-
1
-
-
68049103342
-
Defnition, classification and epidemiology of pulmonary arterial hypertension
-
Hoeper M. Defnition, classification and epidemiology of pulmonary arterial hypertension. Semin Respir Crit Care Med. 2009;30:369-375.
-
(2009)
Semin Respir Crit Care Med
, vol.30
, pp. 369-375
-
-
Hoeper, M.1
-
2
-
-
0025837793
-
Survival in patients with primary pulmonary hypertension
-
D'Alonzo GF, Barst RJ, Ayres SM, et al. Survival in patients with primary pulmonary hypertension. Ann Intern Med. 1991;115:343-349.
-
(1991)
Ann Intern Med
, vol.115
, pp. 343-349
-
-
D'alonzo, G.F.1
Barst, R.J.2
Ayres, S.M.3
-
3
-
-
77951961897
-
Contemporary survival in patients with pulmonary arterial hypertension: A reappraisal of the NIH risk stratifcation equation
-
Thenappan T, Shah S, Rich S, Tian L, Archer S, Gomberg-Maitland M. Contemporary survival in patients with pulmonary arterial hypertension: A reappraisal of the NIH risk stratifcation equation. Eur Respir J. 2010;35:1079-1087.
-
(2010)
Eur Respir J
, vol.35
, pp. 1079-1087
-
-
Thenappan, T.1
Shah, S.2
Rich, S.3
Tian, L.4
Archer, S.5
Gomberg-Maitland, M.6
-
4
-
-
33646269035
-
Pulmonary arterial hypertension in France: Results from a national registry
-
Humbert M, Sitbon O, Chaouat A, et al. Pulmonary arterial hypertension in France: Results from a national registry. Am J Respir Crit Care Med. 2006;173:1023-1030.
-
(2006)
Am J Respir Crit Care Med
, vol.173
, pp. 1023-1030
-
-
Humbert, M.1
Sitbon, O.2
Chaouat, A.3
-
5
-
-
34447546600
-
An epi-demiological study of pulmonary arterial hypertension
-
Peacock A, Murphy N, McMurray J, Caballero L, Stewart S. An epi-demiological study of pulmonary arterial hypertension. Eur Respir J. 2007;30:104-109.
-
(2007)
Eur Respir J
, vol.30
, pp. 104-109
-
-
Peacock, A.1
Murphy, N.2
McMurray, J.3
Caballero, L.4
Stewart, S.5
-
6
-
-
37549033243
-
A USA-based registry for pulmonary arterial hypertension: 1982-2006
-
Thenappan T, Shah S, Rich S, Gomberg-Maitland M. A USA-based registry for pulmonary arterial hypertension: 1982-2006. Eur Respir J. 2007;30:1103-1110.
-
(2007)
Eur Respir J
, vol.30
, pp. 1103-1110
-
-
Thenappan, T.1
Shah, S.2
Rich, S.3
Gomberg-Maitland, M.4
-
7
-
-
67649579669
-
Updated clinical classifcation of pulmonary hypertension
-
Simmoneau G, Robbins I, Beghetti M, et al. Updated clinical classifcation of pulmonary hypertension. J Am Coll Cardiol. 2009;54:S43-S54.
-
(2009)
J Am Coll Cardiol
, vol.54
-
-
Simmoneau, G.1
Robbins, I.2
Beghetti, M.3
-
8
-
-
76749135710
-
Pulmonary arterial hypertension - baseline characteristics from the REVEAL registry
-
Badesch D, Raskob G, Elliott C, et al. Pulmonary arterial hypertension - baseline characteristics from the REVEAL registry. Chest. 2010;137:376-387.
-
(2010)
Chest
, vol.137
, pp. 376-387
-
-
Badesch, D.1
Raskob, G.2
Elliott, C.3
-
9
-
-
66549127501
-
ACCF/AHA 2009 expert consensus document on pulmonary hypertension
-
McLaughlin V, Archer S, Badesch D, et al. ACCF/AHA 2009 expert consensus document on pulmonary hypertension. Circulation. 2009; 119:2250-2294.
-
(2009)
Circulation
, vol.119
, pp. 2250-2294
-
-
McLaughlin, V.1
Archer, S.2
Badesch, D.3
-
10
-
-
70349634397
-
Guidelines for the diagnosis and treatment of pulmonary hypertension
-
Galie N, Hoeper M, Humbert M, et al. Guidelines for the diagnosis and treatment of pulmonary hypertension. Eur Respir J. 2009;34: 1219-1263.
-
(2009)
Eur Respir J
, vol.34
, pp. 1219-1263
-
-
Galie, N.1
Hoeper, M.2
Humbert, M.3
-
11
-
-
5344233478
-
Pulmonary arterial hypertension
-
Farber H, Loscalzo J. Pulmonary arterial hypertension. N Engl J Med. 2004;351:1655-1665.
