Temporal Response of the Fetal Pulmonary Circulation to Pharmacologic Vasodilators

Proceedings of the Society for Experimental Biology and Medicine

Volumn 187, Issue 1, 1988, Pages 89-98

  Accurso, Frank J ^a   Wilkening, Randall B ^a  

^a UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINE; BRADYKININ; HISTAMINE;

ANIMAL EXPERIMENT; LEFT PULMONARY ARTERY; LUNG BLOOD FLOW; NONHUMAN; PRELIMINARY COMMUNICATION; SHEEP; VASODILATATION;

ACETYLCHOLINE; ANIMAL; BLOOD FLOW VELOCITY; BLOOD PRESSURE; BRADYKININ; GESTATIONAL AGE; HISTAMINE; KINETICS; LUNG; PULMONARY ARTERY; PULMONARY CIRCULATION; SHEEP; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; VASODILATION; VASODILATOR AGENTS;

EID: 0023836383     PISSN: 00379727     EISSN: 15353699     Source Type: Journal    
DOI: 10.3181/00379727-187-42642     Document Type: Article

References (33)

1. Dawes G.S., J.C. Mott, J.C. Widdicombe, Wyatt D.G., Changes in the lungs of the newborn lamb. J Physiol 121:141-162, 1953.
2. Cassin S., G.S. Dawes, J.C. Mott, B.B. Ross, Strang L.B., The vascular resistance of the foetal and newly ventilated lung of the lamb. J Physiol 171:61-79, 1964.
3. Leffler C.W., R.L. Tyler, S. Cassin. Effect of indomethacin on pulmonary vascular response to ventilation of fetal goats. Amer J Physiol 234:H346-H351, 1978.
4. Heymann M.A., J.I.E. Hoffman. Pulmonary hypertension in the newborn. In: Weir EK, Reeves JT, Eds. Pulmonary Hypertension. New York, Futura, pp 45-71, 1984.
5. Accurso F.J., B. Alpert, R.B. Wilkening, R.G. Petersen, Meschia G., Time-dependent response of fetal pulmonary blood flow to an increase in fetal oxygen tension. Resp Physiol 63:43-52, 1986.
6. Barrett C.T., M.A. Heymann, Rudolph A.M., Alpha and beta receptor activity in fetal sheep. Amer J Obstet Gynecol 8:1114-1121, 1972.
7. Lewis A.B., M.A. Heymann, Rudolph A.M., Gestational changes in pulmonary vascular responses in fetal lambs in utero. Circulation Res 39:536-541, 1976.
8. Anderson D.F., J.M. Bissonnette, J.J. Faber, K.L. Thornburg. Central shunt flows and pressures in the mature fetal lamb. Amer J Physiol 241:H60-H66, 1981.
9. Abman S.H., R.B. Wilkening, R.M. Ward, Accurso F.J., Adaptation of fetal pulmonary blood flow to local infusion of tolazoline. Pediatr Res 20:1131-1135, 1986.
10. Lock J.E., F. Hamilton, H. Luide, F. Coceani, Olley P.M., Direct pulmonary vascular responses in the conscious newborn lamb. J Appl Physiol 48:188-196, 1980.
11. Truog R., F.J. Accurso, R.B. Wilkening, G. Meschia. Fetal pulmonary vasodilation with histamine: Mediation by H1 and H2 receptors. Pediatr Res 18:161 A, 1984.
12. SAS User’s Guide: Statistics—1982 Edition. Cary, NC, SAS Institute.
13. Snedecor G.W., W.G. Cochran. Statistical Methods. Ames, IA, Iowa State Univ Press, pp 301-310, 1967.
14. Rudolph A.M., Heymann M.A., Circulation changes during growth in the fetal lamb. Circ Res 26, 289-299, 1970.
15. Fishman A.P., Pulmonary circulation. In: Fishman AP, Ed. Handbook of Physiology. Sect 3: Respiratory System. Baltimore, Physiol Soc, pp 83-165, 1985.
16. Joiner P.D., P.J. Kadowitz, J.P. Hughes, Hyman A.L., NE and ACh responses of intrapulmonary vessels from dog, swine, sheep, and man. Amer J Physiol 228:1821-1827, 1975.
17. Fritts H.W., P. Harris, R.H. Clauss, J.E. Odell, Cournand A., The effect of acetylcholine on the human pulmonary circulation under normal and hypoxic conditions. J Clin Invest 37:99-108, 1958.
18. Malik A.B., Kidd S.L., Time course of pulmonary vascular response to hypoxia in dogs. Amer J Physiol 224:1-6, 1973.
19. Tucker A., Reeves J.T., Nonsustained pulmonary vasoconstriction during acute hypoxia in anesthetized dogs. Amer J Physiol 228:756-761, 1975.
20. Peake M.D., A.L. Harabin, N.J. Brennan, Sylvester J.T., Steady-state vascular responses to graded hypoxia in isolated lungs of five species. J Appl Physiol 5:1214-1219, 1981.
21. Bressack M.A., Bland R.D., Intravenous infusion of tolazoline reduces pulmonary vascular resistance and net fluid filtration in the lungs of awake hypoxic lambs. Amer Rev Respir Dis 123:217-221.
22. Dawes G.S., Mott J.C., The vascular tone of the foetal lung. J Physiol 164:465-477, 1962.
23. Campbell A.G.M., G.S. Dawes, A.P. Fishman, A.I. Hyman, Perks A.M., The release of a bradykinin-like pulmonary vsaodilator substance in foetal and new-born lambs. J Physiol 195:83-96, 1968.
24. Tod M.L., S. Cassin, D.B. McNamara, Kadowitz P.J., Effects of prostaglandin H2 on perinatal pulmonary circulation. Pediatr Res 20:565-569, 1986.
25. Clozel M., R.I. Clyman, S.J. Soifer, Heymann M.A., Thromboxane is not responsible for the high pulmonary vascular resistance in fetal lambs. Pediatr Res 19:1254-1257, 1985.
26. Sideris E.B., K. Yokochi, F. Coceani, P.M. Olley. Prostaglandins and fetal cardiac output distribution in the lamb. Amer J Physiol 248:H858-H858, 1985.
27. Tod M.L., Cassin S., Thromboxane synthase inhibition and perinatal pulmonary response to arachidonic acid. J Appl Physiol 58:710-716, 1985.
28. Rudolph A.M., Fetal and neonatal pulmonary circulation. Amer Rev Respir Dis 115:11-18, 1977.
29. Soifer S.J., R.D. Loitz, C. Roman, M.A. Heymann. Leukotriene end organ antagonists increase pulmonary blood flow in fetal lambs. Amer J Physiol 249:H570-H576, 1985.
30. Abman S.H., R.B. Wilkening, F.J. Accurso. Temporal response of the fetal pulmonary circulation to local infusion of arachidonic acid and prostaglandins. Amer Rev Respir Dis 131:A255, 1985.
31. Furchgott R.F., J.V. Zawadzki. The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine. Nature (London) 288: 373–376, 1980.
32. Minnear F.L., C.M. Kivlen, Malik A.B., Effect of bradykinin on lung vascular permeability in sheep. J Appl Physiol 55:1079-1084, 1983.
33. Fry D.L., Acute vascular endothelial changes associated with increased blood velocity gradients. Circ Res 22:165-197, 1968.