Design, synthesis and evaluation of novel indomethacin-flavonoid mutual prodrugs as safer NSAIDs

Medicinal Chemistry Research

Volumn 20, Issue 6, 2011, Pages 687-694

  Sawraj, Shruti ^a   Bhardawaj, Tilak R ^a   Sharma, Pritam D ^a  

^a PANJAB UNIVERSITY   (India)

Author keywords

Conjugates; Flavonoid; Indomethacin; NSAIDs; Ulcerogenicity

Indexed keywords

FLAVONOID; HESPERTIN; INDOMETACIN; NARINGENIN; NONSTEROID ANTIINFLAMMATORY AGENT; PRODRUG; UNCLASSIFIED DRUG;

ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CONJUGATE; CONTROLLED STUDY; DRUG CONJUGATION; DRUG DESIGN; DRUG MIXTURE; DRUG SAFETY; DRUG SCREENING; DRUG SYNTHESIS; ESTERIFICATION; INFRARED SPECTROSCOPY; MALE; MASS SPECTROMETRY; MELTING POINT; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; THIN LAYER CHROMATOGRAPHY; ULCEROGENESIS;

EID: 80052021381     PISSN: 10542523     EISSN: 15548120     Source Type: Journal    
DOI: 10.1007/s00044-010-9363-9     Document Type: Article

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