Nitric oxide activity through guanylate cyclase and phosphodiesterase modulation is impaired in fetal lambs with congenital diaphragmatic hernia

Journal of Pediatric Surgery

Volumn 46, Issue 8, 2011, Pages 1516-1522

  De Buys Roessingh, Anthony ^a,b   Fouquet, Virginie ^a,b   Aigrain, Yves ^a   Mercier, Jean Christophe ^b   De Lagausie, Pascal ^a,b   Dinh Xuan, Anh Tuan ^b  

^a HÔPITAL ROBERT DEBRÉ   (France)

^b ASSISTANCE PUBLIQUE HÔPITAUX DE PARIS   (France)

Author keywords

Guanylate cyclase; NO; Phosphodiesterase; Pulmonary hypertension; Pulmonary vascular resistance

Indexed keywords

GUANYLATE CYCLASE; METHYL 2 (4 AMINOPHENYL) 1,2 DIHYDRO 1 OXO 7 (2 PYRIDINYLMETHOXY) 4 (3,4,5 TRIMETHOXYPHENYL) 3 ISOQUINOLINE CARBOXYLATE SULFATE; NITRIC OXIDE; NITROPRUSSIDE SODIUM; PHOSPHODIESTERASE; PHOSPHODIESTERASE V; PHOSPHODIESTERASE V INHIBITOR; UNCLASSIFIED DRUG; ZAPRINAST;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD FLOW; CATHETER; CONGENITAL DIAPHRAGM HERNIA; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; FETUS; GESTATIONAL AGE; IN VITRO STUDY; IN VIVO STUDY; LUNG BLOOD VESSEL; LUNG HEMODYNAMICS; LUNG VASCULAR RESISTANCE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; VASCULAR RING; VASODILATATION;

ANIMALS; CYCLIC NUCLEOTIDE PHOSPHODIESTERASES, TYPE 5; FETUS; GUANYLATE CYCLASE; HERNIA, DIAPHRAGMATIC; HYPERTENSION, PULMONARY; NITRIC OXIDE; NITROPRUSSIDE; PHOSPHODIESTERASE 5 INHIBITORS; PULMONARY ARTERY; SHEEP; SIGNAL TRANSDUCTION; VASCULAR RESISTANCE;

EID: 80051866190     PISSN: 00223468     EISSN: 15315037     Source Type: Journal    
DOI: 10.1016/j.jpedsurg.2010.12.015     Document Type: Article

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