-
(2004)
N Engl J Med
, vol.351
, pp. 1655-1665
-
-
Farber, H.1
Loscalzo, J.2
-
12
-
-
0026628265
-
An imbalance between the excretion of thromboxane and prostacyclin metabolites in pulmonary hypertension
-
Christman B, McPherson C, Newman J, et al. An imbalance between the excretion of thromboxane and prostacyclin metabolites in pulmonary hypertension. N Engl J Med. 1992;327:70-75.
-
(1992)
N Engl J Med
, vol.327
, pp. 70-75
-
-
Christman, B.1
McPherson, C.2
Newman, J.3
-
13
-
-
0027324745
-
Expression of endothe-lin-1 in the lungs of patients with pulmonary hypertension
-
Giaid A, Yanagisawa M, Langleben D, et al. Expression of endothe-lin-1 in the lungs of patients with pulmonary hypertension. N Engl J Med. 1993;328:1732-1739.
-
(1993)
N Engl J Med
, vol.328
, pp. 1732-1739
-
-
Giaid, A.1
Yanagisawa, M.2
Langleben, D.3
-
14
-
-
0026034713
-
Increased plasma endothelin-1 in pulmonary hypertension: Marker or mediator of disease
-
Stewart D, Levy R, Cernacek P, Langleben D. Increased plasma endothelin-1 in pulmonary hypertension: Marker or mediator of disease? Ann Intern Med. 1991;114:464-469.
-
(1991)
Ann Intern Med
, vol.114
, pp. 464-469
-
-
Stewart, D.1
Levy, R.2
Cernacek, P.3
Langleben, D.4
-
15
-
-
0033032949
-
Prostacyclin synthase expression is decreased in lungs from patients with severe pulmonary hypertension
-
Tuder R, Cool C, Geraci M, et al. Prostacyclin synthase expression is decreased in lungs from patients with severe pulmonary hypertension. Am J Respir Crit Care Med. 1999;159:1925-1932.
-
(1999)
Am J Respir Crit Care Med
, vol.159
, pp. 1925-1932
-
-
Tuder, R.1
Cool, C.2
Geraci, M.3
-
16
-
-
0023615359
-
Primary pulmonary hypertension - a national prospective study
-
Rich S, Dantzker D, Ayres S, et al. Primary pulmonary hypertension - a national prospective study. Ann Intern Med. 1987;107:216-223.
-
(1987)
Ann Intern Med
, vol.107
, pp. 216-223
-
-
Rich, S.1
Dantzker, D.2
Ayres, S.3
-
17
-
-
3142692425
-
Screening, early detection and diagnosis of pulmonary arterial hypertension
-
McGoon M, Gutterman D, Steen V, et al. Screening, early detection and diagnosis of pulmonary arterial hypertension. Chest. 2004;126 Suppl 1: 14S-34S.
-
(2004)
Chest
, vol.126
, Issue.SUPPL. 1
-
-
McGoon, M.1
Gutterman, D.2
Steen, V.3
-
18
-
-
0035808004
-
Clinical correlates and reference intervals for pulmonary artery systolic pressure among echocardiographically normal subjects
-
McQuillan B, Picard M, Leavitt M, Weyman A. Clinical correlates and reference intervals for pulmonary artery systolic pressure among echocardiographically normal subjects. Circulation. 2001;104: 2797-2802.
-
(2001)
Circulation
, vol.104
, pp. 2797-2802
-
-
McQuillan, B.1
Picard, M.2
Leavitt, M.3
Weyman, A.4
-
19
-
-
0014964972
-
Catheterization of the heart in man with use of a fow-directed balloon-tipped catheter
-
Swan H, Ganz W, Forrester J, Marcu H, Diamond G, Chonette D. Catheterization of the heart in man with use of a fow-directed balloon-tipped catheter. N Engl J Med. 1970;283:447-451.
-
(1970)
N Engl J Med
, vol.283
, pp. 447-451
-
-
Swan, H.1
Ganz, W.2
Forrester, J.3
Marcu, H.4
Diamond, G.5
Chonette, D.6
-
20
-
-
0031747446
-
Outcome of pulmonary vascular disease in pregnancy: A systematic overview from 1978 through 1996
-
Weiss B, Zemp L, Seifert B, Hess O. Outcome of pulmonary vascular disease in pregnancy: A systematic overview from 1978 through 1996. J Am Coll Cardiol. 1998;31:1650-1657.
-
(1998)
J Am Coll Cardiol
, vol.31
, pp. 1650-1657
-
-
Weiss, B.1
Zemp, L.2
Seifert, B.3
Hess, O.4
-
21
-
-
0026632785
-
The effect of high doses of calcium-channel blockers on survival in primary pulmonary hypertension
-
Rich S, Kaufman E, Levy P. The effect of high doses of calcium-channel blockers on survival in primary pulmonary hypertension. N Engl J Med. 1992;327:76-81.
