메뉴 건너뛰기




Volumn 5, Issue 1, 2011, Pages 21-31

Antigen-expressing immunostimulatory liposomes as a genetically programmable synthetic vaccine

Author keywords

Cell free protein synthesis; DNA vaccination; Synthetic biology; Vaccine

Indexed keywords

BACTERIA (MICROORGANISMS); MUS;

EID: 80052029345     PISSN: 18725325     EISSN: 18725333     Source Type: Journal    
DOI: 10.1007/s11693-010-9066-z     Document Type: Article
Times cited : (30)

References (62)
  • 1
    • 61849159893 scopus 로고    scopus 로고
    • DNA vaccines: developing new strategies to enhance immune responses
    • doi:10.1007/s12026-008-8076-3
    • Abdulhaqq SA, Weiner DB (2008) DNA vaccines: developing new strategies to enhance immune responses. Immunol Res 42(1-3): 219-232. doi: 10. 1007/s12026-008-8076-3.
    • (2008) Immunol Res , vol.42 , Issue.1-3 , pp. 219-232
    • Abdulhaqq, S.A.1    Weiner, D.B.2
  • 2
    • 34548264691 scopus 로고    scopus 로고
    • Diphtheria toxoid-containing microparticulate powder formulations for pulmonary vaccination: preparation, characterization and evaluation in guinea pigs
    • Amidi M, Pellikaan HC, Hirschberg H, de Boer AH, Crommelin DJ, Hennink WE, Kersten G, Jiskoot W (2007) Diphtheria toxoid-containing microparticulate powder formulations for pulmonary vaccination: preparation, characterization and evaluation in guinea pigs. Vaccine 25(37-38): 6818-6829.
    • (2007) Vaccine , vol.25 , Issue.37-38 , pp. 6818-6829
    • Amidi, M.1    Pellikaan, H.C.2    Hirschberg, H.3    de Boer, A.H.4    Crommelin, D.J.5    Hennink, W.E.6    Kersten, G.7    Jiskoot, W.8
  • 4
    • 79953701029 scopus 로고    scopus 로고
    • Robotic large-scale application of wheat cell-free translation to structural studies including membrane proteins
    • doi: 10. 1016/j. nbt. 2010. 07. 003
    • Beebe ET, Makino SI, Nozawa A, Matsubara Y, Frederick RO, Primm JG, Goren MA, Fox BG (2010) Robotic large-scale application of wheat cell-free translation to structural studies including membrane proteins. N Biotechnol. doi: 10. 1016/j. nbt. 2010. 07. 003.
    • (2010) N Biotechnol
    • Beebe, E.T.1    Makino, S.I.2    Nozawa, A.3    Matsubara, Y.4    Frederick, R.O.5    Primm, J.G.6    Goren, M.A.7    Fox, B.G.8
  • 5
    • 4744351698 scopus 로고    scopus 로고
    • Cell-free synthesis of a functional ion channel in the absence of a membrane and in the presence of detergent
    • Berrier C, Park KH, Abes S, Bibonne A, Betton JM, Ghazi A (2004) Cell-free synthesis of a functional ion channel in the absence of a membrane and in the presence of detergent. Biochemistry 43(39): 12585-12591.
    • (2004) Biochemistry , vol.43 , Issue.39 , pp. 12585-12591
    • Berrier, C.1    Park, K.H.2    Abes, S.3    Bibonne, A.4    Betton, J.M.5    Ghazi, A.6
  • 7
    • 46949091517 scopus 로고    scopus 로고
    • Refinement and standardization of synthetic biological parts and devices
    • Canton B, Labno A, Endy D (2008) Refinement and standardization of synthetic biological parts and devices. Nat Biotech 26(7): 787-793. doi: http://www. nature. com/nbt/journal/v26/n7/suppinfo/nbt1413_S1. html.
