Distant and new mutations in CTX-M-1 β-lactamase affect cefotaxime hydrolysis

Antimicrobial Agents and Chemotherapy

Volumn 55, Issue 9, 2011, Pages 4361-4368

  Pérez Llarena, Francisco José ^a   Kerff, Frédéric ^e   Abián, Olga ^b,c,d   Mallo, Susana ^a   Fernández, María Carmen ^a   Galleni, Moreno ^e   Sancho, Javier ^b   Bou, Germán ^a  

^a HOSPITAL JUAN CANALEJO   (Spain)

^b UNIVERSITY OF ZARAGOZA   (Spain)

^c INSTITUTO DE SALUD CARLOS III   (Spain)

^d HOSPITAL UNIVERSITARIO MIGUEL SERVET   (Spain)

^e UNIVERSITY OF LIÈGE   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; AMPICILLIN; ARGININE; ASPARAGINE; ASPARTIC ACID; BACTERIAL PROTEIN; BETA LACTAMASE CTX M; CEFALOTIN; CEFOTAXIME; CEFUROXIME; HISTIDINE; ISOLEUCINE; LEUCINE; METHIONINE; NITROCEFIN; PROLINE; SERINE; THREONINE; VALINE;

AMINO ACID SUBSTITUTION; ARTICLE; BACTERIAL GENE; BACTERIAL MUTATION; BACTERIUM MUTANT; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME STRUCTURE; ESCHERICHIA COLI; GENE EXPRESSION; GENE LOCATION; GENETIC MODEL; HYDROLYSIS; HYDROPHOBICITY; MINIMUM INHIBITORY CONCENTRATION; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN PURIFICATION;

BETA-LACTAMASES; CEFOTAXIME; CIRCULAR DICHROISM; ESCHERICHIA COLI; HYDROLYSIS; KINETICS; MICROBIAL SENSITIVITY TESTS; MUTATION;

EID: 80051809443     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.00298-11     Document Type: Article

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