-
(1992)
N Engl J Med
, vol.327
, pp. 76-81
-
-
Rich, S.1
Kaufman, E.2
Levy, P.3
-
22
-
-
0030813510
-
The effect of anticoagulant therapy in primary and anorectic drug-induced pulmonary hypertension
-
Frank H, Mlczoch J, Huber K, Schuster E, Gurtner H, Kneussl M. The effect of anticoagulant therapy in primary and anorectic drug-induced pulmonary hypertension. Chest. 1997;112:714-721.
-
(1997)
Chest
, vol.112
, pp. 714-721
-
-
Frank, H.1
Mlczoch, J.2
Huber, K.3
Schuster, E.4
Gurtner, H.5
Kneussl, M.6
-
23
-
-
0021193273
-
Primary pulmonary hypertension: Natural history and the importance of thrombosis
-
Fuster V, Steele P, Edwards W, Gersh B, McGoon M, Frye R. Primary pulmonary hypertension: Natural history and the importance of thrombosis. Circulation. 1984;70:580-587.
-
(1984)
Circulation
, vol.70
, pp. 580-587
-
-
Fuster, V.1
Steele, P.2
Edwards, W.3
Gersh, B.4
McGoon, M.5
Frye, R.6
-
24
-
-
0031719459
-
The short-term effects of digoxin in patients with right ventricular dysfunction from pulmonary hypertension
-
Rich S, Seidlitz M, Dodin E, et al. The short-term effects of digoxin in patients with right ventricular dysfunction from pulmonary hypertension. Chest. 1998;114:787-792.
-
(1998)
Chest
, vol.114
, pp. 787-792
-
-
Rich, S.1
Seidlitz, M.2
Dodin, E.3
-
25
-
-
20544448927
-
Long-term response to calcium channel blockers in idiopathic pulmonary arterial hypertension
-
Sitbon O, Humbert M, Jais X, et al. Long-term response to calcium channel blockers in idiopathic pulmonary arterial hypertension. Circulation. 2005;111:3105-3111.
-
(2005)
Circulation
, vol.111
, pp. 3105-3111
-
-
Sitbon, O.1
Humbert, M.2
Jais, X.3
-
26
-
-
0022067275
-
Characterization of a coronary vasoconstrictor produced by cultured endothelial cells
-
Hickey K, Rubanyi G, Paul R, Highsmith R. Characterization of a coronary vasoconstrictor produced by cultured endothelial cells. Am J Physiol. 1985;248:C550-C556.
-
(1985)
Am J Physiol
, vol.248
-
-
Hickey, K.1
Rubanyi, G.2
Paul, R.3
Highsmith, R.4
-
27
-
-
0023859136
-
A novel potent vasoconstrictor peptide produced by vascular endothelial cells
-
Yanagisawa M, Kurihara H, Kimura S, et al. A novel potent vasoconstrictor peptide produced by vascular endothelial cells. Nature. 1988; 332:411-415.
-
(1988)
Nature
, vol.332
, pp. 411-415
-
-
Yanagisawa, M.1
Kurihara, H.2
Kimura, S.3
-
28
-
-
0035040924
-
Endothelin system: The double-edged sword in health and disease
-
Kedzierski R, Yanagisawa M. Endothelin system: The double-edged sword in health and disease. Annu Rev Pharmacol Toxicol. 2001;41:851-876.
-
(2001)
Annu Rev Pharmacol Toxicol
, vol.41
, pp. 851-876
-
-
Kedzierski, R.1
Yanagisawa, M.2
-
29
-
-
0035171979
-
Big endothelin-1 and endothelin-1 plasma levels are correlated with the severity of primary pulmonary hypertension
-
Rubens C, Ewert R, Halank M, et al. Big endothelin-1 and endothelin-1 plasma levels are correlated with the severity of primary pulmonary hypertension. Chest. 2001;120:1562-1569.
-
(2001)
Chest
, vol.120
, pp. 1562-1569
-
-
Rubens, C.1
Ewert, R.2
Halank, M.3
-
30
-
-
70049091002
-
Endothelin receptor antagonists for pulmonary arterial hypertension
-
Liu C, Chen J, Gao Y, Deng B, Liu K. Endothelin receptor antagonists for pulmonary arterial hypertension. Cochrane Database Syst Rev. 2009;3:CD004434.
-
(2009)
Cochrane Database Syst Rev
, vol.3
-
-
Liu, C.1
Chen, J.2
Gao, Y.3
Deng, B.4
Liu, K.5
-
31
-
-
0035818316
-
Effects of the dual endothelin-receptor antagonist bosentan in patients with pulmonary hypertension: A randomised placebo controlled study
-
Channick R, Simonneau G, Sitbon O, et al. Effects of the dual endothelin-receptor antagonist bosentan in patients with pulmonary hypertension: A randomised placebo controlled study. Lancet. 2001; 358:1119-1123.