    • (2008) Nat Biotech , vol.26 , Issue.7 , pp. 787-793
    • Canton, B.1    Labno, A.2    Endy, D.3
  • 9
    • 20044366052 scopus 로고    scopus 로고
    • Americans' responses to the 2004 influenza vaccine shortage
    • DesRoches C, Blendon R, Benson J (2005) Americans' responses to the 2004 influenza vaccine shortage. Health Aff 24(3): 822.
    • (2005) Health Aff , vol.24 , Issue.3 , pp. 822
    • Desroches, C.1    Blendon, R.2    Benson, J.3
  • 10
    • 21344448185 scopus 로고    scopus 로고
    • Particle size and surface charge affect particle uptake by human dendritic cells in an in vitro model
    • Foged C, Brodin B, Frokjaer S, Sundblad A (2005) Particle size and surface charge affect particle uptake by human dendritic cells in an in vitro model. Int J Pharm 298(2): 315-322.
    • (2005) Int J Pharm , vol.298 , Issue.2 , pp. 315-322
    • Foged, C.1    Brodin, B.2    Frokjaer, S.3    Sundblad, A.4
  • 11
    • 70350075480 scopus 로고    scopus 로고
    • Hpv vaccines: preclinical development
    • Gissmann L (2009) Hpv vaccines: preclinical development. Arch Med Res 40(6): 466-470.
    • (2009) Arch Med Res , vol.40 , Issue.6 , pp. 466-470
    • Gissmann, L.1
  • 12
    • 71549135217 scopus 로고    scopus 로고
    • Cell-free translation of integral membrane proteins into unilamelar liposomes
    • doi:10.1016/S0076-6879(09)63037-8
    • Goren MA, Nozawa A, Makino S, Wrobel RL, Fox BG (2009) Cell-free translation of integral membrane proteins into unilamelar liposomes. Methods Enzymol 463: 647-673. doi: 10. 1016/S0076-6879(09)63037-8.
    • (2009) Methods Enzymol , vol.463 , pp. 647-673
    • Goren, M.A.1    Nozawa, A.2    Makino, S.3    Wrobel, R.L.4    Fox, B.G.5
  • 13
    • 33947145756 scopus 로고    scopus 로고
    • Cell-free analysis of tail-anchor protein targeting to membranes
    • doi:10.1016/j.ymeth.2006.07.004
    • Henderson MP, Billen LP, Kim PK, Andrews DW (2007) Cell-free analysis of tail-anchor protein targeting to membranes. Methods 41(4): 427-438. doi: 10. 1016/j. ymeth. 2006. 07. 004.
    • (2007) Methods , vol.41 , Issue.4 , pp. 427-438
    • Henderson, M.P.1    Billen, L.P.2    Kim, P.K.3    Andrews, D.W.4
  • 15
    • 0037105643 scopus 로고    scopus 로고
    • Risk factors for subsequent cervicovaginal human papillomavirus (hpv) infection and the protective role of antibodies to hpv16 viruslike particles
    • doi:10.1086/342972
    • Ho GY, Studentsov Y, Hall CB, Bierman R, Beardsley L, Lempa M, Burk RD (2002) Risk factors for subsequent cervicovaginal human papillomavirus (HPV) infection and the protective role of antibodies to HPV-16 virus-like particles. J Infect Dis 186(6): 737-742. doi: 10. 1086/342972.
    • (2002) J Infect Dis , vol.186 , Issue.6 , pp. 737-742
    • Ho, G.Y.1    Studentsov, Y.2    Hall, C.B.3    Bierman, R.4    Beardsley, L.5    Lempa, M.6    Burk, R.D.7
  • 16
    • 0024424554 scopus 로고
    • The immunoglobulin g subclass responses of mice to influenza a virus: the effect of mouse strain, and the neutralizing abilities of individual protein a-purified subclass antibodies
    • Hocart MJ, Mackenzie JS, Stewart GA (1989) The immunoglobulin g subclass responses of mice to influenza a virus: the effect of mouse strain, and the neutralizing abilities of individual protein a-purified subclass antibodies. J Gen Virol 70(Pt 9): 2439-2448.
