Retinoids increase cell-cell adhesion strength, β-catenin protein stability, and localization to the cell membrane in a breast cancer cell line: A role for serine kinase activity

Endocrinology

Volumn 137, Issue 8, 1996, Pages 3265-3273

  Byers, Stephen ^a,c   Pishvaian, Michael ^a   Crockett, Caroline ^a   Peer, Christopher ^c   Tozeren, Aydin ^b   Sporn, Michael ^c   Anzano, Mario ^c   Lechleider, Robert ^c  

^a GEORGETOWN UNIVERSITY   (United States)

^b Catholic University of America ^*  (United States)

^c NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1ALPHA,25 DIHYDROXY 16 ENE 23 YNE 26,27 HEXAFLUOROCHOLECALCIFEROL; 26,26,26,27,27,27!HEXAFLUORO 9,10 SECOCHOLESTA 5,7,10(19),16 TETRAENE 23 YNE 1,3,25 TRIOL; 4 (5,6,7,8 TETRAHYDRO 5,5,8,8 TETRAMETHYL 2 ANTHRYL)BENZOIC ACID; ALITRETINOIN; BETA CATENIN; BISINDOLYLMALEIMIDE; CALCIUM; CALPASTATIN; COLECALCIFEROL DERIVATIVE; CYCLOHEXIMIDE; DACTINOMYCIN; GENISTEIN; HEPARIN; HERBIMYCIN; LIGAND; MATRIGEL; OKADAIC ACID; PROTEIN KINASE INHIBITOR; PROTEIN SERINE KINASE; RETINOIC ACID; RETINOIC ACID RECEPTOR; RETINOID; RETINOID X RECEPTOR; RO 24 5531; SRI 1217; STAUROSPORINE; SURAMIN; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG;

ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CELL ADHESION; CONTROLLED STUDY; ENZYME ACTIVITY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN STABILITY; RNA SYNTHESIS;

EID: 0029891786     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.137.8.8754749     Document Type: Article

References (45)