-
(2001)
Lancet
, vol.358
, pp. 1119-1123
-
-
Channick, R.1
Simonneau, G.2
Sitbon, O.3
-
32
-
-
0037149718
-
Bosentan therapy for pulmonary arterial hypertension
-
Rubin L, Badesch D, Barst R, et al. Bosentan therapy for pulmonary arterial hypertension. N Engl J Med. 2002;346:896-903.
-
(2002)
N Engl J Med
, vol.346
, pp. 896-903
-
-
Rubin, L.1
Badesch, D.2
Barst, R.3
-
33
-
-
13844280943
-
Survival with first-line bosentan in patients with primary pulmonary hypertension
-
McLaughlin V, Sitbon O, Badesch B, et al. Survival with first-line bosentan in patients with primary pulmonary hypertension. Eur Respir J. 2005;25:244-249.
-
(2005)
Eur Respir J
, vol.25
, pp. 244-249
-
-
McLaughlin, V.1
Sitbon, O.2
Badesch, B.3
-
34
-
-
33645243403
-
Long-term outcome with frst-line bosentan therapy in idiopathic pulmonary arterial hypertension
-
Provencher S, Sitbon O, Humbert M, Cabrol S, Jais X, Simonneau G. Long-term outcome with frst-line bosentan therapy in idiopathic pulmonary arterial hypertension. Eur Heart J. 2006;27:589-595.
-
(2006)
Eur Heart J
, vol.27
, pp. 589-595
-
-
Provencher, S.1
Sitbon, O.2
Humbert, M.3
Cabrol, S.4
Jais, X.5
Simonneau, G.6
-
35
-
-
45249119855
-
Treatment of patients with mildly symptomatic pulmonary arterial hypertension with bosentan (EARLY study): A double-blind, randomised controlled trial
-
Galie N, Rubin L, Hal-Hiti P, et al. Treatment of patients with mildly symptomatic pulmonary arterial hypertension with bosentan (EARLY study): A double-blind, randomised controlled trial. Lancet. 2008;371:2093-2100.
-
(2008)
Lancet
, vol.371
, pp. 2093-2100
-
-
Galie, N.1
Rubin, L.2
Hal-Hiti, P.3
-
36
-
-
0030943903
-
Discovery of TBC11251, a potent, long acting, orally active endothelin receptor-a selective antagonist
-
Wu C, Chan M, Stavros F, et al. Discovery of TBC11251, a potent, long acting, orally active endothelin receptor-a selective antagonist. J Med Chem. 1997;40:1690-1697.
-
(1997)
J Med Chem
, vol.40
, pp. 1690-1697
-
-
Wu, C.1
Chan, M.2
Stavros, F.3
-
37
-
-
10744230817
-
Sitaxsentan therapy for pulmonary arterial hypertension
-
Barst R, Langleben D, Frost A, et al. Sitaxsentan therapy for pulmonary arterial hypertension. Am J Respir Crit Care Med. 2004;169: 441-447.
-
(2004)
Am J Respir Crit Care Med
, vol.169
, pp. 441-447
-
-
Barst, R.1
Langleben, D.2
Frost, A.3
-
38
-
-
33646255654
-
Treatment of pulmonary arterial hypertension with the selective endothelin-a receptor antagonist sitaxsentan
-
Barst R, Langleben D, Badesch D, et al. Treatment of pulmonary arterial hypertension with the selective endothelin-a receptor antagonist sitaxsentan. J Am Coll Cardiol. 2006;47:2049-2056.
-
(2006)
J Am Coll Cardiol
, vol.47
, pp. 2049-2056
-
-
Barst, R.1
Langleben, D.2
Badesch, D.3
-
39
-
-
6344240798
-
Sustained symptomatic, functional, and hemodynamic beneft with the selective endothelin-a receptor antagonist, sitaxsentan, in patients with pulmonary arterial hypertension
-
Langleben D, Hirsch A, Shalit E, Lezenko L, Barst R. Sustained symptomatic, functional, and hemodynamic beneft with the selective endothelin-a receptor antagonist, sitaxsentan, in patients with pulmonary arterial hypertension. Chest. 2004;126:1377-1381.
-
(2004)
Chest
, vol.126
, pp. 1377-1381
-
-
Langleben, D.1
Hirsch, A.2
Shalit, E.3
Lezenko, L.4
Barst, R.5
-
40
-
-
22844436819
-
Ambrisentan therapy for pulmonary arterial hypertension
-
Galie N, Badesch D, Oudiz R, et al. Ambrisentan therapy for pulmonary arterial hypertension. J Am Coll Cardiol. 2005;46:529-535.
