Inhaled Nitric Oxide in the Premature Newborn

Journal of Pediatrics

Volumn 151, Issue 1, 2007, Pages 10-15

  Kinsella, John P ^a   Abman, Steven H ^b  

^a Pediatric Heart Lung Center   (United States)

^b UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NITRIC OXIDE;

ANGIOGENESIS; ARTICLE; ASSISTED VENTILATION; CLINICAL STUDY; HUMAN; LUNG ARTERY PRESSURE; LUNG CIRCULATION; LUNG DYSPLASIA; OXIDATIVE STRESS; PERFUSION; PNEUMONIA; PREMATURITY; PRIORITY JOURNAL; PULMONARY HYPERTENSION; RESPIRATORY FAILURE;

ADMINISTRATION, INHALATION; BRONCHOPULMONARY DYSPLASIA; FEMALE; FOLLOW-UP STUDIES; HUMANS; INFANT, NEWBORN; INFANT, PREMATURE; MALE; NITRIC OXIDE; PULMONARY GAS EXCHANGE; RANDOMIZED CONTROLLED TRIALS; RESPIRATORY DISTRESS SYNDROME, NEWBORN; RESPIRATORY FUNCTION TESTS; RISK ASSESSMENT; TREATMENT OUTCOME;

EID: 34250631360     PISSN: 00223476     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpeds.2007.02.010     Document Type: Article

References (53)

