Midlife motivational abilities predict apathy and depression in Alzheimer disease: The aging, demographics, and memory study

Journal of Geriatric Psychiatry and Neurology

Volumn 24, Issue 3, 2011, Pages 151-160

  Mortby, Moyra Elizabeth ^a   Maercker, Andreas ^a   Forstmeier, Simon ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

Alzheimer disease; apathy; behavioral and psychological symptoms of dementia; dementia; depression; motivation

Indexed keywords

AGED; ALZHEIMER DISEASE; APATHY; ARTICLE; CONTROLLED STUDY; DEPRESSION; DISEASE COURSE; DISEASE SEVERITY; FEMALE; FOLLOW UP; GOAL ATTAINMENT; HUMAN; MAJOR CLINICAL STUDY; MALE; MIDLIFE MOTIVATIONAL ABILITY; MILD COGNITIVE IMPAIRMENT; MOTIVATION; NEUROPSYCHOLOGICAL TEST; POPULATION RESEARCH; PREDICTOR VARIABLE; PRIORITY JOURNAL; REFERENCE DATABASE;

AGED; AGED, 80 AND OVER; AGING; ALZHEIMER DISEASE; APATHY; COGNITION DISORDERS; DEPRESSION; DEPRESSIVE DISORDER; DISEASE PROGRESSION; FEMALE; HUMANS; LONGITUDINAL STUDIES; MALE; MEMORY; MIDDLE AGED; MOTIVATION; NEUROPSYCHOLOGICAL TESTS;

EID: 80051997582     PISSN: 08919887     EISSN: 15525708     Source Type: Journal    
DOI: 10.1177/0891988711409409     Document Type: Article

References (47)