-
(2005)
J Am Coll Cardiol
, vol.46
, pp. 529-535
-
-
Galie, N.1
Badesch, D.2
Oudiz, R.3
-
41
-
-
46449124591
-
Ambrisentan for the treatment of pulmonary arterial hypertension
-
Galie N, Olschewski H, Oudiz R, et al. Ambrisentan for the treatment of pulmonary arterial hypertension. Circulation. 2008;117:3010-3019.
-
(2008)
Circulation
, vol.117
, pp. 3010-3019
-
-
Galie, N.1
Olschewski, H.2
Oudiz, R.3
-
42
-
-
84860285994
-
Phosphodiesterase type 5 inhibitors for pulmonary arterial hypertension
-
Archer S, Michelakis E. Phosphodiesterase type 5 inhibitors for pulmonary arterial hypertension. N Engl J Med. 2009;361:1864-1871.
-
(2009)
N Engl J Med
, vol.361
, pp. 1864-1871
-
-
Archer, S.1
Michelakis, E.2
-
43
-
-
0029055964
-
Reduced expression of endothelial nitric oxide synthase in the lungs of patients with pulmonary hypertension
-
Giaid A, Saleh D. Reduced expression of endothelial nitric oxide synthase in the lungs of patients with pulmonary hypertension. N Engl J Med. 1995;333:214-221.
-
(1995)
N Engl J Med
, vol.333
, pp. 214-221
-
-
Giaid, A.1
Saleh, D.2
-
44
-
-
12244282450
-
Increased expression of the cGMP-inhibited cAMP-specific (PDE3) and cGMP binding cGMP-specifc (PDE5) phosphodiesterases in models of pulmonary hypertension
-
Murray F, MacLean M, Pyne N. Increased expression of the cGMP-inhibited cAMP-specific (PDE3) and cGMP binding cGMP-specifc (PDE5) phosphodiesterases in models of pulmonary hypertension. Br J Pharmacol. 2002;137:1187-1194.
-
(2002)
Br J Pharmacol
, vol.137
, pp. 1187-1194
-
-
Murray, F.1
Maclean, M.2
Pyne, N.3
-
45
-
-
26444534291
-
Sildenafl citrate therapy for pulmonary arterial hypertension
-
Galie N, Ghofrani H, Torbicki A, et al. Sildenafl citrate therapy for pulmonary arterial hypertension. N Engl J Med. 2005;353: 2148-2157.
-
(2005)
N Engl J Med
, vol.353
, pp. 2148-2157
-
-
Galie, N.1
Ghofrani, H.2
Torbicki, A.3
-
46
-
-
38349081419
-
Sildenafl improves health-related quality of life in patients with pulmonary arterial hypertension
-
Pepke-Zaba J, Gilbert C, Collings L, Brown M. Sildenafl improves health-related quality of life in patients with pulmonary arterial hypertension. Chest. 2008;133:183-189.
-
(2008)
Chest
, vol.133
, pp. 183-189
-
-
Pepke-Zaba, J.1
Gilbert, C.2
Collings, L.3
Brown, M.4
-
47
-
-
67649523052
-
Tadalafil therapy for pulmonary arterial hypertension
-
Galie N, Brundage B, Ghofrani H, et al. Tadalafil therapy for pulmonary arterial hypertension. Circulation. 2009;119:2894-2903.
-
(2009)
Circulation
, vol.119
, pp. 2894-2903
-
-
Galie, N.1
Brundage, B.2
Ghofrani, H.3
-
48
-
-
0344474511
-
Tolerance development to antimitogenic actions of prostacyclin but not of prostaglandin E1 in coronary artery smooth muscle cells
-
Zucker T, Bunisch D, Hasse A, Grosser T, Weber A, Schror K. Tolerance development to antimitogenic actions of prostacyclin but not of prostaglandin E1 in coronary artery smooth muscle cells. Eur J Pharmacol. 1998;345:213-220.
-
(1998)
Eur J Pharmacol
, vol.345
, pp. 213-220
-
-
Zucker, T.1
Bunisch, D.2
Hasse, A.3
Grosser, T.4
Weber, A.5
Schror, K.6
-
49
-
-
0037134011
-
Role of prostacyclin in the cardiovascular response to thromboxane A2
-
Cheng Y, Austin S, Rocca B, et al. Role of prostacyclin in the cardiovascular response to thromboxane A2. Science. 2002;296:539-541.
-
(2002)
Science
, vol.296
, pp. 539-541
-
-
Cheng, Y.1
Austin, S.2
Rocca, B.3
-
50
-
-
3242786431
-
Pharmacokinetics and steady-state bioequivalence of treprostinil sodium (Remodulin) administered by the intravenous and subcutaneous route to normal volunteers
-
Laliberte K, Arneson C, Jeffs R, Hunt T, Wade M. Pharmacokinetics and steady-state bioequivalence of treprostinil sodium (Remodulin) administered by the intravenous and subcutaneous route to normal volunteers. J Cardiovasc Pharmacol. 2004;44:209-214.