1. Takeichi M 1990 Cadherins: a molecular family important in selective cell-cell adhesion. Annu Rev Biochem 59:237-252
2. Takeichi M 1991 Cadherin cell adhesion receptors as a morphogenetic regulator. Science 251:1451-1455
3. Kemler R 1993 From cadherins to catenins-cytoplasmic protein interactions and regulation of cell adhesion. Trends Genet 9:317-321
4. Sommers CL, Gelmann EP, Kemler R, Cowin P, Byers SW 1994 Alterations in plakoglobin expression and beta-catenin phosphorylation in human breast cancer cell lines. Cancer Res 54:3544-3552
5. Matsuyoshi N, Hamaguchi M, Taniguchi S, Nagafuchi A, Tsukita S, Takeichi M 1992 Cadherin-mediated cell-cell adhesion is perturbed by v-src tyrosine phosphorylation in metastatic fibroblasts. J Cell Biol 118:703-714
6. Sommers CL, Thompson EW, Torri JA, Kemler R, Gelmann EP, Byers SW 1991 Cell adhesion molecule uvomorulin expression in human breast cancer cell lines: relationship to morphology and invasive capacities. Cell Growth Differ 2:365-372
7. Sommers C, Heckford SE, Skerker JM, Worland P, Thompson EW, Byers SW, Gelman EP 1992 Loss of epithelial markers and acquisition of vimentin expression in adriamycin- and vinbastine-resistant breast cancer cell lines. Cancer Res 52:5190-5197
8. Sommers CL, Byers SW, Thompson EW, Torri JA, Gelmann EP 1994 Differentiation state and invasiveness of human breast cancer cell lines. Breast Cancer Res Treat 31:325-335
9. Frixen UH, Behrens J, Sachs M, Eberle G, Voss B, Warda A, Lochner D, Birchmeier W 1991 E-Cadherin-mediated cell-cell adhesion prevents invasiveness of human carcinoma cells. J Cell Biol 113:173-185
10. Hirano S, Kimoto N, Shimoyama Y, Hirohashi S, Takeichi M 1992 Identification of a neural alpha-catenin as a key regulator of cadherin function and multicellular organization. Cell 70:293-301
11. Navarro P, Lozano E, Cano A 1993 Expression of E- or P-cadherin is not sufficient to modify the morphology and the tumorigenic behavior of murine spindle carcinoma cells. Possible involvement of plakoglobin. J Cell Sci 105:923-934
12. Fearon ER, Vogelstein B 1990 A genetic model for colorectal tumorigenesis. Cell 61:759-767
13. Cho KR, Vogelstein B 1992 Genetic alterations in the adenoma-carcinoma sequence. Cancer 70:1727-1731
14. Gudas LJ, Sporn MB, Roberts AB, Sporn MB, Roberts AB, Goodman DS, eds 1994 The Retinoids: Biology, Chemistry, and Medicine, ed 2. Raven Press, New York, pp 443-520
15. Mangelsdorf DJ, Kliewer SA, Kakizuka A, Umesono K, Evans RM 1993 Retinoid receptors. Recent Prog Horm Res 48:99-121
16. McCrea PD, Brieher WM, Gumbiner BM 1993 Induction of a secondary body axis in Xenopus by antibodies to beta-catenin. J Cell Biol 123:477-484
17. Lotan R, Dawson MI, Zou CC, Jong L, Lotan D, Zou CP 1995 Enhanced efficacy of combinations of retinoic acid- and retinoid × receptor-selective retinoids and alpha-interferon in inhibition of cervical carcinoma cell proliferation. Cancer Res 55:232-236
18. Lehmann JM, Jong L, Fanjul A, Cameron JF, Lu XP, Haefner P, Dawson MI, Pfahl M 1992 Retinoids selective for retinoid × receptor response pathways. Science 258:1944-1946
19. Byers SW, Sommers CL, Hoxter E, Mercurio AM, Tozeren A 1995 The role of E-cadherin in the response of tumor cell aggregates to lymphatic, venous and arterial flow: measurement of cell-cell adhesion strength. J Cell Sci 108:2053-2064
20. Lechleider RJ, Freeman RMJ, Neel BG 1993 Tyrosyl phosphorylation and growth factor receptor association of the human corkscrew homologue, SHPTP2. J Biol Chem 268:13434-13438
21. Bacus SS, Huberman E, Chin D, Kiguchi K, Simpson S, Lippman M, Lupu R 1992 A ligand for the erbB-2 oncogene product (gp30) induces differentiation of human breast cancer cells. Cell Growth Differ 3:401-411
22. Lupu R, Dickson RB, Lippman ME 1992 The role of erbB-2 and its ligands in growth control of malignant breast epithelium. J Steroid Biochem Mol Biol 43:229-236
23. Lupu R, Colomer R, Kannan B, Lippman ME 1992 Characterization of a growth factor that binds exclusively to the erbB-2 receptor and induces cellular responses. Proc Natl Acad Sci USA 89:2287-2291
