Structural characteristics of a hyperbranched acidic polysaccharide from the stems of Ephedra sinica and its effect on T-cell subsets and their cytokines in DTH mice

Carbohydrate Polymers

Volumn 86, Issue 4, 2011, Pages 1705-1711

  Kuang, Haixue ^a   Xia, Yonggang ^a   Liang, Jun ^a   Yang, Bingyou ^a   Wang, Qiuhong ^a   Wang, Xinguo ^a  

^a HEILONGJIANG UNIVERSITY OF CHINESE MEDICINE   (China)

Author keywords

Delayed type hypersensitivity; Ephedra sinica Stapf; Immunosuppressive effects; Polysaccharides; Structural characteristics

Indexed keywords

ACID HYDROLYSIS; ACIDIC POLYSACCHARIDES; CYTOKINES; DELAYED TYPE HYPERSENSITIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; EPHEDRA SINICA; FLOW-CYTOMETRIC ANALYSIS; FT-IR SPECTRUM; GEL-FILTRATION CHROMATOGRAPHY; GLUCURONIC ACIDS; HYPERBRANCHED; IMMUNOSUPPRESSIVE DRUGS; IMMUNOSUPPRESSIVE EFFECTS; IN-VIVO; MECHANISM OF ACTION; METHYLATION ANALYSIS; PERIODATE OXIDATION; REPEATING UNIT; SMITH DEGRADATION; STRUCTURAL CHARACTERISTICS; T CELLS;

ALKYLATION; BODY FLUIDS; GEL PERMEATION CHROMATOGRAPHY; GLUCOSE; ION EXCHANGE; PHOTODEGRADATION;

MAMMALS;

EPHEDRA SINICA; MUS;

EID: 80052031272     PISSN: 01448617     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.carbpol.2011.07.001     Document Type: Article

References (30)