-
(2004)
J Cardiovasc Pharmacol
, vol.44
, pp. 209-214
-
-
Laliberte, K.1
Arneson, C.2
Jeffs, R.3
Hunt, T.4
Wade, M.5
-
51
-
-
0037126044
-
Survival in primary pulmonary hypertension: The impact of epoprostenol therapy
-
McLaughlin V, Shilington A, Rich S. Survival in primary pulmonary hypertension: The impact of epoprostenol therapy. Circulation. 2002; 106:1477-1482.
-
(2002)
Circulation
, vol.106
, pp. 1477-1482
-
-
McLaughlin, V.1
Shilington, A.2
Rich, S.3
-
52
-
-
0037151645
-
Long-term intravenous epoprostenol infusion in primary pulmonary hypertension
-
Sitbon O, Humbert M, Nunes H, et al. Long-term intravenous epoprostenol infusion in primary pulmonary hypertension. J Am Coll Cardiol. 2002;40:780-788.
-
(2002)
J Am Coll Cardiol
, vol.40
, pp. 780-788
-
-
Sitbon, O.1
Humbert, M.2
Nunes, H.3
-
53
-
-
0030031888
-
A comparison of continuous intravenous epoprostenol (prostacyclin) with conventional therapy for primary pulmonary hypertension
-
Barst R, Rubin L, Long W, et al. A comparison of continuous intravenous epoprostenol (prostacyclin) with conventional therapy for primary pulmonary hypertension. N Engl J Med. 1996;334:296-301.
-
(1996)
N Engl J Med
, vol.334
, pp. 296-301
-
-
Barst, R.1
Rubin, L.2
Long, W.3
-
54
-
-
17144452827
-
Continuous intravenous epo-prostenol for pulmonary hypertension due to the scleroderma spectrum of disease
-
Badesch D, Tapson V, McGoon M, et al. Continuous intravenous epo-prostenol for pulmonary hypertension due to the scleroderma spectrum of disease. Ann Intern Med. 2000;132:425-434.
-
(2000)
Ann Intern Med
, vol.132
, pp. 425-434
-
-
Badesch, D.1
Tapson, V.2
McGoon, M.3
-
55
-
-
0033679134
-
Epoprostenol (prostacyclin) therapy in HIV-associated pulmonary hypertension
-
Aguilar R, Farber H. Epoprostenol (prostacyclin) therapy in HIV-associated pulmonary hypertension. Am J Respir Crit Care Med. 2000; 162:1846-1850.
-
(2000)
Am J Respir Crit Care Med
, vol.162
, pp. 1846-1850
-
-
Aguilar, R.1
Farber, H.2
-
56
-
-
0032570541
-
Successful use of chronic epoprostenol as a bridge to liver transplantation in severe portopulmonary hypertension
-
Plotkin J, Kuo P, Rubin L, et al. Successful use of chronic epoprostenol as a bridge to liver transplantation in severe portopulmonary hypertension. Transplantation. 1998;4:457-459.
-
(1998)
Transplantation
, vol.4
, pp. 457-459
-
-
Plotkin, J.1
Kuo, P.2
Rubin, L.3
-
57
-
-
0034893886
-
Liver transplantation in patients with severe portopulmonary hypertension treated with preoperative chronic intravenous epoprostenol
-
Tan H, Markowitz J, Montgomery R, et al. Liver transplantation in patients with severe portopulmonary hypertension treated with preoperative chronic intravenous epoprostenol. Liver Transpl. 2001;7:745-749.
-
(2001)
Liver Transpl
, vol.7
, pp. 745-749
-
-
Tan, H.1
Markowitz, J.2
Montgomery, R.3
-
58
-
-
0033551155
-
Long-term prostacyclin for pulmonary hypertension with associated congenital heart defects
-
Rosenzweig E, Kerstein D, Barst R. Long-term prostacyclin for pulmonary hypertension with associated congenital heart defects. Circulation. 1999;99:1858-1865.
-
(1999)
Circulation
, vol.99
, pp. 1858-1865
-
-
Rosenzweig, E.1
Kerstein, D.2
Barst, R.3
-
60
-
-
0037086133
-
Continuous subcutaneous infusion of treprostinil, a prostacyclin analogue, in patients with pulmonary arterial hypertension
-
Simonneau G, Barst R, Galie N, et al. Continuous subcutaneous infusion of treprostinil, a prostacyclin analogue, in patients with pulmonary arterial hypertension. Am J Respir Crit Care Med. 2002;165:800-804.
-
(2002)
Am J Respir Crit Care Med
, vol.165
, pp. 800-804
-
-
Simonneau, G.1
Barst, R.2
Galie, N.3
-
61
-
-
33745172176
-
Efficacy of long-term subcutaneous treprostinil sodium therapy in pulmonary hypertension
-
Lang I, Gomez-Sanchez M, Kneussl M, et al. Efficacy of long-term subcutaneous treprostinil sodium therapy in pulmonary hypertension. Chest. 2006;129:1636-1643.
