Characterization of aconitine-induced block of delayed rectifier K+ current in differentiated NG108-15 neuronal cells

Neuropharmacology

Volumn 54, Issue 6, 2008, Pages 912-923

  Lin, Ming Wei ^a   Wang, Ya Jean ^a   Liu, Shiuh Inn ^b   Lin, An An ^a   Lo, Yi Ching ^c   Wu, Sheng Nan ^a  

^a NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^b KAOHSIUNG VETERANS GENERAL HOSPITAL   (Taiwan)

^c KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Aconitine; Action potential; Delayed rectifier K+ current; Na+ current; NG108 15 cells

Indexed keywords

ACONITINE; DELAYED RECTIFIER POTASSIUM CHANNEL; METHYLLYCACONITINE; ORPHENADRINE; SODIUM;

ACTION POTENTIAL; ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL MEMBRANE POTENTIAL; CONCENTRATION RESPONSE; CONTROLLED STUDY; DISSOCIATION CONSTANT; DRUG EFFECT; HUMAN; HUMAN CELL; IC 50; ION CURRENT; MOUSE; NERVE CELL; NEUROBLASTOMA CELL; NONHUMAN; PRIORITY JOURNAL; RAT; STEADY STATE;

ACONITINE; ACTION POTENTIALS; ALGORITHMS; CELL DIFFERENTIATION; CELL LINE; COMPUTER SIMULATION; DATA INTERPRETATION, STATISTICAL; DELAYED RECTIFIER POTASSIUM CHANNELS; ELECTROPHYSIOLOGY; HUMANS; KINETICS; NEURONS; PATCH-CLAMP TECHNIQUES; POTASSIUM CHANNEL BLOCKERS;

EID: 41949130248     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2008.01.009     Document Type: Article

References (37)