    • (1989) J Gen Virol , vol.70 , Issue.Pt 9 , pp. 2439-2448
    • Hocart, M.J.1    Mackenzie, J.S.2    Stewart, G.A.3
  • 17
    • 27644492741 scopus 로고    scopus 로고
    • Two doses of parenterally administered split influenza virus vaccine elicited high serum igg concentrations which effectively limited viral shedding upon challenge in mice
    • doi:10.1111/j.1365-3083.2005.01666.x
    • Hovden AO, Cox RJ, Madhun A, Haaheim LR (2005) Two doses of parenterally administered split influenza virus vaccine elicited high serum igg concentrations which effectively limited viral shedding upon challenge in mice. Scand J Immunol 62(4): 342-352. doi: 10. 1111/j. 1365-3083. 2005. 01666. x.
    • (2005) Scand J Immunol , vol.62 , Issue.4 , pp. 342-352
    • Hovden, A.O.1    Cox, R.J.2    Madhun, A.3    Haaheim, L.R.4
  • 18
    • 15744391469 scopus 로고    scopus 로고
    • Expression of g protein coupled receptors in a cell-free translational system using detergents and thioredoxin-fusion vectors
    • Ishihara G, Goto M, Saeki M, Ito K, Hori T, Kigawa T, Shirouzu M, Yokoyama S (2005) Expression of g protein coupled receptors in a cell-free translational system using detergents and thioredoxin-fusion vectors. Protein Expr Purif 41(1): 27-37.
    • (2005) Protein Expr Purif , vol.41 , Issue.1 , pp. 27-37
    • Ishihara, G.1    Goto, M.2    Saeki, M.3    Ito, K.4    Hori, T.5    Kigawa, T.6    Shirouzu, M.7    Yokoyama, S.8
  • 19
    • 6344283046 scopus 로고    scopus 로고
    • Expression of a cascading genetic network within liposomes
    • Ishikawa K, Sato K, Shima Y, Urabe I, Yomo T (2004) Expression of a cascading genetic network within liposomes. FEBS Lett 576(3): 387-390.
    • (2004) FEBS Lett , vol.576 , Issue.3 , pp. 387-390
    • Ishikawa, K.1    Sato, K.2    Shima, Y.3    Urabe, I.4    Yomo, T.5
  • 20
    • 53949093950 scopus 로고    scopus 로고
    • An integrated cell-free metabolic platform for protein production and synthetic biology
    • doi:10.1038/msb.2008.57
    • Jewett MC, Calhoun KA, Voloshin A, Wuu JJ, Swartz JR (2008) An integrated cell-free metabolic platform for protein production and synthetic biology. Mol Syst Biol 4: 220. doi: 10. 1038/msb. 2008. 57.
    • (2008) Mol Syst Biol , vol.4 , pp. 220
    • Jewett, M.C.1    Calhoun, K.A.2    Voloshin, A.3    Wuu, J.J.4    Swartz, J.R.5
  • 21
    • 79953724336 scopus 로고    scopus 로고
    • Advances in cell-free protein synthesis for the functional and structural analysis of membrane proteins
    • doi: 10. 1016/j. nbt. 2010. 07. 002
    • Junge F, Haberstock S, Roos C, Stefer S, Proverbio D, Dotsch V, Bernhard F (2010) Advances in cell-free protein synthesis for the functional and structural analysis of membrane proteins. N Biotechnol. doi: 10. 1016/j. nbt. 2010. 07. 002.
    • (2010) N Biotechnol
    • Junge, F.1    Haberstock, S.2    Roos, C.3    Stefer, S.4    Proverbio, D.5    Dotsch, V.6    Bernhard, F.7
  • 22
    • 34147092704 scopus 로고    scopus 로고
    • Cell-free production of scfv fusion proteins: an efficient approach for personalized lymphoma vaccines
    • doi:10.1182/blood-2006-07-030593
    • Kanter G, Yang J, Voloshin A, Levy S, Swartz JR, Levy R (2007) Cell-free production of scfv fusion proteins: an efficient approach for personalized lymphoma vaccines. Blood 109(8): 3393-3399. doi: 10. 1182/blood-2006-07-030593.
