Bacopa monnieri and its constituents is hypotensive in anaesthetized rats and vasodilator in various artery types

Journal of Ethnopharmacology

Volumn 137, Issue 1, 2011, Pages 790-795

  Kamkaew, Natakorn ^a   Scholfield, C Norman ^a   Ingkaninan, Kornkanok ^a   Maneesai, Putcharawipa ^a   Parkington, Helena C ^b   Tare, Marianne ^b   Chootip, Krongkarn ^a  

^a NARESUAN UNIVERSITY   (Thailand)

^b MONASH UNIVERSITY   (Australia)

Author keywords

Artery; Bacopa monnieri; Blood pressure; Calcium; Vasodilation

Indexed keywords

BACOPA MONNIERI EXTRACT; BACOPASIDE II; BACOSIDE A3; CAFFEINE; CALCIUM; INDOMETACIN; N(G) NITROARGININE METHYL ESTER; PHENYLEPHRINE; POTASSIUM; SAPONIN DERIVATIVE; UNCLASSIFIED DRUG; VASODILATOR AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACOPA MONNIERI; BASILAR ARTERY; CALCIUM TRANSPORT; CONTROLLED STUDY; DEPOLARIZATION; DIASTOLIC BLOOD PRESSURE; DRUG POTENCY; ENDOTHELIUM; FEMORAL ARTERY; HEART RATE; HYPERTENSION; HYPOTENSION; IC 50; IN VITRO STUDY; MALE; NONHUMAN; RAT; SARCOPLASMIC RETICULUM; SYSTOLIC BLOOD PRESSURE; VASODILATATION;

ANESTHESIA, GENERAL; ANIMALS; ANTIHYPERTENSIVE AGENTS; ARTERIES; BACOPA; BLOOD PRESSURE; CALCIUM SIGNALING; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIUM, VASCULAR; ENZYME INHIBITORS; HEART RATE; HYPOTENSION; INFUSIONS, INTRAVENOUS; MALE; NITRIC OXIDE SYNTHASE; PLANT COMPONENTS, AERIAL; PLANT EXTRACTS; PLANTS, MEDICINAL; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; RATS; RATS, WISTAR; SARCOPLASMIC RETICULUM; VASODILATION; VASODILATOR AGENTS;

BACOPA MONNIERI; RATTUS;

EID: 80052021548     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2011.06.045     Document Type: Article

References (22)