1. A.C. Allison Immunosuppressive drugs: The first 50 years and a glance forward Immunopharmacology 47 2000 63 83 (Pubitemid 30394533)
2. A. Bensadoun, and D. Weinstein Assay of proteins in presence of interfering materials Analytical Biochemistry 54 1976 484 489
3. R.M. Cheng, G.X. Zhu, and Z.Y. Xu Effect of different extracts from Ephedra on cell immunity Journal of Nanjing TCM University 17 2001 234 236
4. K.M. Comar, and D.F. Kirby Herbal remedies in gastroenterology Journal of Clinical Gastroenterology 39 2005 457 468 (Pubitemid 40863640)
5. S.W. Cui Food carbohydrates: Chemistry, physical properties, and applications 2005 CRC Press Taylor & Francis Group
6. L.L. Ding, R.S. Shi, J. Cui, S.C. Wang, and Z.T. Wang Advances in research of chemical constituents and pharmacological activities of Ephedra China Journal of Chinese Materia Medica 31 2006 1661 1664
7. Q. Dong, J. Yao, J.N. Fang, and K. Ding Structural characterization and immunological activity of two cold water extractable polysaccharides from Cistanche deserticola Y. C. Ma Carbohydrate Research 342 2007 1343 1349 (Pubitemid 46770652)
8. J.Y. Duan, V.L. Chen, Q. Dong, K. Ding, and J.N. Fang Chemical structure and immunoinhibitory activity of a pectic polysaccharide containing glucuronic acid from the leaves of Diospyros kaki International Journal of Biological Macromolecules 46 2010 465 470
9. K. Ghosh, K. Chandra, S.K. Roy, S. Mondal, D. Maiti, and D. Das Structural investigation of a polysaccharide (Fr. I) isolated from the aqueous extract of an edible mushroom, Volvariella diplasia Carbohydrate Research 343 2008 1071 1078
10. L. He, N. Yin, J.W. Cheng, X.Q. Wu, J.X. Jiang, and X.L. Song Structural features of a new heteropolysaccharide from the fruit bodies of Melia azedarach and its effect on cytotoxic activity Fitoterapia 80 2009 399 403
11. N. Hill, and N. Sarvetnick Cytokines: Promoters and dampeners of autoimmunity Current Opinion in Immunology 14 2002 791 797 (Pubitemid 35292428)
12. + T cells Journal of Ethnopharmacology 123 2009 6 14
13. K. Kobayashi, K. Kaneda, and T. Kasama Immunopathogenesis of delayed-type hypersensitivity Microscopy Research and Technique 53 2001 24 245
14. H.X. Kuang, Y.G. Xia, B.Y. Yang, Q.H. Wang, and Y.H. Wang Screening and comparison of the immunosuppressive activities of polysaccharides from the stems of Ephedra sinica Stapf Carbohydrate Polymers 83 2011 787 795
15. J.W. Li, L.P. Fan, and S.D. Ding Isolation, purification and structure of a new water-soluble polysaccharide from Zizyphus jujuba cv. Jinsixiaozao Carbohydrate Polymers 83 2011 477 482
16. S. Mondal, K. Chandra, D. Maiti, A.K. Ojha, D. Das, and S.K. Roy Chemical analysis of a new fucoglucan isolated from an edible mushroom, Termitomyces robustus Carbohydrate Research 343 2008 1062 1070
17. A.K. Ojha, D. Maiti, K. Chandra, S. Mondal, D.D.S.K. Roy, and K. Ghosh Structural assignment of a heteropolysaccharide isolated from the gum of Cochlospermum religiosum (Katira gum) Carbohydrate Research 343 2008 1222 1231
18. D.L. Qiao, J. Liu, C.L. Ke, Y. Sun, H. Ye, and X.X. Zeng Structural characterization of polysaccharides from Hyriopsis cumingii Carbohydrate Polymers 82 2010 1184 1190
19. E.B. Samoilova, J.L. Horton, B. Hilliard, T.S. Liu, and Y. Chen IL-6 deficient mice are resistant to experimental autoimmune encephalomyelitis: Roles of IL-6 in the activation and differentiation of autoreactive T cells The Journal of Immunology 161 1998 6480 6486 (Pubitemid 28562184)
20. L.W. Sun, K. Feng, R. Jiang, J.Q. Chen, Y. Zhao, and R. Ma Water-soluble polysaccharide from Bupleurum chinense DC: Isolation, structural features and antioxidant activity Carbohydrate Polymers 79 2010 180 183
21. H.B. Tong, Z.Y. Liang, and G.Y. Wang Structural characterization and hypoglycemic activity of a polysaccharide isolated from the fruit of Physalis alkekengi L Carbohydrate Polymers 71 2008 316 323
22. J.F. Viallard, J.L. Pellegrin, V. Ranchin, T. Schaeverbeke, J. Dehais, and M.L. Boursier Th1 (IL-2, interferon-gamma (IFN-γ)) and Th2 (IL-10, IL-4) cytokine production by peripheral blood mononuclear cells (PBMC) from patients with systemic lupus erythematosus (SLE) Clinical Experimental Immunology 115 1999 189 195 (Pubitemid 29030384)
23. C.R. Wu, X. Jiang, S.T. He, B. Yang, J.Z. Hu, and R. Cai Effects of QWBZP on T-cell subsets and their cytokines in intestinal mucosa of HRV infection suckling mice Journal of Ethnopharmacology 131 2010 130 134
24. Y.G. Xia, H.X. Kuang, B.Y. Yang, Q.H. Wang, J. Liang, and Y.P. Sun Optimum extraction of acidic polysaccharides from the stems of Ephedra sinica Stapf by Box-Behnken statistical design and its anti-complement activity Carbohydrate Polymers 84 2011 282 291
25. Y.G. Xia, J. Liang, B.Y. Yang, Q.H. Wang, and H.X. Kuang Identification of two cold water-soluble polysaccharides from the stems of Ephedra sinica Stapf Chinese Medicine 1 2010 63 68
26. Y.G. Xia, Q.H. Wang, J. Liang, B.Y. Yang, G.Y. Li, and H.X. Kuang Development and application of a rapid and efficient HPCE method coupled with correction factors for determination of monosaccharide composition of acidic hetero-polysaccharides from Ephedra sinica Phytochemical Analysis 22 2011 103 111
27. D.H. Yasui, T. Genetta, T. Kadesch, T.M. Williams, S.L. Swain, and L.V. Tsui Transcriptional repression of the IL-2 gene in Th cells by ZEB The Journal of Immunology 160 1998 4433 4440 (Pubitemid 28217301)
28. Y. Yin, F.Y. Gong, X.X. Wu, Y. Sun, Y.H. Li, and T. Chen Anti-inflammatory and immunosuppressive effect of flavones isolated from Artemisia vestita Journal of Ethnopharmacology 120 2008 1 6
29. J.W. Yoon, H.S. Jun, and P. Santamaria Cellular and molecular mechanisms for the initiation and progression of beta cell destruction resulting from the collaboration between macrophages and T cells Autoimmunity 27 1998 109 122 (Pubitemid 28154181)
30. M.Y. Zhu, J.G. Mo, C.S. He, H.P. Xie, N. Ma, and C.J. Wang Extraction, characterization of polysaccharides from lycium barbarum and its effect on bone gene expression in rats Carbohydrate Polymers 80 2010 672 676