    • (2007) Blood , vol.109 , Issue.8 , pp. 3393-3399
    • Kanter, G.1    Yang, J.2    Voloshin, A.3    Levy, S.4    Swartz, J.R.5    Levy, R.6
  • 23
    • 54349108394 scopus 로고    scopus 로고
    • Replication of genetic information with self-encoded replicase in liposomes
    • doi:10.1002/cbic.200800360
    • Kita H, Matsuura T, Sunami T, Hosoda K, Ichihashi N, Tsukada K, Urabe I, Yomo T (2008) Replication of genetic information with self-encoded replicase in liposomes. Chembiochem 9(15): 2403-2410. doi: 10. 1002/cbic. 200800360.
    • (2008) Chembiochem , vol.9 , Issue.15 , pp. 2403-2410
    • Kita, H.1    Matsuura, T.2    Sunami, T.3    Hosoda, K.4    Ichihashi, N.5    Tsukada, K.6    Urabe, I.7    Yomo, T.8
  • 24
    • 61749101130 scopus 로고    scopus 로고
    • Cpg oligonucleotides as adjuvants for vaccines targeting infectious diseases
    • Klinman DM, Klaschik S, Sato T, Tross D (2009) Cpg oligonucleotides as adjuvants for vaccines targeting infectious diseases. Adv Drug Deliv Rev 61(3): 248-255.
    • (2009) Adv Drug Deliv Rev , vol.61 , Issue.3 , pp. 248-255
    • Klinman, D.M.1    Klaschik, S.2    Sato, T.3    Tross, D.4
  • 26
    • 70349446448 scopus 로고    scopus 로고
    • Efficient induction of cytotoxic t lymphocytes specific for severe acute respiratory syndrome (sars)-associated coronavirus by immunization with surface-linked liposomal peptides derived from a non-structural polyprotein 1a
    • Kohyama S, Ohno S, Suda T, Taneichi M, Yokoyama S, Mori M, Kobayashi A, Hayashi H, Uchida T, Matsui M (2009) Efficient induction of cytotoxic t lymphocytes specific for severe acute respiratory syndrome (sars)-associated coronavirus by immunization with surface-linked liposomal peptides derived from a non-structural polyprotein 1a. Antiviral Res 84(2): 168-177.
    • (2009) Antiviral Res , vol.84 , Issue.2 , pp. 168-177
    • Kohyama, S.1    Ohno, S.2    Suda, T.3    Taneichi, M.4    Yokoyama, S.5    Mori, M.6    Kobayashi, A.7    Hayashi, H.8    Uchida, T.9    Matsui, M.10
  • 27
    • 77952765484 scopus 로고    scopus 로고
    • Production of multi-subunit complexes on liposome through an e.Coli cell-free expression system
    • doi:10.1007/978-1-60327-331-2_14
    • Kuruma Y, Suzuki T, Ueda T (2010) Production of multi-subunit complexes on liposome through an e. Coli cell-free expression system. Methods Mol Biol 607: 161-171. doi: 10. 1007/978-1-60327-331-2_14.
    • (2010) Methods Mol Biol , vol.607 , pp. 161-171
    • Kuruma, Y.1    Suzuki, T.2    Ueda, T.3
  • 28
    • 33645871300 scopus 로고    scopus 로고
    • Human clinical trials of plasmid DNA vaccines
    • doi:10.1016/S0065-2660(05)55002-8
    • Liu MA, Ulmer JB (2005) Human clinical trials of plasmid DNA vaccines. Adv Genet 55: 25-40. doi: 10. 1016/S0065-2660(05)55002-8.
    • (2005) Adv Genet , vol.55 , pp. 25-40
    • Liu, M.A.1    Ulmer, J.B.2
  • 29
    • 56149095844 scopus 로고    scopus 로고
    • Immunogenicity of DNA vaccines in humans: it takes two to tango
    • Lu S (2008) Immunogenicity of DNA vaccines in humans: it takes two to tango. Hum Vaccin 4(6): 449-452.
