The mouse small ubiquitin-like modifier-2 (SUMO-2) inhibits interleukin-12 (IL-12) production in mature dendritic cells by blocking the translocation of the p65 subunit of NFκB into the nucleus

Molecular Immunology

Volumn 48, Issue 15-16, 2011, Pages 2189-2197

  Kim, Eun Mi ^a   Lee, Han Hyoung ^a   Kim, Sang Hoon ^a   Son, Young Ok ^b   Lee, Suk Jun ^a   Han, Jihye ^a   Bae, Joonbeom ^a   Kim, Sang Joon ^c   Park, Chung Gyu ^c   Park, Yongsoo ^d   Hwang, Kwang Woo ^e   Chun, Taehoon ^a  

^a Korea University   (South Korea)

^b UNIVERSITY OF KENTUCKY   (United States)

^c Seoul National University   (South Korea)

^d Hanyang University   (South Korea)

^e Chung Ang University   (South Korea)

Author keywords

Dendritic cells; IL 12; NF B; Post translational modification; Sumoylation

Indexed keywords

ANTIGEN; B7 ANTIGEN; CD86 ANTIGEN; I KAPPA B ALPHA; INTERLEUKIN 12; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; SUMO 2 PROTEIN; TRANSCRIPTION FACTOR RELA;

ANIMAL CELL; ARTICLE; CD4+ T LYMPHOCYTE; CELL MATURATION; CELL NUCLEUS; CONTROLLED STUDY; CYTOKINE PRODUCTION; DENDRITIC CELL; ENZYME ACTIVITY; IN VITRO STUDY; MOLECULAR EVOLUTION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; POLARIZATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN TRANSPORT; REGULATORY MECHANISM; TH2 CELL;

ANIMALS; ANTIGEN PRESENTATION; BLOTTING, WESTERN; CELL DIFFERENTIATION; CELL NUCLEUS; CELL SEPARATION; CHROMATIN IMMUNOPRECIPITATION; DENDRITIC CELLS; ELECTROPHORETIC MOBILITY SHIFT ASSAY; FLOW CYTOMETRY; I-KAPPA B PROTEINS; INTERLEUKIN-12; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED C57BL; MICROSCOPY, CONFOCAL; PHAGOCYTOSIS; PROTEIN TRANSPORT; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SMALL UBIQUITIN-RELATED MODIFIER PROTEINS; SUMOYLATION; TH2 CELLS; TRANSCRIPTION FACTOR RELA;

EID: 80051925139     PISSN: 01615890     EISSN: 18729142     Source Type: Journal    
DOI: 10.1016/j.molimm.2011.05.002     Document Type: Article

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