Increasing concentrations of prothrombin complex concentrate induce disseminated intravascular coagulation in a pig model of coagulopathy with blunt liver injury

Blood

Volumn 118, Issue 7, 2011, Pages 1943-1951

  Grottke, Oliver ^a   Braunschweig, Till ^a   Spronk, Henri M H ^b   Esch, Stephanie ^a   Rieg, Annette D ^a   Van Oerle, Rene ^b   Ten Cate, Hugo ^b   Fitzner, Christina ^a   Tolba, Rene ^a   Rossaint, Rolf ^a  

^a UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

^b MAASTRICHT UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

COFACT; HETASTARCH; PROTHROMBIN COMPLEX; RINGER LACTATE SOLUTION; SANQUIN; THROMBIN; UNCLASSIFIED DRUG;

ANALYTIC METHOD; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLEEDING; BLOOD CLOTTING DISORDER; BLOOD VOLUME; BLUNT TRAUMA; CONTROLLED STUDY; DISSEMINATED INTRAVASCULAR CLOTTING; DOSE RESPONSE; DRUG SAFETY; ERYTHROCYTE TRANSFUSION; LIVER INJURY; MALE; NONHUMAN; PRIORITY JOURNAL; RISK BENEFIT ANALYSIS; SURVIVAL; SWINE; THROMBOELASTOMETRY; THROMBOEMBOLISM; TREATMENT OUTCOME;

EID: 80051887979     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2011-03-343046     Document Type: Article

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