    • (2008) Hum Vaccin , vol.4 , Issue.6 , pp. 449-452
    • Lu, S.1
  • 30
    • 28844487473 scopus 로고    scopus 로고
    • High-throughput screening of enzyme libraries: in vitro evolution of a beta-galactosidase by fluorescence-activated sorting of double emulsions
    • Mastrobattista E, Taly V, Chanudet E, Treacy P, Kelly BT, Griffiths AD (2005) High-throughput screening of enzyme libraries: in vitro evolution of a beta-galactosidase by fluorescence-activated sorting of double emulsions. Chem Biol 12(12): 1291-1300.
    • (2005) Chem Biol , vol.12 , Issue.12 , pp. 1291-1300
    • Mastrobattista, E.1    Taly, V.2    Chanudet, E.3    Treacy, P.4    Kelly, B.T.5    Griffiths, A.D.6
  • 31
    • 73949118947 scopus 로고    scopus 로고
    • A ctl-based liposomal vaccine capable of inducing protection against heterosubtypic influenza viruses in hla-a*0201 transgenic mice
    • Matsui M, Kohyama S, Suda T, Yokoyama S, Mori M, Kobayashi A, Taneichi M, Uchida T (2010) A ctl-based liposomal vaccine capable of inducing protection against heterosubtypic influenza viruses in hla-a*0201 transgenic mice. Biochem Biophys Res Commun 391(3): 1494-1499.
    • (2010) Biochem Biophys Res Commun , vol.391 , Issue.3 , pp. 1494-1499
    • Matsui, M.1    Kohyama, S.2    Suda, T.3    Yokoyama, S.4    Mori, M.5    Kobayashi, A.6    Taneichi, M.7    Uchida, T.8
  • 32
    • 69549114407 scopus 로고    scopus 로고
    • Neutralizing antibodies against hiv-1: Can we elicit them with vaccines and how much do we need?
    • doi: 310. 1097/COH. 1090b1013e32832f32834a32834d
    • Montefiori DC, Mascola JR (2009) Neutralizing antibodies against hiv-1: Can we elicit them with vaccines and how much do we need? Curr Opin HIV AIDS 4(5): 347-351. doi: 310. 1097/COH. 1090b1013e32832f32834a32834d.
    • (2009) Curr Opin HIV AIDS , vol.4 , Issue.5 , pp. 347-351
    • Montefiori, D.C.1    Mascola, J.R.2
  • 33
    • 38049094546 scopus 로고    scopus 로고
    • Antibody-based hiv-1 vaccines: recent developments and future directions
    • doi:10.1371/journal.pmed.0040348
    • Montefiori D, Sattentau Q, Flores J, Esparza J, Mascola J, Va WGCGH (2007) Antibody-based hiv-1 vaccines: recent developments and future directions. PLoS Med 4(12): 1867-1871. doi: 10. 1371/journal. pmed. 0040348.
    • (2007) PLoS Med , vol.4 , Issue.12 , pp. 1867-1871
    • Montefiori, D.1    Sattentau, Q.2    Flores, J.3    Esparza, J.4    Mascola, J.5    Va, W.G.C.G.H.6
  • 34
    • 77955246394 scopus 로고    scopus 로고
    • Direct integration of cell-free-synthesized connexin-43 into liposomes and hemichannel formation
    • doi: 10. 1111/j. 1742-4658. 2010. 07736. x
    • Moritani Y, Nomura SI, Morita I, Akiyoshi K (2010) Direct integration of cell-free-synthesized connexin-43 into liposomes and hemichannel formation. FEBS J. doi: 10. 1111/j. 1742-4658. 2010. 07736. x.
    • (2010) FEBS J
    • Moritani, Y.1    Nomura, S.I.2    Morita, I.3    Akiyoshi, K.4
  • 35
    • 34548842199 scopus 로고    scopus 로고
    • Protein synthesis in liposomes with a minimal set of enzymes
    • doi:10.1016/j.bbrc.2007.07.201
    • Murtas G, Kuruma Y, Bianchini P, Diaspro A, Luisi PL (2007) Protein synthesis in liposomes with a minimal set of enzymes. Biochem Biophys Res Commun 363(1): 12-17. doi: 10. 1016/j. bbrc. 2007. 07. 201.
