Astrocyte activation but not neuronal impairment occurs in the hippocampus of mice after 2 weeks of d-galactose exposure

Life Sciences

Volumn 89, Issue 11-12, 2011, Pages 355-363

  Wu, Wei ^a   Li, Min ^a   Liu, Lei ^a   Gao, Junying ^a   Kong, Hui ^a   Ding, Jiong ^a   Hu, Gang ^a   Xiao, Ming ^a  

^a NANJING MEDICAL UNIVERSITY   (China)

Author keywords

Aquaporin 4; Astrocytes; d galactose; Glutamate transporter; Oxidative stress

Indexed keywords

AQUAPORIN 4; BETA TUBULIN; GALACTOSE; SYNAPTOPHYSIN; VESICULAR GLUTAMATE TRANSPORTER 1;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BRAIN HOMOGENATE; CONTROLLED STUDY; DENDRITE; ELECTRON MICROSCOPY; EXPOSURE; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; MALE; MOUSE; NERVE CELL NECROSIS; NERVE DEGENERATION; NONHUMAN; OXIDATION; STRATUM RADIATUM; SWELLING; SYNAPSE; ULTRASTRUCTURE;

ANIMALS; ANTIOXIDANTS; ASTROCYTES; BRAIN; CELL DEATH; GALACTOSE; GLUTAMIC ACID; HIPPOCAMPUS; MALE; MICE; MICE, INBRED ICR; NEURODEGENERATIVE DISEASES; NEURONS; OXIDATIVE STRESS;

MUS;

EID: 80052030472     PISSN: 00243205     EISSN: 18790631     Source Type: Journal    
DOI: 10.1016/j.lfs.2011.06.028     Document Type: Article

References (34)