1. Lyketsos CG, Lopez O, Jones B, Fitzpatrick AL, Breitner J, DeKosky S. Prevalence of neuropsychiatric symptoms in dementia and mild cognitive impairment: results from the cardiovascular health study. JAMA. 2002 ; 288 (12). 1475-1483
2. Benoit M, Andrieu S, Lechowski L, Gillette-Guyonnet S, Robert PH, Vellas B. Apathy and depression in Alzheimer's disease are associated with functional deficit and psychotropic prescription. Int J Geriatr Psychiatry. 2008 ; 23 (4). 409-414 (Pubitemid 351566338)
3. Palmer K, Di Iulio F, Varsi AE, et al. Neuropsychiatric predictors of progression from amnestic-mild cognitive impairment to Alzheimer's disease: the role of depression and apathy. J Alzheimer Dis. 2010 ; 20 (1). 175-183
4. Zuidema SU, de Jonghe JF, Verhey FR, Koopmans RT. Predictors of neuropsychiatric symptoms in nursing home patients: influence of gender and dementia severity. Int J Geriatr Psychiatry. 2009 ; 24 (10). 1079-1086
5. Treiber KA, Lyketsos CG, Corcoran C, et al. Vascular factors and risk for neuropsychiatric symptoms in Alzheimer's disease: the Cache County Study. Int Psychogeriatr. 2008 ; 20 (3). 538-553 (Pubitemid 351465551)
6. Zuidema SU, de Jonghe JF, Verhey FR, Koopmans RT. Environmental correlates of neuropsychiatric symptoms in nursing home patients with dementia. Int J Geriatr Psychiatry. 2010 ; 25 (1). 14-22
7. Clarke DE, van Reekum R, Simard M, et al. Apathy in dementia: clinical and sociodemographic correlates. J Neuropsychiatry Clin Neurosci. 2008 ; 20 (3). 337-347
8. Gilley DW, Wilson RS, Bienias JL, Bennett DA, Evans DA. Predictors of depressive symptoms in persons with Alzheimer's disease. J Gerontol B Psychol Sci Soc Sci. 2004 ; 59 (2). P75 - P83
9. Archer N, Brown RG, Reeves SJ, et al. Premorbid personality and behavioral and psychological symptoms in probable Alzheimer disease. Am J Geriatr Psychiatry. 2007 ; 15 (3). 202-213
10. Robert P, Onyike CU, Leentjens AF, et al. Proposed diagnostic criteria for apathy in Alzheimer's disease and other neuropsychiatric disorders. Eur Psychiatry. 2009 ; 24 (2). 98-104
11. Johnson CL, Barer BM. Coping and a sense of control amongst the oldest old: an exploratory analysis. J Aging Studies. 1993 ; 7: 67-80
12. Staudinger UM, Freund AM, Linden M, Maas I The Berlin Aging Study: Aging from 70 to 100. Baltes PB Mayer KU, ed. New York, NY: Cambridge ; 1999: 302-328.
13. Kruglanski AW, Thompson EP, Higgins ET, et al. To "do the right thing" or to "just do it": locomotion and assessment as distinct self-regulatory imperatives. J Pers Soc Psychol. 2000 ; 79 (5). 793-815
14. Bandura A Self-Efficacy: The Exercise of Control. New York, NY: Freeman ; 1997 :
15. Rholes WS, Michas L, Shroff J. Action control as a vulnerability factor in dysphoria. Cogn Ther Res. 1989 ; 13 (3). 263-274 (Pubitemid 19167720)
16. Tangney JP, Baumeister RF, Boone AL. High self-control predicts good adjustment, less pathology, better grades, and interpersonal success. J Pers. 2004 ; 72 (2). 271-324 (Pubitemid 38422899)
17. Gabryelewicz T, Styczynska M, Luczywek E, et al. The rate of conversion of mild cognitive impairment to dementia: predictive role of depression. Int J Geriatr Psychiatry. 2007 ; 22 (6). 563-567 (Pubitemid 46951755)
18. Modrego PJ, Ferrandez J. Depression in patients with mild cognitive impairment increases the risk of developing dementia of Alzheimer type: a prospective cohort study. Arch Neurol. 2004 ; 61 (8). 1290-1293 (Pubitemid 39062687)
19. Bartolini M, Coccia M, Luzzi S, Provinciali L, Ceravolo MG. Motivational symptoms of depression mask preclinical Alzheimer's disease in elderly subjects. Dement Geriatr Cogn Disord. 2005 ; 19 (1). 31-36 (Pubitemid 39664186)
20. Berger AK, Fratiglioni L, Forsell Y, Winblad B, Backman L. The occurrence of depressive symptoms in the preclinical phase of AD: a population-based study. Neurology. 1999 ; 53 (9). 1998-2002
21. Mulin E, Leone E, Dujardin K, et al. Diagnostic criteria for apathy in clinical practice. Int J Geriatr Psychiatry. 2011 ; 26: 158-165
22. Robert PH, Berr C, Volteau M, et al. Apathy in patients with mild cognitive impairment and the risk of developing dementia of Alzheimer's disease: a one-year follow-up study. Clin Neurol Neurosurg. 2006 ; 108 (8). 733-736 (Pubitemid 44709787)