    • (2007) Biochem Biophys Res Commun , vol.363 , Issue.1 , pp. 12-17
    • Murtas, G.1    Kuruma, Y.2    Bianchini, P.3    Diaspro, A.4    Luisi, P.L.5
  • 37
    • 77952774821 scopus 로고    scopus 로고
    • Production of membrane proteins through the wheat-germ cell-free technology
    • doi:10.1007/978-1-60327-331-2_17
    • Nozawa A, Nanamiya H, Tozawa Y (2010) Production of membrane proteins through the wheat-germ cell-free technology. Methods Mol Biol 607: 213-218. doi: 10. 1007/978-1-60327-331-2_17.
    • (2010) Methods Mol Biol , vol.607 , pp. 213-218
    • Nozawa, A.1    Nanamiya, H.2    Tozawa, Y.3
  • 39
    • 67349272774 scopus 로고    scopus 로고
    • Synthetic peptides coupled to the surface of liposomes effectively induce sars coronavirus-specific cytotoxic t lymphocytes and viral clearance in hla-a*0201 transgenic mice
    • Ohno S, Kohyama S, Taneichi M, Moriya O, Hayashi H, Oda H, Mori M, Kobayashi A, Akatsuka T, Uchida T, Matsui M (2009) Synthetic peptides coupled to the surface of liposomes effectively induce sars coronavirus-specific cytotoxic t lymphocytes and viral clearance in hla-a*0201 transgenic mice. Vaccine 27(29): 3912-3920.
    • (2009) Vaccine , vol.27 , Issue.29 , pp. 3912-3920
    • Ohno, S.1    Kohyama, S.2    Taneichi, M.3    Moriya, O.4    Hayashi, H.5    Oda, H.6    Mori, M.7    Kobayashi, A.8    Akatsuka, T.9    Uchida, T.10    Matsui, M.11
  • 40
    • 56249122606 scopus 로고    scopus 로고
    • Personalized vaccines: the emerging field of vaccinomics
    • Poland G, Ovsyannikova I, Jacobson R (2008) Personalized vaccines: the emerging field of vaccinomics. Expert Opin Biol Ther 8(11): 1659-1667.
    • (2008) Expert Opin Biol Ther , vol.8 , Issue.11 , pp. 1659-1667
    • Poland, G.1    Ovsyannikova, I.2    Jacobson, R.3
  • 43
    • 42049085289 scopus 로고    scopus 로고
    • Correlates of antibody-mediated protection against hiv infection
    • doi:10.1097/COH.0b013e3282f9ae79
    • Sattentau Q (2008) Correlates of antibody-mediated protection against hiv infection. Curr Opin HIV AIDS 3(3): 368-374. doi: 10. 1097/COH. 0b013e3282f9ae79.
    • (2008) Curr Opin HIV AIDS , vol.3 , Issue.3 , pp. 368-374
    • Sattentau, Q.1
  • 44
    • 0034904102 scopus 로고    scopus 로고
    • Cell-free translation reconstituted with purified components
    • Shimizu Y, Inoue A, Tomari Y, Suzuki T, Yokogawa T, Nishikawa K, Ueda T (2001) Cell-free translation reconstituted with purified components. Nat Biotech 19 (8): 751-755. doi: http://www. nature. com/nbt/journal/v19/n8/suppinfo/nbt0801_751_S1. html.
    • (2001) Nat Biotech , vol.19 , Issue.8 , pp. 751-755
    • Shimizu, Y.1    Inoue, A.2    Tomari, Y.3    Suzuki, T.4    Yokogawa, T.5    Nishikawa, K.6    Ueda, T.7
  • 45
    • 33846108672 scopus 로고    scopus 로고
    • Cell-free synthetic biology: A bottom-up approach to discovery by design
    • doi: 6910. 1038/msb4100104
    • Simpson ML (2006) Cell-free synthetic biology: a bottom-up approach to discovery by design. Mol Syst Biol 2. doi: 6910. 1038/msb4100104.