1. Ameri A. The effects of Aconitum alkaloids on the central nervous system. Prog. Neurobiol. 1998 56 (1998) 211-235
2. Ameri A., Shi O., Aschoff J., and Peters T. Electrophysiological effects of aconitine in rat hippocampal slices. Neuropharmacology 35 (1996) 13-22
3. Amran M.S., Hashimoto K., and Homma N. Effects of sodium-calcium exchange inhibitors, KB-R7943 and SEA0400, on aconitine-induced arrhythmias in guinea pigs in vivo, in vitro, and in computer simulation studies. J. Pharmacol. Exp. Ther. 310 (2004) 83-89
4. +]: a tale of two inactivation mechanisms. Neuron 15 (1995) 951-960
5. Brown D.A., and Higashida H. Voltage and calcium-activated potassium currents in mouse neuroblastoma X rat glioma hybrid cells. J. Physiol. 397 (1988) 149-165
6. Decher N., Kumar P., Gonzalez T., Pirard B., and Sanguinetti M.C. Binding site of a novel Kv1.5 blocker: a "foot in the door" against atrial fibrillation. Mol. Pharmacol. 70 (2006) 1204-1211
7. Ermentrout G.B. Simulating, Analyzing, and Animating Dynamical System: A Guide to XPPAUT for Researchers and Students. Society for Industrial and Applied Mathematics (2002), SIAM, Philadelphia
8. Fernandez F.R., Morales E., Rashid A.J., Dunn R.J., and Turner R.W. Inactivation of Kv3.3 potassium channels in heterologous expression systems. J. Biol. Chem. 278 (2003) 40890-40898
9. + channels, toxicity and antinociceptive properties. Eur. J. Pharmacol. 337 (1997) 165-174
10. Fu M., Wu M., Qiao Y., and Wang Z. Toxicological mechanisms of Aconitum alkaloids. Pharmazie 61 (2006) 735-741
11. Hardick D.J., Cooper G., Scott-Ward T., Blagbrough I.S., Potter B.V., and Wonnacott S. Conversion of the sodium channel activator aconitine into a potent α7-selective nicotinic ligand. FEBS Lett. 365 (1995) 79-82
12. + current in projecting neurons from the globus pallidus. J. Neurophysiol. 82 (1999) 1512-1528
13. v1.7 expression. Neurochem. Res. 32 (2007) 1469-1475
14. Klemic K.G., Kirsch G.E., and Jones S.W. U-type inactivation of Kv3.1 and Shaker potassium channels. Biophys. J. 81 (2001) 814-826
15. Lien C.C., and Jonas P. Kv3 potassium conductance is necessary and kinetically optimized for high-frequency action potential generation in hippocampal interneurons. J. Neurosci. 23 (2003) 2058-2068
16. Ling K.K., Siow N.L., Choi R.C., and Tsim K.W. ATP potentiates the formation of AChR aggregate in the co-culture of NG108-15 cells with C2C12 myotubes. FEBS Lett. 579 (2005) 2469-2474
17. Lo Y.K., Chiang H.T., and Wu S.N. Effect of arvanil (N-arachidonoyl-vanillyl-amine), a nonpungent anandamide-capsaicin hybrid, on ion currents in NG108-15 neuronal cells. Biochem. Pharmacol. 65 (2003) 581-591
18. Lowe L., Matteucci M.J., and Schneir A.B. Herbal aconite tea and refractory ventricular tachycardia. New. Engl. J. Med. 353 (2005) 1532
19. Marom S. Slow changes in the availability of voltage-gated ion channels: effects on the dynamics of excitable membranes. J. Membr. Biol. 161 (1998) 105-113
20. Marom S., and Abbott L.F. Modeling state-dependent inactivation of membrane currents. J. Membr. Biol. 67 (1994) 515-520
21. Marom S., Goldstein S.A., Kupper J., and Levitan I.B. Mechanism and modulation of inactivation of the Kv3 potassium channels. Receptors Channels 1 (1993) 81-88
22. McGehee D.S., and Role L.W. Physiological diversity of nicotinic acetylcholine receptors expressed by vertebrate neurons. Annu. Rev. Physiol. 57 (1995) 521-546
23. Meves H., Schwarz J.R., and Wulfsen I. Separation of M-like current and ERG current in NG108-15 cells. Br. J. Pharmacol. 127 (1999) 1213-1223
24. Pubill D., Vergaguer E., Canudas A.M., Sureda F.X., Escubedo E., Camarasa J., Pallàs M., and Camins A. Orphenadrine prevents 3-nitropropionic acid-induced neurotoxicity in vitro and in vivo. Br. J. Pharmacol. 132 (2001) 693-702
25. + channels. Circulation Res. 82 (1998) 739-750
26. + channels designed for high-frequency repetitive firing. Trends Neurosci. 24 (2001) 517-526
27. Tateno T., and Robinson H.P. Quantifying noise-induced stability of a cortical fast-spiking cell model with Kv3-channel-like current. Biosystems 89 (2007) 110-116
28. Tojima T., Kobayashi S., and Ito E. Dual role of cyclic AMP-dependent protein kinase in neuritogenesis and synaptogenesis during neuronal differentiation. J. Neurosci. Res. 74 (2003) 829-837
29. Tsai T.Y., Tsai Y.C., Wu S.N., and Liu Y.C. Tramadol-induced blockade of delayed rectifier potassium current in NG108-15 neuronal cells. Eur. J. Pain 10 7 (2006) 597-601
30. 2+ signaling in GnRH-secreting neurons. Biophys. J. 79 (2000) 1310-1323
31. Wang S.Y., and Wang G.K. Voltage-gated sodium channels as primary targets of diverse lipid-soluble neurotoxins. Cell. Signal 15 (2003) 151-159
32. Wright S.N. Irreversible block of human heart (hH1) sodium channels by the plant alkaloid lappaconitine. Mol. Pharmacol. 59 (2001) 183-192
33. 3 cells. Biochem. Pharmacol. 71 (2006) 615-623
34. + current in NG108-15 neuronal cells. Neuropharmacology 41 (2001) 834-843
35. Xu H., Arita H., Hayashida M., Zhang L., Sekiyama H., and Hanaoka K. Pain-relieving effects of processed Aconiti tuber in CCI-neuropathic rats. J. Ethnopharmacol. 103 (2006) 392-397
36. Yamanaka H., Doi A., Ishibashi H., and Akaike N. Aconitine facilitates spontaneous transmitter release at rat ventromedial hypothalamic neurons. Br. J. Pharmacol. 135 (2002) 816-822
37. Yokoyama S., Imoto K., Kawamura T., Higashida H., Iwabe N., Miyata T., and Numa S. Potassium channels from NG108-15 neuroblastoma-glioma hybrid cells. FEBS Lett. 259 (1989) 37-42