1. Kinsella J.P., Neish S.R., Shaffer E., and Abman S.H. Low-dose inhalational nitric oxide in persistent pulmonary hypertension of the newborn. Lancet 340 (1992) 819-820
2. Roberts J.D., Polaner D.M., Lang P., and Zapol W.M. Inhaled nitric oxide in persistent pulmonary hypertension of the newborn. Lancet 340 (1992) 818-819
3. Clark R.H., Kueser T.J., Walker M.W., Southgate W.M., Huckaby J.L., Perez J.A., et al. Randomized, controlled trial of low-dose inhaled nitric oxide treatment of persistent pulmonary hypertension of the newborn. N Engl J Med 17 (2000) 342 469-74
4. Neonatal Inhaled Nitric Oxide Study Group. Inhaled nitric oxide in full-term and nearly full-term infants with hypoxic respiratory failure. N Engl J Med 336 (1997) 597-604
5. Northway W.H., Rosan R.C., and Porter D.Y. Pulmonary disease following respirator therapy of hyaline-membrane disease. Bronchopulmonary dysplasia. N Engl J Med 276 (1967) 357-368
6. Abman S.H., Kinsella J.P., Schaffer M.S., and Wilkening R.B. Inhaled nitric oxide in the management of a premature newborn with severe respiratory distress and pulmonary hypertension. Pediatrics 92 (1993) 606-609
7. Kinsella J.P., McQueston J., Rosenberg A.A., and Abman S.H. Hemodynamic effects of exogenous nitric oxide in ovine transitional pulmonary circulation. Am J Physiol 262 (1992) H875-H880
8. Roberts J.D., Chen T.Y., Kawai N., Wain J., Dupuy P., Shimouchi A., et al. Inhaled nitric oxide reverses pulmonary vasoconstriction in the hypoxic and acidotic newborn lamb. Circ Res 72 (1993) 246-254
9. Kinsella J.P., Ivy D.D., and Abman S.H. Ontogeny of NO activity and response to inhaled NO in the developing ovine pulmonary circulation. Am J Physiol 267 (1994) H1955-H1961
10. Kinsella J.P., Ivy D.D., and Abman S.H. Inhaled nitric oxide lowers pulmonary vascular resistance and improves gas exchange in severe experimental hyaline membrane disease. Pediatr Res 36 (1994) 402-408
11. Kanwar S., and Kubes P. Nitric oxide is an antiadhesive molecule for leukocytes. New Horizons 3 (1995) 93-104
12. Kinsella J.P., Parker T.A., Galan H., Sheridan B.C., Halbower A.C., and Abman S.H. Effects of inhaled nitric oxide on pulmonary edema and lung neutrophil accumulation in severe experimental hyaline membrane disease. Pediatr Res 41 (1997) 457-463
13. Merritt T.A., Cochrane C.G., Holcomb K., Bohl B., Hallman M., Strayer D., et al. Elastase and α-1-proteinase inhibitor activity in tracheal aspirates during respiratory distress syndrome. J Clin Invest 72 (1983) 656-666
14. Ogden B.E., Murphy S., Saunders G.C., and Johnson J.D. Lung lavage of newborns with respiratory distress syndrome: prolonged neutrophil influx is associated with bronchopulmonary dysplasia. Chest 83 (1983) 31-33
15. Speer C.P., Ruess D., Harms K., Herting E., and Gefeller O. Neutrophil elastase and acute pulmonary damage in neonates with severe respiratory distress syndrome. Pediatrics 91 (1993) 794-799
16. Brus F., Van Oeveren W., Heikamp A., Okken A., and Oetomo S.B. Leakage of protein into lungs of preterm ventilated rabbits is correlated with activation of clotting, complement, and polymorphonuclear leukocytes in plasma. Pediatr Res 39 (1996) 958-965
17. Storme L., Zerimech F., Riou Y., Martin-Ponthieu A., Devisme L., Slomianny C., et al. Inhaled nitric oxide neither alters oxidative stress parameters nor induces lung inflammation in premature lambs with moderate hyaline membrane disease. Bio Neo 73 (1998) 172-181
18. Nelin L.D., Welty S.E., Morrisey J.F., and Dawson C.A. Nitric oxide increases the survival of rats with a high oxygen exposure. Pediatr Res 43 (1998) 727-732
19. Gutierrez H.H., Nieves B., Chumley P., Rivera A., and Freeman B.A. Nitric oxide regulation of superoxide-dependent lung injury: oxidant-protective actions of endogenously produced and exogenously administered nitric oxide. Free Radic Biol Med 21 (1996) 43-52
20. Issa A., Lappalainen U., Kleinman M., Bry K., and Hallman M. Inhaled nitric oxide decreases hyperoxia-induced surfactant abnormality in preterm rabbits. Pediatr Res 45 (1999) 247-254
21. MacRitchie A.N., Albertine K.H., Sun J., Lei P.S., Jensen S.C., Freestone A.A., et al. Reduced endothelial nitric oxide synthase in lungs of chronically ventilated preterm lambs. Am J Physiol Lung Cell Mol Physiol 281 (2001) L1011-L1020
22. Afshar S., Gibson L.L., Yuhanna I.S., Sherman T.S., Kerecman J.D., Grubb P.H., et al. Pulmonary NO synthase expression is attenuated in a fetal baboon model of chronic lung disease. Am J Physiol Lung Cell Mol Physiol 284 (2003) L749-L758
23. Han R.N., Babaei S., Robb M., Lee T.L., Risdale R., Ackerley C., et al. Defective lung vascular development and fatal respiratory distress in eNOS deficient mice: a model of alveolar capillary dysplasia?. Circ Res 94 (2004) 1115-1123
24. Balasubramaniam V., Tang J.R., Maxey A., Plopper C.G., and Abman S.H. Mild hypoxia impairs alveolarization in the endothelial nitric oxide synthase-deficient mouse. Am J Physiol Lung Cell Mol Physiol 284 (2003) L964-L971
25. Tang J.R., Markham N.E., Lin Y.J., McMurty I.F., Maxey A., Kinsella J.P., et al. Inhaled nitric oxide attenuates pulmonary hypertension and improves lung growth in infant rats after neonatal treatment with a VEGF receptor inhibitor. Am J Physiol Lung Cell Mol Physiol 287 (2004) L344-L351