    • (2006) Mol Syst Biol , vol.2
    • Simpson, M.L.1
  • 46
    • 77950859996 scopus 로고    scopus 로고
    • Botulism and vaccines for its prevention
    • Smith LA (2009) Botulism and vaccines for its prevention. Vaccine 27(Suppl 4): D33-D39.
    • (2009) Vaccine , vol.27 , Issue.SUPPL. 4 , pp. 33-39
    • Smith, L.A.1
  • 47
    • 33748287106 scopus 로고    scopus 로고
    • Femtoliter compartment in liposomes for in vitro selection of proteins
    • doi:10.1016/j.ab.2006.06.040
    • Sunami T, Sato K, Matsuura T, Tsukada K, Urabe I, Yomo T (2006) Femtoliter compartment in liposomes for in vitro selection of proteins. Anal Biochem 357(1): 128-136. doi: 10. 1016/j. ab. 2006. 06. 040.
    • (2006) Anal Biochem , vol.357 , Issue.1 , pp. 128-136
    • Sunami, T.1    Sato, K.2    Matsuura, T.3    Tsukada, K.4    Urabe, I.5    Yomo, T.6
  • 48
    • 77952781387 scopus 로고    scopus 로고
    • Synthesis of functional proteins within liposomes
    • doi:10.1007/978-1-60327-331-2_20
    • Sunami T, Matsuura T, Suzuki H, Yomo T (2010) Synthesis of functional proteins within liposomes. Methods Mol Biol 607: 243-256. doi: 10. 1007/978-1-60327-331-2_20.
    • (2010) Methods Mol Biol , vol.607 , pp. 243-256
    • Sunami, T.1    Matsuura, T.2    Suzuki, H.3    Yomo, T.4
  • 49
    • 0030470545 scopus 로고    scopus 로고
    • Size effect on systemic and mucosal immune responses induced by oral administration of biodegradable microspheres
    • Tabata Y, Inoue Y, Ikada Y (1996) Size effect on systemic and mucosal immune responses induced by oral administration of biodegradable microspheres. Vaccine 14(17-18): 1677-1685.
    • (1996) Vaccine , vol.14 , Issue.17-18 , pp. 1677-1685
    • Tabata, Y.1    Inoue, Y.2    Ikada, Y.3
  • 52
    • 33746770419 scopus 로고    scopus 로고
    • Induction of differential t-cell epitope by plain- and liposome-coupled antigen
    • doi:10.1021/bc060024g
    • Taneichi M, Tanaka Y, Kasai M, Mori M, Nishida M, Yamamura H, Mizuguchi J, Uchida T (2006b) Induction of differential t-cell epitope by plain- and liposome-coupled antigen. Bioconj Chem 17(4): 899-904. doi: 10. 1021/bc060024g.
    • (2006) Bioconj Chem , vol.17 , Issue.4 , pp. 899-904
    • Taneichi, M.1    Tanaka, Y.2    Kasai, M.3    Mori, M.4    Nishida, M.5    Yamamura, H.6    Mizuguchi, J.7    Uchida, T.8
  • 53
    • 58849087222 scopus 로고    scopus 로고
    • A phase i trial of a human papillomavirus DNA vaccine for hpv16 + cervical intraepithelial neoplasia 2/3
    • doi:10.1158/1078-0432.CCR-08-1725
    • Trimble CL, Peng S, Kos F, Gravitt P, Viscidi R, Sugar E, Pardoll D, Wu TC (2009) A phase i trial of a human papillomavirus DNA vaccine for hpv16 + cervical intraepithelial neoplasia 2/3. Clin Cancer Res 15(1): 361-367. doi: 10. 1158/1078-0432. CCR-08-1725.