24. Stabler A, Sommers CL, Mueller S, Byers S, Thompson EW, Lupu R 1994 Modulation of breast cancer progression and differentiation by the erbB-2 ligand. Breast Cancer Res Treat 31:175-182
25. Toullec D, Pianetti P, Coste H, Bellevergue P, Grand Perret T, Ajakane M, Baudet V, Boissin P, Boursier E, Loriolle F, Dahamel L, Charon D, Kirilousky J 1991 The bisindolylmaleimide GF 109203X is a potent and selective inhibitor of protein kinase C. J Biol Chem 266:15771-15781
26. Glick AB, McCune BK, Abdulkarem N, Flanders KC, Lumadue JA, Smith JM, Sporn MB 1991 Complex regulation of TGF beta expression by retinoic acid in the vitamin A-deficient rat. Development 111:1081-1086
27. Wakefield L, Kim SJ, Glick A, Winokur T, Colletta A, Sporn M 1990 Regulation of transforming growth factor-beta subtypes by members of the steroid hormone superfamily. J Cell Sci [Suppl] 13:139-148
28. Sporn MB, Roberts AB 1991 Interactions of retinoids and transforming growth factor-beta in regulation of cell differentiation and proliferation. Mol Endocrinol 5:3-7
29. Jue SF, Bradley RS, Rudnicki JA, Varmus HE, Brown AM 1992 The mouse Wnt-1 gene can act via a paracrine mechanism in transformation of mammary epithelial cells. Mol Cell Biol 12:321-328
30. Anzano MA, Byers SW, Smith JM, Peer CW, Mullen LT, Brown CC, Roberts AB, Sporn MB 1994 Prevention of breast cancer in the rat with 9-cis retinoic acid as a single agent and in combination with tamoxifen. Cancer Res 54:4614-4617
31. Pierceall WE, Woodard AS, Morrow JS, Rimm D, Fearon ER 1995 Frequent alterations in E-cadherin and alpha and beta catenin expression in human breast cancer cell lines. Oncogene 11:1319-1326
32. D'Souza B, Taylor Papadimitriou J 1994 Overexpression of erbB-2 in human mammary epithelial cells signals inhibition of transcription of the E-cadherin gene. Proc Natl Acad Sci 91:7202-7206
33. van Leeuwen F, Samos CH, Nusse R 1994 Biological activity of soluble wingless protein in cultured Drosophila imaginal disc cells. Nature 368:342-344
34. Su L, Vogelstein B, Kinzler KW 1993 Association of the APC tumor suppressor protein with catenins. Science 262:1734-1737
35. Rubinfeld B, Souza B, Albert I, Munemitsu S, Polakis P 1995 The APC protein and E-cadherin form similar but independent complexes with alpha-catenin, beta-catenin, and plakoglobin. J Biol Chem 270:5549-5555
36. Hulsken J, Birchmeier W, Behrens J 1994 E-Cadherin and APC compete for the interaction with beta-catenin and the cytoskeleton. J Cell Biol 127:2061-2069
37. Vermeulen S, Bruyneel E, VanRoy F, Mareel M, Bracke M 1995 Activation of the E-cadherin/catenin complex in human MCF-7 breast cancer cells by all trans-retinoic acid. Br J Cancer 72:1447-1453
38. Helms J, Thaller C, Eichele G 1994 Relationship between retinoic acid and sonic hedgehog, two polarizing signals in the chick wing bud. Development 120:3267-3274
39. Gelbart WM 1989 The decapentaplegic gene: a TGF-beta homologue controlling pattern formation in Drosophila. Development [Suppl] 107:65-74
40. Bradley RS, Cowin P, Brown AMC 1993 Expression of wnt-1 in PC-12 cells results in modulation of plakoglobin and E-cadherin and increased cellular adhesion. J Cell Biol 123:1857-1865
41. Hinck L, Nelson WJ, Papkoff J 1994 wnt-1 modulates cell-cell adhesion in mammalian cells by stabilizing beta-catenin binding to the cell adhesion protein cadherin. J Cell Biol 124:729-741
42. Huguet EL, McMahon JA, McMahon AP, Bicknell R, Harris AL 1994 Differential expression of human wnt genes 2, 3, 4, and 7B in human breast cell lines and normal and disease states of human breast tissue. Cancer Res 54:2615-2621
43. Munemitsu S, Albert I, Souza B, Rubinfeld B, Polakis P 1995 Regulation of intracellular beta-catenin levels by the adenomatous polyposis coli (APC) tumor-suppressor protein. Proc Natl Acad Sci USA 92:3046-3050
44. Winkel GK, Ferguson JE, Takeichi M, Nuccitelli R 1990 Activation of protein kinase C triggers premature compaction in the four-cell stage mouse embryo. Dev Biol 138:1-15
45. Stappert J, Kemler R 1994 A short core region of E-cadherin is essential for catenin binding and is highly phosphorylated. Cell Ad Commun 2:319-327