-
(2006)
Chest
, vol.129
, pp. 1636-1643
-
-
Lang, I.1
Gomez-Sanchez, M.2
Kneussl, M.3
-
62
-
-
33845360014
-
Long-term outcome in pulmonary arterial hypertension patients treated with subcutaneous treprostinil
-
Barst R, Galie N, Simonneau G, Jeffs R, Arneson C, Rubin L. Long-term outcome in pulmonary arterial hypertension patients treated with subcutaneous treprostinil. Eur Heart J. 2006;28:1195-1203.
-
(2006)
Eur Heart J
, vol.28
, pp. 1195-1203
-
-
Barst, R.1
Galie, N.2
Simonneau, G.3
Jeffs, R.4
Arneson, C.5
Rubin, L.6
-
63
-
-
33645119109
-
Safety and effcacy of IV treprostinil for pulmonary arterial hypertension
-
Tapson V, Gomberg-Maitland M, McLaughlin V, et al. Safety and effcacy of IV treprostinil for pulmonary arterial hypertension. Chest. 2006;129:683-688.
-
(2006)
Chest
, vol.129
, pp. 683-688
-
-
Tapson, V.1
Gomberg-Maitland, M.2
McLaughlin, V.3
-
64
-
-
67449108485
-
Inhaled iloprost for the control of pulmonary hypertension
-
Krug S, Sablotzki A, Hammerschmidt S, Wirtz H, Seyfarth H. Inhaled iloprost for the control of pulmonary hypertension. Vasc Health Risk Manag. 2009;5:465-474.
-
(2009)
Vasc Health Risk Manag
, vol.5
, pp. 465-474
-
-
Krug, S.1
Sablotzki, A.2
Hammerschmidt, S.3
Wirtz, H.4
Seyfarth, H.5
-
65
-
-
0029993602
-
Aerosolized prostacyclin and iloprost in severe pulmonary hypertension
-
Olschewski H, Walmrath D, Schermuly R, Ghofrani A, Grimminger F, Seeger W. Aerosolized prostacyclin and iloprost in severe pulmonary hypertension. Ann Intern Med. 1996;124:820-824.
-
(1996)
Ann Intern Med
, vol.124
, pp. 820-824
-
-
Olschewski, H.1
Walmrath, D.2
Schermuly, R.3
Ghofrani, A.4
Grimminger, F.5
Seeger, W.6
-
66
-
-
0034696634
-
Inhaled iloprost to treat severe pulmonary hypertension
-
Olschewski H, Ghofrani A, Schmehl T, et al. Inhaled iloprost to treat severe pulmonary hypertension. Ann Intern Med. 2000;132:435-443.
-
(2000)
Ann Intern Med
, vol.132
, pp. 435-443
-
-
Olschewski, H.1
Ghofrani, A.2
Schmehl, T.3
-
67
-
-
0036682273
-
Inhaled iloprost for severe pulmonary hypertension
-
Olschewski H, Simonneau G, Galie N, et al. Inhaled iloprost for severe pulmonary hypertension. N Engl J Med. 2002;347:322-329.
-
(2002)
N Engl J Med
, vol.347
, pp. 322-329
-
-
Olschewski, H.1
Simonneau, G.2
Galie, N.3
-
68
-
-
0034702248
-
Long-term treatment of primary pulmonary hypertension with aerosolized iloprost, a prostacyclin analogue
-
Hoeper M, Schwarze M, Ehlerding S, et al. Long-term treatment of primary pulmonary hypertension with aerosolized iloprost, a prostacyclin analogue. N Engl J Med. 2000;342:1866-1870.
-
(2000)
N Engl J Med
, vol.342
, pp. 1866-1870
-
-
Hoeper, M.1
Schwarze, M.2
Ehlerding, S.3
-
69
-
-
21544449424
-
Clinical efficacy and survival with first-line inhaled iloprost therapy in patients with idiopathic pulmonary arterial hypertension
-
Opitz C, Wensel R, Winkler J, et al. Clinical efficacy and survival with first-line inhaled iloprost therapy in patients with idiopathic pulmonary arterial hypertension. Eur Heart J. 2005;26:1895-1902.
-
(2005)
Eur Heart J
, vol.26
, pp. 1895-1902
-
-
Opitz, C.1
Wensel, R.2
Winkler, J.3
-
70
-
-
0036569119
-
Effects of beraprost sodium, an oral prostacyclin analogue, in patients with pulmonary arterial hypertension: A randomized, double-blind, placebo controlled trial
-
Galie N, Humbert M, Vachiery J, et al. Effects of beraprost sodium, an oral prostacyclin analogue, in patients with pulmonary arterial hypertension: A randomized, double-blind, placebo controlled trial. J Am Coll Cardiol. 2002;39:1496-1502.