1. S. Chalmers, M.L. Olson, D. MacMillan, R.D. Rainbow, and J.G. McCarron Ion channels in smooth muscle: regulation by the sarcoplasmic reticulum and mitochondria Cell Calcium 42 2007 447 466 (Pubitemid 47264012)
2. S. Channa, A. Dar, M. Yaqoob, S. Anjum, Z. Sultani, and A. Rahman Broncho-vasodilatory activity of fractions and pure constituents isolated from Bacopa monniera Journal of Ethnopharmacology 86 2003 27 35 (Pubitemid 36398655)
3. K. Chootip, K.F. Ness, Y. Wang, A.M. Gurney, and C. Kennedy Regional variation in P2 receptor expression in the rat pulmonary arterial circulation British Journal of Pharmacology 137 2002 637 646 (Pubitemid 35333089)
4. S. Chulia, M.D. Ivorra, S. Martinez, M. Elorriaga, M. Valiente, M.A. Noguera, C. Lugnier, C. Advenier, and P. D'Ocon Relationships between structure and vascular activity in a series of benzylisoquinolines British Journal of Pharmacology 122 1997 409 416 (Pubitemid 27429714)
5. M.J.A.P. Daemen, and J.G.R. De Mey Regional heterogeneity of arterial structural changes Hypertension 25 1995 464 473
6. A. Dar, and S. Channa Relaxant effect of ethanol extract of Bacopa monniera on trachea, pulmonary artery and aorta from rabbit and guinea-pig Phytotherapy Research 11 1997 323 325 (Pubitemid 27250270)
7. A. Dar, and S. Channa Calcium antagonistic activity of Bacopa monniera on vascular and intestinal smooth muscles of rabbit and guinea-pig Journal of Ethnopharmacology 66 1999 167 174 (Pubitemid 29307915)
8. A. Das, G. Shanker, C. Nath, R. Pal, S. Singh, and H.K. Singh A comparative study in rodents of standardized extracts of Bacopa monniera and Ginkgo biloba: anticholinesterase and cognitive enhancing activities Pharmacology, Biochemistry and Behavior 73 2002 893 900 (Pubitemid 35246239)
9. M. Dhanasekaran, B. Tharakan, L.A. Holcomb, A.R. Hitt, K.A. Young, and B.V. Manyam Neuroprotective mechanisms of Ayurvedic antidementia botanical Bacopa monniera Phytotherapy Research 21 2007 965 969 (Pubitemid 47582771)
10. K.J. Gohil, and J.A. Patel A review on Bacopa monniera: current research and future prospects International Journal of Green Pharmacy 4 2010 1 9
11. N. Limpeanchob, S. Jaipan, S. Rattanakaruna, W. Phrompittayarat, and K. Ingkaninan Neuroprotective effect of Bacopa monnieri on beta-amyloid-induced cell death in primary cortical culture Journal of Ethnopharmacology 120 2008 112 117
12. M.Q. Mazzuca, M.E. Wlodek, N.M. Dragomir, H.C. Parkington, and M. Tare Uteroplacental insufficiency programs regional vascular dysfunction and alters arterial stiffness in female offspring The Journal of Physiology 588 2010 1997 2010
13. E.D. Michelakis, H.L. Reeve, J.M. Huang, S. Tolarova, D.P. Nelson, E.K. Weir, and S.L. Archer Potassium channel diversity in vascular smooth muscle cells Canadian Journal of Physiology and Pharmacology 75 1997 889 897 (Pubitemid 27451808)
14. M. Nandave, S.K. Ojha, S. Joshi, S. Kumari, and D.S. Arya Cardioprotective effect of Bacopa monneira against isoproterenol-induced myocardial necrosis in rats International Journal of Pharmacology 3 2007 385 392 (Pubitemid 351330636)
15. W. Phrompittayarat, W. Putalun, H. Tanaka, K. Jetiyanon, S. Wittaya-areekul, and K. Ingkaninan Determination of pseudojujubogenin glycosides from Brahmi based on immunoassay using a monoclonal antibody against bacopaside I Phytochemical Analysis 18 2007 411 418 (Pubitemid 47422797)
16. W. Phrompittayarat, W. Putalun, H. Tanaka, S. Wittaya-areekul, K. Jetiyanon, and K. Ingkaninan An enzyme-linked immunosorbant assay using polyclonal antibodies against bacopaside I Analytica Chimica Acta 584 2007 1 6 (Pubitemid 46123182)
17. R. Prasad, U.S. Bagde, P. Puspangadan, and A. Varma Bacopa monniera L.: pharmacological aspects and case study involving Piriformospora indica International Journal of Integrative Biology 3 2008 100 110
18. A. Russo, and F. Borrelli Bacopa monniera, a reputed nootropic plant: an overview Phytomedicine 12 2005 305 317 (Pubitemid 40471030)
19. 2+ sensitivity of smooth muscle and nonmuscle myosin II: modulated by G proteins, kinases, and myosin phosphatase Physiological Reviews 83 2003 1325 1358 (Pubitemid 37222274)
20. Thorne Research Bacopa monniera Alternative Medicine Review 9 2004 79 85
21. N. Uabundit, J. Wattanathorn, S. Mucimapura, and K. Ingkaninan Cognitive enhancement and neuroprotective effects of Bacopa monnieri in Alzheimer's disease model Journal of Ethnopharmacology 127 2010 26 31
22. V.R. Vollala, S. Upadhya, and S. Nayak Effect of Bacopa monniera Linn. (brahmi) extract on learning and memory in rats: a behavioral study Journal of Veterinary Behavior Clinical Applications and Research 5 2010 69 74