23. Teng E, Lu PH, Cummings JL. Neuropsychiatric symptoms are associated with progression from mild cognitive impairment to Alzheimer's disease. Dement Geriatr Cogn Disord. 2007 ; 24 (4). 253-259 (Pubitemid 47482071)
24. Robert PH, Berr C, Volteau M, et al. Importance of lack of interest in patients with mild cognitive impairment. Am J Geriatr Psychiatry. 2008 ; 16 (9). 770-776
25. Brown RG, Pluck G. Negative symptoms: the 'pathology' of motivation and goal-directed behaviour. Trends Neurosci. 2000 ; 23 (9). 412-417
26. Forstmeier S, Maercker A. Motivational reserve: Lifetime motivational abilities influence cognitive and emotional health in old age. Psychol Aging. 2008 ; 23 (4). 886-899
27. Andel R, Crowe M, Pedersen NL, et al. Complexity of work and risk of Alzheimer's disease: a population-based study of Swedish twins. J Gerontol B Psychol Sci Soc Sci. 2005 ; 60 (5). P251 - P258
28. Juster FT, Suzman R. An overview of the health and retirement study. J Hum Resources. 1995 ; 30 (suppl). 135-145
29. Langa KM, Plassman BL, Wallace RB, et al. The aging, demographics, and memory study: study design and methods. Neuroepidemiology. 2005 ; 25 (4). 181-191 (Pubitemid 41540659)
30. Plassman BL, Langa KM, Fisher GG, et al. Prevalence of cognitive impairment without dementia in the United States. Ann Intern Med. 2008 ; 148 (6). 427-434 (Pubitemid 351665442)
31. Association AP Diagnostic and Statistical Manual of Mental Disorders. 4 th ed. 2000. Washington, DC: APA ; 2000 :
32. Petersen RC, Smith GE, Waring SC, Ivnik RJ, Tangalos EG, Kokmen E. Mild cognitive impairment: clinical characterization and outcome. Arch Neurol. 1999 ; 56 (3). 303-308 (Pubitemid 29120227)
33. Bigler ED, Lowry CM, Anderson CV, Johnson SC, Terry J, Steed M. Dementia, quantitative neuroimaging, and apolipoprotein E genotype. Am J Neuroradiol. 2000 ; 21 (10). 1857-1868
34. Cummings JL, Mega M, Gray K, Rosenberg-Thompson S, Carusi DA, Gornbein J. The neuropsychiatric inventory: comprehensive assessment of psychopathology in dementia. Neurology. 1994 ; 44 (12). 2308-2314 (Pubitemid 24382728)
35. Connor DJ, Sabbagh MN, Cummings JL. Comment on administration and scoring of the neuropsychiatric inventory in clinical trials. Alzheimers Dement. 2008 ; 4 (6). 390-394
36. Peterson NG, Mumford MD, Borman WC, Jeanneret PR, Fleishman EA An Occupational Information System for the 21st Century: The Development of O*NET. Washington, DC: American Psychological Association ; 1999 :
37. Nolte MA, Servais MA. Occupation and Industry Coding in HRS/AHEAD (Health and Retirement Study Doccumentation Report DR-021). 2008 ;:
38. Folstein MF, Folstein SE, McHugh PR. "Mini-mental state". A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res. 1975 ; 12 (3). 189-198
39. Kuhl J, Fuhrmann A Motivation and Self-Regulation Across the Life Span. Heckhausen J Dweck CS, ed. Cambrige: Cambridge University Press ; 1998: 15-49.
40. Luszczynska A, Gutiérrez DB, Schwarzer R. General self-efficacy in various domains of human functioning: evidence from five countries. Int J Psychol. 2005 ; 40 (5). 80-89 (Pubitemid 40688113)
41. Thompson SC, Cheek PR, Graham MA The Social Psychology of Health. Spacapan S Oskamp S, ed. Newbury Park: Sage ; 1988: 69-93.
42. Wolk S. Situational constraint as a moderator of the locus of control-adjustment relationship. J Consult Clin Psychol. 1976 ; 44 (3). 420-427
43. Kuhl J, Helle P. Motivational and volitional determinants of depression: the degenerated-intention hypothesis. J Abnorm Psychol. 1986 ; 95 (3). 247-251 (Pubitemid 17043222)
44. Brandtstädter J, Rothermund K. The life-course dynamics of goal pursuit and goal adjustment: a two-process framework. Develop Rev. 2002 ; 22 (2). 117-150 (Pubitemid 39659777)
45. Landes AM, Sperry SD, Strauss ME, Geldmacher DS. Apathy in Alzheimer's disease. J Am Geriatr Soc. 2001 ; 49 (12). 1700-1707 (Pubitemid 34007999)
46. Marin RS. Apathy: a neuropsychiatric syndrome. J Neuropsychiatry Clin Neurosci. 1991 ; 3 (3). 243-254
47. Okura T, Plassman BL, Steffens DC, Llewellyn DJ, Potter GG, Langa KM. Prevalence of neuropsychiatric symptoms and their association with functional limitations in older adults in the United States: the aging, demographics, and memory study. J Am Geriatr Soc. 2010 ; 58 (2). 330-337