Motivational symptoms of depression mask preclinical Alzheimer's disease in elderly subjects

Dementia and Geriatric Cognitive Disorders

Volumn 19, Issue 1, 2005, Pages 31-36

  Bartolini, Marco ^a,b   Coccia, Michela ^a   Luzzi, Simona ^a   Provinciali, Leandro ^a   Ceravolo, M Gabriella ^a  

^a UNIVERSITÀ POLITECNICA DELLE MARCHE   (Italy)

^b Azienda Ospedaliera Umberto I   (Italy)

Author keywords

Alzheimer's disease; Depression; Elderly population

Indexed keywords

ACADEMIC ACHIEVEMENT; AGE DISTRIBUTION; AGED; ALZHEIMER DISEASE; BECK DEPRESSION INVENTORY; COGNITION; CONTROLLED STUDY; DEPRESSION; DIAGNOSTIC AND STATISTICAL MANUAL OF MENTAL DISORDERS; ELDERLY CARE; FEMALE; FOLLOW UP; HUMAN; LOGISTIC REGRESSION ANALYSIS; MAJOR CLINICAL STUDY; MALE; MEMORY DISORDER; MOOD; MOTIVATION; MULTIVARIATE ANALYSIS; NEUROPSYCHOLOGICAL TEST; OUTPATIENT; PREDICTION; PRIORITY JOURNAL; REVIEW; SCORING SYSTEM; STATISTICAL SIGNIFICANCE; TASK PERFORMANCE;

AFFECT; AGED; ALZHEIMER DISEASE; DEPRESSIVE DISORDER; DIAGNOSIS, DIFFERENTIAL; FEMALE; FOLLOW-UP STUDIES; HUMANS; MALE; MIDDLE AGED; MOTIVATION; MULTIVARIATE ANALYSIS; NEUROPSYCHOLOGICAL TESTS; PERSONALITY INVENTORY; PROSPECTIVE STUDIES; PSYCHOMETRICS; SOMATOFORM DISORDERS;

EID: 10844274576     PISSN: 14208008     EISSN: None     Source Type: Journal    
DOI: 10.1159/000080968     Document Type: Review

References (25)

1. Rovner BW, Broadhead J, Spencer M, Carson K, Folstein MF: Depression and Alzheimer's disease. Am J Psychiatry 1989;146:350-353.
2. Migliorelli R, Teson A, Sabe L, Petracchi M, Leiguarda R, Starkstein SE: Prevalence and correlates of dysthymia and major depression among patients with Alzheimer's disease. Am J Psychiatry 1995;152:37-44.
3. Alexopoulos GS: The assessment and treatment of depressed-demented patients; in Nelson J (ed): Geriatric Psychopharmacology. New York, Decker, 1998, pp 223-244.
4. Tekin S, Cummings J: Depression in dementia. Neurologist 2001;7:252-259.
5. Raskind MA: The clinical interface of depression and dementia. J Clin Psychiatry 1998;59(suppl 10):9-12.
6. Kral VA, Emery OB: Long-term follow-up of depressive pseudodementia of the aged. Can J Psychiatry 1989;39:445-446.
7. Devandand DP, Sano M, Tang M-X, et al: Depressed mood and the incidence of Alzheimer's disease in the elderly living in the community. Arch Gen Psychiatry 1996;53:175-182.
8. Li YS, Meyer JS, Thornby J: Longitudinal follow-up of depressive symptoms among normal versus cognitively impaired elderly. Int J Geriatr Psychiatry 2001;16:718-727.
9. Berger AK, Fratiglioni L, Forsell Y, Winblad B, Backman L: The occurrence of depressive symptoms in the pre-clinical phase of AD: A population-based study. Neurology 1999;53:1998-2002.
10. Visser PJ, Verhey FRJ, Ponds RW, Kestera A, Jolles J: Distinction between pre-clinical Alzheimer's disease and depression. J Am Geriatr Soc 2000;48:479-484.
11. Emery VO, Oxman TE: Update on the dementia spectrum of depression. Am J Psychiatry 1992;149:305-317.
12. Rigaud AS, Traykov L, Caputo L, et al: Association of the apolipoprotein E epsilon 4 allele with late-onset-depression. Neuroepidemiology 2001;20:268-272.
13. Fabrigoule C, Rouch I, Taberly A, et al: Cognitive process in pre-clinical phase of dementia. Brain 1998;121:135-141.
14. McKhann G, Drachman D, Folstein M, Katzman R, Price D, Stadlan EM: Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology 1984;34:939-944.
15. Petersen RC, Smith GE, Waring SC, Ivnik RJ, Tangalos EG, Koknen E: Mild cognitive impairment: Clinical characteristics and outcome. Arch Neurol 1999;56:303-308.
16. Lezak M: Neuropsychological Assessment, ed 3. New York, Oxford Press, 1995.
17. Beck AT, Ward CH, Mendelson M, Mock JE, Erbaugh JK: An inventory for measuring depression. Arch Gen Psychiatry 1961;4:561-571.
18. American Psychiatric Association: Diagnostic and Statistic Manual of Mental Disorders, ed 3 revised. Washington, American Psychiatric Association, 1987.
19. Sackett DL, Richardson WS, Rosenberg W, Haynes RB: Evidence-Based Medicine. How to Practice and Teach EBM. Oxford, Churchill Livingstone, 1997.
20. Geerlings MI, Schmand B, Braam AW, Jonker C, Bouter LM, van Tilburg W: Depressive symptoms and risk of Alzheimer's disease in more highly educated older people. J Am Geriatric Soc 2000;48:1092-1097.
21. Cummings JL, Ross W, Absher J, Gornbein J, Hadjiaghai L: Depressive symptoms in Alzheimer's disease: Assessment and determinants. Alzheimer Dis Assoc Disord 1995;9:87-93.
22. Mega MS, Cummings JL, Fiorello T, et al: The spectrum of behavioural changes in Alzheimer's disease. Neurology 1996;46:130-135.
23. Jacobs DM, Sano M, Dooneief G, Marder K, Bell KL, Stern Y: Neuropsychological detection and characterization of pre-clinical Alzheimer's disease. Neurology 1995;45:957-962.
24. Baddeley AD: Working Memory. Oxford, Clarendon Press, 1986.
25. Kuzis G, Sabe L, Tiberti C, Dorremo F, Starkstein SE: Neuropsychological correlates of apathy and depression in patients with dementia. Neurology 1999;52:1403-1407.