Cyclohexanol analogues are positive modulators of GABA A receptor currents and act as general anaesthetics in vivo

European Journal of Pharmacology

Volumn 667, Issue 1-3, 2011, Pages 175-181

  Hall, Adam C ^a   Griffith, Theanne N ^a   Tsikolia, Maia ^b   Kotey, Francesca O ^a   Gill, Nikhila ^a   Humbert, Danielle J ^a   Watt, Erin E ^a   Yermolina, Yuliya A ^a   Goel, Shikha ^a   El Ghendy, Bahaa ^b   Hall, C Dennis ^b  

^a SMITH COLLEGE   (United States)

^b University of Florida ^*  (United States)

Author keywords

Anaesthetic; Cyclohexanol; GABA; In vitro; In vivo; Oocyte

Indexed keywords

2 METHYLCYCLOHEXANOL; 2 TERT BUTYLCYCLOHEXANOL; 2,6 DI SEC BUTYLCYCLOHEXANOL; 2,6 DI TERT BUTYLCYCLOHEXANOL; 2,6 DIETHYLCYCLOHEXANOL; 2,6 DIISOPROPYLCYCLOHEXANOL; 2,6 DIMETHYLCYCLOHEXANOL; 4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID A RECEPTOR ALPHA1; 4 AMINOBUTYRIC ACID A RECEPTOR BETA2; 4 AMINOBUTYRIC ACID A RECEPTOR GAMMA2; 4 TERT BUTYLCYCLOHEXANOL; ANESTHETIC AGENT; CYCLOHEXANOL; CYCLOHEXANOL DERIVATIVE; CYCLOPENTANOL; PROPOFOL; UNCLASSIFIED DRUG;

ANESTHESIA MECHANISM; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION; TADPOLE; XENOPUS;

ANESTHETICS, GENERAL; ANIMALS; CYCLOHEXANOLS; ELECTRIC CONDUCTIVITY; ELECTROPHYSIOLOGICAL PROCESSES; HUMANS; LARVA; OOCYTES; RECEPTORS, GABA-A; XENOPUS LAEVIS;

EID: 80052029930     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2011.05.058     Document Type: Article

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