Suppression of retinoid X receptor alpha and aberrant β-catenin expression significantly associates with progression of colorectal carcinoma

European Journal of Cancer

Volumn 47, Issue 13, 2011, Pages 2060-2067

  Zhang, Fenfen ^a   Meng, Fengjiao ^a   Li, Hui ^a   Dong, Yu ^a   Yang, Wancai ^b   Han, Anjia ^a  

^a SUN YAT SEN UNIVERSITY   (China)

^b UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

Catenin; Clinicopathology; Colorectal carcinoma; Retinoid X receptor alpha

Indexed keywords

BETA CATENIN; MESSENGER RNA; RETINOID X RECEPTOR ALPHA;

ADULT; ARTICLE; CANCER CLASSIFICATION; CANCER GROWTH; CANCER STAGING; CLINICAL FEATURE; COLORECTAL CARCINOMA; CONTROLLED STUDY; DOWN REGULATION; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LYMPH NODE METASTASIS; MALE; METHYLATION; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; UPREGULATION; WESTERN BLOTTING;

BETA CATENIN; BLOTTING, WESTERN; COLORECTAL NEOPLASMS; DISEASE PROGRESSION; DNA METHYLATION; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; LYMPHATIC METASTASIS; MALE; MIDDLE AGED; REAL-TIME POLYMERASE CHAIN REACTION; RETINOID X RECEPTOR ALPHA; RNA, MESSENGER;

EID: 80051871007     PISSN: 09598049     EISSN: 18790852     Source Type: Journal    
DOI: 10.1016/j.ejca.2011.04.010     Document Type: Article

References (33)

