Humanized θ-defensins (retrocyclins) enhance macrophage performance and protect mice from experimental anthrax infections

Antimicrobial Agents and Chemotherapy

Volumn 55, Issue 9, 2011, Pages 4238-4250

  Welkos, S ^a   Cote, C K ^a   Hahn, U ^b   Shastak, O ^b   Jedermann, J ^b   Bozue, J ^a   Jung, G ^c   Ruchala, P ^c   Pratikhya, P ^c   Tang, T ^c   Lehrer, R I ^c   Beyer, W ^b  

^a UNITED STATES ARMY MEDICAL RESEARCH INSTITUTE OF INFECTIOUS DISEASES   (United States)

^b UNIVERSITY OF HOHENHEIM   (Germany)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DEFENSIN; DEFENSIN 1; POLYPEPTIDE ANTIBIOTIC AGENT; PROTEGRIN; PROTEGRIN 1; RETROCYCLIN 1; RETROCYCLIN 2; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTHRAX; ARTICLE; BACILLUS ANTHRACIS; BACTERIAL GROWTH; BACTERIAL SURVIVAL; BACTERICIDAL ACTIVITY; CELL LEVEL; COLONY FORMING UNIT; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFICACY; DRUG UPTAKE; ERYTHROCYTE; EXTRACELLULAR SPACE; FEMALE; HUMAN; IMMUNOSTIMULATION; LUNG ALVEOLUS MACROPHAGE; MOUSE; NONHUMAN; PHAGOCYTOSIS; PHAGOSOME; PRIORITY JOURNAL; PROTEIN BINDING; SERUM; SPORE GERMINATION;

ANIMALS; ANTHRAX; BACILLUS ANTHRACIS; CELL LINE; DEFENSINS; FEMALE; MACROPHAGES; MICE; MICE, INBRED BALB C; PHAGOCYTOSIS;

EID: 80051809310     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.00267-11     Document Type: Article

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