2003 70 84 (Pubitemid 37005776)
8. J. Huang, and L. Zhang Effect of cartilaginous rings on particle deposition in human upper airway model. (in Chinese) China Powder Science and Technology 16 1 2010 85 88
9. J. Huang, and L. Zhang Micro-particle deposition and lobar distribution of mass flow in human upper respiratory tract model Chinese Science Bulletin 56 2011 380 385
10. J. Huang, L. Zhang, and S. Yu Modeling micro-particle deposition in human upper respiratory tract under steady inhalation Particuology 9 2011 39 43
11. Z. Li, C. Kleinstreuer, and Z. Zhang Simulation of airflow fields and microparticle deposition in realistic human lung airway models. Part I. Airflow patterns European Journal of Mechanics B/Fluids 26 5 2007 632 649 (Pubitemid 47048728)
12. Z. Li, C. Kleinstreuer, and Z. Zhang Simulation of airflow fields and microparticle deposition in realistic human lung airway models. Part II. Particle transport and deposition Deposition and European Journal of Mechanics B/Fluids 26 5 2007 650 668 (Pubitemid 47048729)
13. A. Moskal, and L. Gradon Temporary and spatial deposition of aerosol particles in the upper human airways during breathing cycle Journal of Aerosol Science 33 2002 1525 1539 (Pubitemid 35300481)
14. J. Sandeau, I. Katz, R. Fodil, B. Louis, G. Apiou-Sbirlea, and G. Caillibotte CFD simulation of particle deposition in a reconstructed human oral extrathoracic airway for air and helium-oxygen mixtures Journal of Aerosol Science 41 2010 281 294
15. R.B. Schlesinger, D.E. Bohning, T.L. Chan, and M. Lippmann Particle deposition in a hollow cast of human tracheobronchial tree Journal of Aerosol Science 8 1977 429 445 (Pubitemid 8566577)
16. D.C. Wilcox Turbulence modeling for CFD 1998 DCW Industries Inc. California
17. H.C. Yeh, and G.M. Schum Models of human lung airways and their application to inhaled particle deposition Bulletin of Mathematical Biology 42 1980 461 480 (Pubitemid 10092310)
18. Y. Zhang, and W.H. Finlay Measurement of the effect of cartilaginous rings on particle deposition in a proximal lung bifurcation model Aerosol Science and Technology 39 2005 394 399 (Pubitemid 40770115)
19. Z. Zhang, and C. Kleinstreuer Transient airflow structures and particle transport in a sequentially branching lung airway model Physics of Fluids 14 2002 862 880 (Pubitemid 34143782)
20. Z. Zhang, C. Kleinstreuer, and C.S. Kim Micro-particle transport and deposition in a human oral airway model Journal of Aerosol Science 33 2002 1635 1652 (Pubitemid 35375927)
21. Z. Zhang, C. Kleinstreuer, and C.S. Kim Comparison of analytical and CFD models with regard to micron particle deposition in a human 16-generation tracheobronchial airway model Journal of Aerosol Science 40 2009 16 28
22. Y. Zhou, and Y.S. Cheng Particle deposition in a cast of human tracheobronchial airways Aerosol Science and Technology 39 2005 492 500 (Pubitemid 40993227)
23. Y. Zhou, W.C. Su, and Y.S. Cheng Fiber deposition in the tracheobronchial region: Deposition equations Inhalation Toxicology 20 2008 1191 1198