26. Lin Y.J., Markham N.E., Balasubramaniam V., Tang J.R., Maxey A., Kinsella J.P., et al. Inhaled nitric oxide enhances distal lung growth after exposure to hyperoxia in neonatal rats. Pediatr Res 58 (2005) 22-29
27. McCurnin D.C., Pierce R.A., Chang L.Y., Gibson L.L., Osborne-Lawrence S., Yoder B.A., et al. Inhaled NO improves early pulmonary function and modifies lung growth and elastin deposition in a baboon model of neonatal chronic lung disease. Am J Physiol - Lung 288 (2005) 450-459
28. Bland R.D., Albertine K.H., Carlton D.P., and MacRitchie A.J. Inhaled nitric oxide effects on lung structure and function in chronically ventilated preterm lambs. Am J Respir Crit Care Med 172 (2005) 899-906
29. Peliowski A., Finer N.N., Etches P.C., Tierney A.J., and Ryan C.A. Inhaled nitric oxide for premature infants after prolonged rupture of the membranes. J Pediatr 126 (1995) 450-453
30. Meurs K.P., Rhine W.D., Asselin J.M., Duran D.J., and Preemie NO Collaborative Group. Response of premature infants with severe respiratory failure to inhaled nitric oxide. Pediatr Pulmonol 24 (1997) 319-323
31. Abman S.H. Bronchopulmonary dysplasia: a "vascular hypothesis.". Am J Respir Crit Care Med 164 (2001) 1755-1756
32. Hogman M., Frostell C., Arnberg H., and Hedenstierna G. Bleeding time prolongation and NO inhalation. Lancet 341 (1993) 1664-1665
33. Simon D.I., Stamler J.S., Jaraki O., Keaney J.F., Osborne J.A., Francis S.A., et al. Antiplatelet properties of protein S-nitrosothiols derived from nitric oxide and endothelium-derived relaxing factor. Arterioscler Thromb 13 (1993) 791-799
34. George T.N., Johnson K.J., Bates J.N., and Segar J.L. The effect of inhaled nitric oxide therapy on bleeding time and platelet aggregation in neonates. J Pediatr 132 (1998) 731-734
35. Subhedar N.V., Ryan S.W., and Shaw N.J. Open randomised controlled trial of inhaled nitric oxide and early dexamethasone in high risk preterm infants. Arch Dis Child 77 (1997) F185-F190
36. Kinsella J.P., Walsh W.F., Bose C.L., Gerstmann D.R., Labella J.J., Sardesai S., et al. Inhaled nitric oxide in premature neonates with severe hypoxaemic respiratory failure: a randomised controlled trial. Lancet 354 (1999) 1061-1065
37. The Franco-Belgium Collaborative NO Trial Group. Early compared with delayed inhaled nitric oxide in moderately hypoxaemic neonates with respiratory failure: a randomised controlled trial. Lancet 354 (1999) 1066-1071
38. Hascoet J.M., Fresson J., Claris O., Hamon I., Lombet J., Liska A., et al. The safety and efficacy of nitric oxide therapy in premature infants. J Pediatr 146 (2005) 318-323
39. Finer N.N. Inhaled nitric oxide for preterm infants: a therapy in search of an indication?. The search continues. J Pediatr 146 (2005) 301-302
40. Hamon I., Fresson J., Nicolas M.B., Buchweiller M.C., Franck P., and Hascoet J.M. Early inhaled nitric oxide improves oxidative balance in very preterm infants. Pediatr Res 57 (2005) 637-643
41. Field D., Elbourne D., Truesdale A., Grieve R., Hardy P., Fenton A.C., et al. Neonatal ventilation with inhaled nitric oxide versus ventilatory support without inhaled nitric oxide for preterm infants with severe respiratory failure: the INNOVO multicentre randomized controlled trial. Pediatrics 115 (2005) 926-936
42. Field D.J. Nitric oxide-still no consensus. Early Human Development 81 (2005) 1-4
43. Schreiber M.D., Gin-Mestan K., Marks J.D., Huo D., Lee G., and Srisuparp P. Inhaled nitric oxide in premature infants with the respiratory distress syndrome. N Engl J Med 349 (2003) 2099-2107
44. Van Meurs K.P., Wright L.L., Ehrenkranz R.A., Lemons J.A., Ball M.B., Poole W.K., et al. Inhaled nitric oxide for premature infants with severe respiratory failure. N Engl J Med 353 (2005) 13-22
45. Ballard R.A., Truog W.E., Cnaan A., Martin R.J., Ballard P.R., Merrill J.D., et al. Inhaled nitric oxide in preterm infants undergoing mechanical ventilation. N Engl J Med 205 (2006) 343-353
46. Kinsella J.P., Cutter G.R., Walsh W.F., Gerstmann D.R., Bose C.L., Hart C., et al. Early inhaled nitric oxide therapy in premature newborns with respiratory failure. N Engl J Med 205 (2006) 354-364
47. Mestan K.K., Marks J.D., Hecox K., Huo D., and Schreiber M.D. Neurodevelopmental outcomes of premature infants treated with inhaled nitric oxide. N Engl J Med 353 (2005) 23-32
48. Martin R.J., and Walsh M.C. Inhaled nitric oxide for preterm infants-Who benefits?. N Engl J Med 353 (2005) 82-84
49. Viscardi R.M., Muhumuza C.K., Rodriquez A., Fairchild K.D., Sun C.C., Gross G.W., et al. Inflammatory markers in intrauterine and fetal blood and cerebrospinal fluid compartments are associated with adverse pulmonary and neurologic outcomes in preterm infants. Pediatr Res 55 (2004) 1009-1017
50. Haynes R.L., Baud O., Li J., Kinney H.C., Volpe J.J., and Folkerth D.R. Oxidative and nitrative injury in periventricular leukomalacia. Brain Pathol 15 (2005) 225-233
51. Aaltonen M., Soukka H., Halkola L., Jalonen J., Kalimo H., Holopainen I.E., et al. Inhaled nitric oxide treatment inhibits neuronal injury after meconium aspiration in piglets. Early Human Dev 83 (2007) 77-85
52. Palowski J.R., Hess D.T., and Stamler J.S. Export by red blood cells of nitric oxide bioactivity. Nature 409 (2001) 622-626
53. Sugiura M., McCulloch P.R., Wren S., Dawson R.H., and Froese A.B. Ventilator pattern influences neutrophil influx and activation in atelectasis-prone rabbit lung. J Appl Physiol 77 (1994) 1355-1365