1. D.W. Kang, K.Y. Choi, and D.S. Min Phospholipase D meets Wnt signaling: a new target for cancer therapy Cancer Res 71 2 2011 293 297
2. D.W. Kang, and D.S. Min Positive feedback regulation between phospholipase D and Wnt signaling promotes Wnt-driven anchorage-independent growth of colorectal cancer cells PLoS One 5 8 2010 e12109
3. N.A. Wong, and M. Pignatelli β-Catenin - a linchpin in colorectal carcinogenesis? Am J Pathol 160 2 2002 389 401
4. N. Chikazawa, H. Tanaka, and T. Tasaka Inhibition of Wnt signaling pathway decreases chemotherapy-resistant side-population colon cancer cells Anticancer Res 30 6 2010 2041 2048
5. C.J. Grubbs, R.A. Lubet, and V.R. Atigadda Efficacy of new retinoids in the prevention of mammary cancers and correlations with short-term biomarkers Carcinogenesis 27 6 2006 1232 1239 (Pubitemid 43985438)
6. L.A. Hansen, C.C. Sigman, and F. Andreola Retinoids in chemoprevention and differentiation therapy Carcinogenesis 21 7 2000 1271 1279 (Pubitemid 30455984)
7. P. Chambon A decade of molecular biology of retinoic acid receptors FASEB J 10 9 1996 940 954 (Pubitemid 26285969)
8. D.J. Mangelsdorf, and R.M. Evans The RXR heterodimers and orphan receptors Cell 83 6 1995 841 850 (Pubitemid 26006526)
9. D.J. Mangelsdorf, C. Thummel, and M. Beato The nuclear receptor superfamily: the second decade Cell 83 6 1995 835 839
10. Y. Wang, R. Yao, and A. Maciag Organ-specific expression profiles of rat mammary gland, liver, and lung tissues treated with targretin, 9-cis retinoic acid, and 4-hydroxyphenylretinamide Mol Cancer Ther 5 4 2006 1060 1072 (Pubitemid 43724607)
11. R.A. Heyman, D.J. Mangelsdorf, and J.A. Dyck 9-Cis retinoic acid is a high affinity ligand for the retinoid X receptor Cell 68 2 1992 397 406
12. A.A. Levin, L.J. Sturzenbecker, and S. Kazmer 9-Cis retinoic acid stereoisomer binds and activates the nuclear receptor RXR alpha Nature 355 6358 1992 359 361
13. D.J. Mulholland, S. Dedhar, G.A. Coetzee, and C.C. Nelson Interaction of nuclear receptors with the Wnt/beta-catenin/Tcf signaling axis: Wnt you like to know? Endocr Rev 26 7 2005 898 915 (Pubitemid 41770157)
14. S. Shah, A. Hecht, R. Pestell, and S.W. Byers Trans-repression of beta-catenin activity by nuclear receptors J Biol Chem 278 48 2003 48137 48145 (Pubitemid 37523266)
15. S. Byers, M. Pishvaian, and C. Crockett Retinoids increase cell-cell adhesion strength, beta-catenin protein stability, and localization to the cell membrane in a breast cancer cell line: a role for serine kinase activity Endocrinology 137 8 1996 3265 3273 (Pubitemid 26250173)
16. A. Han, C. Tong, D. Hu, X. Bi, and W. Yang A direct protein-protein interaction is involved in the suppression of beta-catenin transcription by retinoid X receptor alpha in colorectal cancer cells Cancer Biol Ther 7 3 2008 454 459 (Pubitemid 351847067)
17. 2-terminal kinase 1 plays a critical role in intestinal homeostasis and tumor suppression Am J Pathol 171 1 2007 297 303 (Pubitemid 47339246)
18. K. Maruyama, A. Ochiai, and S. Akimoto Cytoplasmic beta-catenin accumulation as a predictor of hematogenous metastasis in human colorectal cancer Oncology 59 4 2000 302 309
19. S.M. Lee, J.Y. Lee, and J.E. Choi Epigenetic inactivation of retinoid X receptor genes in non-small cell lung cancer and the relationship with clinicopathologic features Cancer Genet Cytogenet 197 1 2010 39 45
20. N.C. Ha, T. Tonozuka, J.L. Stamos, H.J. Choi, and W.I. Weis Mechanism of phosphorylation-dependent binding of APC to beta-catenin and its role in beta-catenin degradation Mol Cell 15 4 2004 511 521 (Pubitemid 39141779)
21. S. Amit, A. Hatzubai, and Y. Birman Axin-mediated CKI phosphorylation of beta-catenin at Ser 45: a molecular switch for the Wnt pathway Genes Dev 16 9 2002 1066 1076 (Pubitemid 34507196)
22. J. Liu, J. Stevens, and C.A. Rote Siah-1 mediates a novel beta-catenin degradation pathway linking p53 to the adenomatous polyposis coli protein Mol Cell 7 5 2001 927 936 (Pubitemid 32525740)
23. S.I. Matsuzawa, and J.C. Reed Siah-1, SIP, and Ebi collaborate in a novel pathway for beta-catenin degradation linked to p53 responses Mol Cell 7 5 2001 915 926 (Pubitemid 32525739)
24. A.C. Dillard, and M.A. Lane Retinol decreases beta-catenin protein levels in retinoic acid-resistant colon cancer cell lines Mol Carcinog 46 4 2007 315 329 (Pubitemid 46613734)
25. J.H. Xiao, C. Ghosn, and C. Hinchman Adenomatous polyposis coli (APC)-independent regulation of beta-catenin degradation via a retinoid X receptor-mediated pathway J Biol Chem 278 32 2003 29954 29962 (Pubitemid 36962384)
26. V. Easwaran, and M. Pishvaian Salimuddin, Byers S. Cross-regulation of beta-catenin-LEF/TCF and retinoid signaling pathways Curr Biol 9 23 1999 1415 1418
27. M.J. Larriba, N. Valle, and H.G. Palmer The inhibition of Wnt/beta-catenin signalling by 1alpha, 25-dihydroxyvitamin D3 is abrogated by Snail1 in human colon cancer cells Endocr Relat Cancer 14 1 2007 141 151 (Pubitemid 47521730)
28. S. Shah, M.N. Islam, and S. Dakshanamurthy The molecular basis of vitamin D receptor and beta-catenin crossregulation Mol Cell 21 6 2006 799 809 (Pubitemid 43376130)
29. H.G. Palmer, J.M. Gonzalez-Sancho, and J. Espada Vitamin D(3) promotes the differentiation of colon carcinoma cells by the induction of E-cadherin and the inhibition of beta-catenin signaling J Cell Biol 154 2 2001 369 387 (Pubitemid 34286147)
30. A.C. Dillard, and M.A. Lane Retinol Increases beta-catenin-RXRalpha binding leading to the increased proteasomal degradation of beta-catenin and RXRalpha Nutr Cancer 60 1 2008 97 108 (Pubitemid 351186220)
31. S.M. Lee, J.Y. Lee, and J.E. Choi Epigenetic inactivation of retinoid X receptor genes in non-small cell lung cancer and the relationship with clinicopathologic features Cancer Genet Cytogenet 197 1 2010 39 45
32. E.M. Youssef, M.R. Estecio, and J.P. Issa Methylation and regulation of expression of different retinoic acid receptor beta isoforms in human colon cancer Cancer Biol Ther 3 1 2004 82 86 (Pubitemid 41342425)
33. S.R. Volate, S.J. Muga, and A.Y. Issa Epigenetic modulation of the retinoid X receptor alpha by green tea in the azoxymethane-Apc Min/+ mouse model of intestinal cancer Mol Carcinog 48 10 2009 920 933