Evidence for aconitine-induced inhibition of delayed rectifier K+ current in Jurkat T-lymphocytes

Toxicology

Volumn 289, Issue 1, 2011, Pages 11-18

  Wu, Sheng Nan ^a   Chen, Bing Shuo ^a   Lo, Yi Ching ^b  

^a NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^b KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Aconitine; Inactivation kinetics; K+ current; Lymphocyte

Indexed keywords

1 ETHYL 2 BENZIMIDAZOLINONE; ACONITINE; AMILORIDE; DELAYED RECTIFIER POTASSIUM CHANNEL; DITERPENOID; MARGATOXIN; NICOTINE;

ARTICLE; DISSOCIATION CONSTANT; HUMAN; HUMAN CELL; HYPERPOLARIZATION; IC 50; IMMUNOCOMPETENT CELL; IN VIVO STUDY; ION CURRENT; KINETICS; LEUKEMIA CELL LINE; POTASSIUM CURRENT; PRIORITY JOURNAL;

ACONITINE; ANIMALS; BENZIMIDAZOLES; CALCIUM CHANNEL AGONISTS; CELL LINE; DELAYED RECTIFIER POTASSIUM CHANNELS; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; INHIBITORY CONCENTRATION 50; JURKAT CELLS; KINETICS; MACROPHAGES; MICE; PATCH-CLAMP TECHNIQUES; SCORPION VENOMS;

MURINAE;

EID: 80051820514     PISSN: 0300483X     EISSN: 18793185     Source Type: Journal    
DOI: 10.1016/j.tox.2011.07.003     Document Type: Article

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