    • (2009) Clin Cancer Res , vol.15 , Issue.1 , pp. 361-367
    • Trimble, C.L.1    Peng, S.2    Kos, F.3    Gravitt, P.4    Viscidi, R.5    Sugar, E.6    Pardoll, D.7    Wu, T.C.8
  • 55
    • 77950055495 scopus 로고    scopus 로고
    • The wheat germ cell-free protein synthesis system: a key tool for novel malaria vaccine candidate discovery
    • doi:10.1016/j.actatropica.2009.10.024
    • Tsuboi T, Takeo S, Arumugam TU, Otsuki H, Torii M (2010a) The wheat germ cell-free protein synthesis system: a key tool for novel malaria vaccine candidate discovery. Acta Trop 114(3): 171-176. doi: 10. 1016/j. actatropica. 2009. 10. 024.
    • (2010) Acta Trop , vol.114 , Issue.3 , pp. 171-176
    • Tsuboi, T.1    Takeo, S.2    Arumugam, T.U.3    Otsuki, H.4    Torii, M.5
  • 56
    • 77952786248 scopus 로고    scopus 로고
    • An efficient approach to the production of vaccines against the malaria parasite
    • doi:10.1007/978-1-60327-331-2_8
    • Tsuboi T, Takeo S, Sawasaki T, Torii M, Endo Y (2010b) An efficient approach to the production of vaccines against the malaria parasite. Methods Mol Biol 607: 73-83. doi: 10. 1007/978-1-60327-331-2_8.
    • (2010) Methods Mol Biol , vol.607 , pp. 73-83
    • Tsuboi, T.1    Takeo, S.2    Sawasaki, T.3    Torii, M.4    Endo, Y.5
  • 57
    • 40049093888 scopus 로고    scopus 로고
    • Clinical application of surface-linked liposomal antigens
    • Uchida T, Taneichi M (2008) Clinical application of surface-linked liposomal antigens. Mini Rev Med Chem 8(2): 184-192.
    • (2008) Mini Rev Med Chem , vol.8 , Issue.2 , pp. 184-192
    • Uchida, T.1    Taneichi, M.2
  • 58
    • 33750862932 scopus 로고    scopus 로고
    • Vaccine manufacturing: challenges and solutions
    • doi:10.1038/nbt1261
    • Ulmer JB, Valley U, Rappuoli R (2006) Vaccine manufacturing: challenges and solutions. Nat Biotechnol 24(11): 1377-1383. doi: 10. 1038/nbt1261.
    • (2006) Nat Biotechnol , vol.24 , Issue.11 , pp. 1377-1383
    • Ulmer, J.B.1    Valley, U.2    Rappuoli, R.3
  • 60
  • 61
    • 33747362667 scopus 로고    scopus 로고
    • Molecular aspects of microparticle phagocytosis by dendritic cells
    • Yoshida M, Babensee JE (2006) Molecular aspects of microparticle phagocytosis by dendritic cells. J Biomater Sci Polym Ed 17(8): 893-907.
    • (2006) J Biomater Sci Polym Ed , vol.17 , Issue.8 , pp. 893-907
    • Yoshida, M.1    Babensee, J.E.2
  • 62
    • 77951985187 scopus 로고    scopus 로고
    • Efficacy of a potential trivalent vaccine based on hc fragments of botulinum toxins a, b, and e produced in a cell-free expression system
    • doi:10.1128/CVI.00496-09
    • Zichel R, Mimran A, Keren A, Barnea A, Steinberger-Levy I, Marcus D, Turgeman A, Reuveny S (2010) Efficacy of a potential trivalent vaccine based on hc fragments of botulinum toxins a, b, and e produced in a cell-free expression system. Clin Vaccine Immunol 17(5): 784-792. doi: 10. 1128/CVI. 00496-09.
    • (2010) Clin Vaccine Immunol , vol.17 , Issue.5 , pp. 784-792
    • Zichel, R.1    Mimran, A.2    Keren, A.3    Barnea, A.4    Steinberger-Levy, I.5    Marcus, D.6    Turgeman, A.7    Reuveny, S.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.