1. N.J. Allen, and B.A. Barres Neuroscience: Glia-more than just brain glue Nature 457 2009 675 677
2. S.N. Burke, and C.A. Barnes Neural plasticity in the ageing brain Nat Rev Neurosci 7 2006 30 40 (Pubitemid 41828929)
3. P.H. Chan, L. Chu, and S. Chen Effects of MK-801 on glutamate-induced swelling of astrocytes in primary cell culture J Neurosci Res 25 1990 87 93 (Pubitemid 20051032)
4. J.T. Coyle, and P. Puttfarcken Oxidative stress, glutamate, and neurodegenerative disorders Science 262 1993 689 695 (Pubitemid 23350687)
5. X. Cui, P. Zuo, Q. Zhang, X. Li, Y. Hu, and J. Long Chronic systemic d-galactose exposure induces memory loss, neurodegeneration, and oxidative damage in mice: protective effects of R-alpha-lipoic acid J Neurosci Res 84 2006 647 654 (Pubitemid 44196705)
6. R. Dringen, and J. Hirrlinger Glutathione pathways in the brain Biol Chem 384 2003 505 516 (Pubitemid 36609167)
7. C. Escartin, and G. Bonvento Targeted activation of astrocytes: a potential neuroprotective strategy Mol Neurobiol 38 2008 231 241
8. S. Fuller, G. Münch, and M. Steele Activated astrocytes: a therapeutic target in Alzheimer's disease? Expert Rev Neurother 9 2009 1585 1594
9. E. Gunnarson, M. Zelenina, G. Axehult, Y. Song, A. Bondar, and P. Krieger Identification of a molecular target for glutamate regulation of astrocyte water permeability Glia 56 2008 587 596
10. B.C. Han, S.B. Koh, E.Y. Lee, and Y.H. Seong Regional difference of glutamate-induced swelling in cultured rat brain astrocytes Life Sci 76 2004 573 583 (Pubitemid 39535668)
11. S.R. Hinson, S.F. Roemer, C.F. Lucchinetti, J.P. Fryer, T.J. Kryzer, and J.L. Chamberlain Aquaporin-4-binding autoantibodies in patients with neuromyelitis optica impair glutamate transport by down-regulating EAAT2 J Exp Med 205 2008 2473 2481
12. S.C. Ho, J.H. Liu, and R.Y. Wu Establishment of the mimetic aging effect in mice caused by d-galactose Biogerontology 4 2003 15 18
13. H.M. Hsieh, W.M. Wu, and M.L. Hu Soy isoflavones attenuate oxidative stress and improve parameters related to aging and Alzheimer's disease in C57BL/6J mice treated with d-galactose Food Chem Toxicol 47 2009 625 632
14. X. Hua, M. Lei, Y. Zhang, J. Ding, Q. Han, and G. Hu Long-term d-galactose injection combined with ovariectomy serves as a new rodent model for Alzheimer's disease Life Sci 80 2007 1897 1905 (Pubitemid 46560732)
15. Y. Ishikawa, T. Satoh, Y. Enokido, C. Nishio, T. Ikeuchi, and H. Hatanaka Generation of reactive oxygen species, release of l-glutamate and activation of caspases are required for oxygen-induced apoptosis of embryonic hippocampal neurons in culture Brain Res 824 1999 71 80 (Pubitemid 29222887)
16. Y. Koyama, T. Sugimoto, Y. Shigenaga, A. Baba, and H. Iwata A morphological study on glutamate-induced swelling of cultured astrocytes: involvement of calcium and chloride ion mechanisms Neurosci Lett 124 1991 235 238
17. K.P. Lehre, L. Levy, O.P. Ottersen, J. Storm-Mathisen, and N.C. Danbolt Differential expression of two glial glutamate transporters in the rat brain: quantitative and immunocytochemical observations J Neurosci 15 1995 1835 1853
18. M. Lei, X. Hua, M. Xiao, J. Ding, Q. Han, and G. Hu Impairments of astrocytes are involved in the d-galactose-induced brain aging Biochem Biophys Res Commun 369 2008 1082 1087
19. M. Lei, Y. Su, X. Hua, J. Ding, Q. Han, and G. Hu Chronic systemic injection of d-galactose impairs the septohippocampal cholinergic system in rats Neuroreport 19 2008 1611 1615
20. H. Liu, H. Wang, S. Shenvi, T.M. Hagen, and R.M. Liu Glutathione metabolism during aging and in Alzheimer disease Ann N Y Acad Sci 1019 2004 346 349 (Pubitemid 38951332)
21. L. Liu, Y. Su, W. Yang, M. Xiao, J. Gao, and G. Hu Disruption of neuronal-glial-vascular units in the hippocampus of ovariectomized mice injected with d-galactose Neuroscience 169 2010 596 608
22. J. Lu, Y.L. Zheng, D.M. Wu, L. Luo, D.X. Sun, and Q. Shan Ursolic acid ameliorates cognition deficits and attenuates oxidative damage in the brain of senescent mice induced by d-galactose Biochem Pharmacol 74 2007 1078 1090 (Pubitemid 47284011)
23. J. Lu, D.M. Wu, B. Hu, W. Cheng, Y.L. Zheng, and Z.F. Zhang Chronic administration of troxerutin protects mouse brain against d-galactose-induced impairment of cholinergic system Neurobiol Learn Mem 93 2009 157 164
24. N.J. Maragakis, and J.D. Rothstein Mechanisms of Disease: astrocytes in neurodegenerative disease Nat Clin Pract Neurol 2 2006 679 689 (Pubitemid 44782682)
25. D.E. Pellegrini-Giampietro, G. Cherici, M. Alesiani, V. Carla, and F. Moroni Excitatory amino acid release from rat hippocampal slices as a consequence of free-radical formation J Neurochem 51 1988 1960 1963 (Pubitemid 19010993)
26. A. Reynolds, C. Laurie, R.L. Mosley, and H.E. Gendelman Oxidative stress and the pathogenesis of neurodegenerative disorders Int Rev Neurobiol 82 2007 297 325
27. M.V. Sofroniew, and H.V. Vinters Astrocytes: biology and pathology Acta Neuropathol 119 2010 7 35
28. X. Song, M. Bao, D. Li, and Y.M. Li Advanced glycation in d-galactose induced mouse aging model Mech Ageing Dev 108 1999 239 251 (Pubitemid 29240629)
29. D. Trotti, N.C. Danbolt, and A. Volterra Glutamate transporters are oxidant-vulnerable: a molecular link between oxidative and excitotoxic neurodegeneration? Trends Pharmacol Sci 19 1998 328 334 (Pubitemid 28389731)
30. R. Ventura, and K.M. Harris Three-dimensional relationships between hippocampal synapses and astrocytes J Neurosci 19 1999 6897 6906 (Pubitemid 29380118)
31. A. Verkhratsky, and F. Kirchhoff Glutamate-mediated neuronal-glial transmission J Anat 210 2007 651 660 (Pubitemid 46851000)
32. D.M. Wu, J. Lu, Y.L. Zheng, Z. Zhou, Q. Shan, and D.F. Ma Purple sweet potato color repairs d-galactose-induced spatial learning and memory impairment by regulating the expression of synaptic proteins Neurobiol Learn Mem 90 2008 19 27
33. X.N. Zeng, X.L. Sun, L. Gao, Y. Fan, J.H. Ding, and G. Hu Aquaporin-4 deficiency down-regulates glutamate uptake and GLT-1 expression in astrocytes Mol Cell Neurosci 34 2007 34 39 (Pubitemid 46026927)
34. X.L. Zhang, B. Jiang, Z.B. Li, S. Hao, and L.J. An Catalpol ameliorates cognition deficits and attenuates oxidative damage in the brain of senescent mice induced by d-galactose Pharmacol Biochem Behav 88 2007 64 72 (Pubitemid 47379823)