-
(2002)
J Am Coll Cardiol
, vol.39
, pp. 1496-1502
-
-
Galie, N.1
Humbert, M.2
Vachiery, J.3
-
71
-
-
0038037766
-
Beraprost therapy for pulmonary arterial hypertension
-
Barst R, McGoon M, McLaughlin V, et al. Beraprost therapy for pulmonary arterial hypertension. J Am Coll Cardiol. 2003;41: 2119-2125.
-
(2003)
J Am Coll Cardiol
, vol.41
, pp. 2119-2125
-
-
Barst, R.1
McGoon, M.2
McLaughlin, V.3
-
72
-
-
3042686863
-
Effect of orally active pros-tacyclin analogue on survival of outpatients with primary pulmonary hypertension
-
Nagaya N, Uematsu M, Okano Y, et al. Effect of orally active pros-tacyclin analogue on survival of outpatients with primary pulmonary hypertension. J Am Coll Cardiol. 1999;34:1188-1192.
-
(1999)
J Am Coll Cardiol
, vol.34
, pp. 1188-1192
-
-
Nagaya, N.1
Uematsu, M.2
Okano, Y.3
-
73
-
-
28044465945
-
Potent effects of aerosol compared with intravenous treprostinil on the pulmonary circulation
-
Sandifer B, Brigham K, Lawrence E, Mottola D, Cuppels C, Parker R. Potent effects of aerosol compared with intravenous treprostinil on the pulmonary circulation. J Appl Physiol. 2005;99:2363-2368.
-
(2005)
J Appl Physiol
, vol.99
, pp. 2363-2368
-
-
Sandifer, B.1
Brigham, K.2
Lawrence, E.3
Mottola, D.4
Cuppels, C.5
Parker, R.6
-
74
-
-
33644797883
-
Inhaled trepro-stinil for treatment of chronic pulmonary arterial hypertension
-
Voswinckel R, Ghofrani H, Grimminger F, Seeger W. Inhaled trepro-stinil for treatment of chronic pulmonary arterial hypertension. Ann Intern Med. 2006;144:149-150.
-
(2006)
Ann Intern Med
, vol.144
, pp. 149-150
-
-
Voswinckel, R.1
Ghofrani, H.2
Grimminger, F.3
Seeger, W.4
-
75
-
-
33749537060
-
Favorable effects of inhaled treprostinil in severe pulmonary hypertension: Results from randomized controlled pilot studies
-
Voswinckel R, Enke B, Reichenberger R, et al. Favorable effects of inhaled treprostinil in severe pulmonary hypertension: Results from randomized controlled pilot studies. J Am Coll Cardiol. 2006;48: 1672-1681.
-
(2006)
J Am Coll Cardiol
, vol.48
, pp. 1672-1681
-
-
Voswinckel, R.1
Enke, B.2
Reichenberger, R.3
-
76
-
-
33748931278
-
Safety and efficacy of inhaled treprostinil as add-on therapy to bosentan in pulmonary arterial hypertension
-
Channick R, Olschewski H, Seeger W, Staub T, Voswinckel R, Rubin L. Safety and efficacy of inhaled treprostinil as add-on therapy to bosentan in pulmonary arterial hypertension. J Am Coll Cardiol. 2006;48:1433-1437.
-
(2006)
J Am Coll Cardiol
, vol.48
, pp. 1433-1437
-
-
Channick, R.1
Olschewski, H.2
Seeger, W.3
Staub, T.4
Voswinckel, R.5
Rubin, L.6
-
77
-
-
50849116416
-
Acute effects of the combination of sildenafil and inhaled treprostinil on haemodynamics and gas exchange in pulmonary hypertension
-
Voswinckel H, Reichenberger F, Enke B, et al. Acute effects of the combination of sildenafil and inhaled treprostinil on haemodynamics and gas exchange in pulmonary hypertension. Pulm Pharmacol Ther. 2008;21:824-832.
-
(2008)
Pulm Pharmacol Ther
, vol.21
, pp. 824-832
-
-
Voswinckel, H.1
Reichenberger, F.2
Enke, B.3
-
78
-
-
58349110755
-
Metered dose inhaler delivery of treprostinil for the treatment of pulmonary hypertension
-
Voswinckel R, Reichenberger F, Gall H, et al. Metered dose inhaler delivery of treprostinil for the treatment of pulmonary hypertension. Pulm Pharmacol Ther. 2009;22:50-56.
-
(2009)
Pulm Pharmacol Ther
, vol.22
, pp. 50-56
-
-
Voswinckel, R.1
Reichenberger, F.2
Gall, H.3
-
79
-
-
80051905431
-
-
Research Triangle Park, NC: United Therapeutics Corp
-
Tyvaso Prescribing Information. Research Triangle Park, NC: United Therapeutics Corp; 2010.
-
(2010)
Tyvaso Prescribing Information
-
-
|