A new growth factor controlled drug release system to promote healing of bone fractures: Nanospheres of recombinant human bone morphogenetic-2 and polylactic acid

Journal of Nanoscience and Nanotechnology

Volumn 11, Issue 4, 2011, Pages 3107-3114

  Chen, Lin ^a   Liu, Lei ^a   Li, Cai ^a   Tan, Yinghui ^b   Zhang, Gang ^b  

^a SICHUAN UNIVERSITY   (China)

^b THIRD MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Bone Morphogenetic Protein 2 (BMP 2); Controlled Release; Nanospheres; Polylactide

Indexed keywords

BONE MORPHOGENETIC PROTEIN-2; CONTROLLED DRUG RELEASE SYSTEMS; CONTROLLED RELEASE; ENCAPSULATION EFFICIENCY; ENZYME-LINKED IMMUNOSORBENT ASSAY METHODS; IMMUNOHISTOCHEMICAL ANALYSIS; POLY LACTIDE; VASCULAR ENDOTHELIAL GROWTH FACTOR;

BIOACTIVITY; DRUG PRODUCTS; EMULSIFICATION; ENCAPSULATION; FLUORESCENCE; FRACTURE; MULTILAYER FILMS; NANOSPHERES; PARTICLE SIZE ANALYSIS;

BONE;

BMP2 PROTEIN, HUMAN; BONE MORPHOGENETIC PROTEIN 2; LACTIC ACID; NANOCAPSULE; POLYLACTIC ACID; POLYMER; RECOMBINANT PROTEIN; SIGNAL PEPTIDE;

ARTICLE; CELL LINE; CHEMISTRY; DELAYED RELEASE FORMULATION; DRUG EFFECT; FRACTURE; FRACTURE HEALING; GENETICS; HUMAN; OSTEOBLAST; PHYSIOLOGY;

BONE MORPHOGENETIC PROTEIN 2; CELL LINE; DELAYED-ACTION PREPARATIONS; FRACTURE HEALING; FRACTURES, BONE; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; LACTIC ACID; NANOCAPSULES; OSTEOBLASTS; POLYMERS; RECOMBINANT PROTEINS;

EID: 80051917192     PISSN: 15334880     EISSN: 15334899     Source Type: Journal    
DOI: 10.1166/jnn.2011.3820     Document Type: Article

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